LOCUS BC034511 2571 bp mRNA linear HUM 19-JUN-2008
DEFINITION Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 4, mRNA (cDNA
clone MGC:9413 IMAGE:3882622), complete cds.
ACCESSION BC034511
VERSION BC034511.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2571)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2571)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 21 Row: p Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62422555.
FEATURES Location/Qualifiers
source 1..2571
/db_xref="H-InvDB:HIT000051176"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9413 IMAGE:3882622"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2571
/gene="PAK4"
/db_xref="GeneID:10298"
/db_xref="HGNC:HGNC:16059"
/db_xref="MIM:605451"
CDS 227..1732
/gene="PAK4"
/codon_start=1
/product="PAK4 protein"
/protein_id="AAH34511.1"
/db_xref="GeneID:10298"
/db_xref="HGNC:HGNC:16059"
/db_xref="MIM:605451"
/translation="MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE
ESARRPKPLVDPACITSIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRR
DSPPPPARARQENGMPEEPATTARGGPGKGEPHDVAPNGPSAGGLAIPQSSSSSSRPP
TRARGAPSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAAL
QLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNE
VVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAV
LQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWM
APELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHK
VSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR"
BASE COUNT 497 a 867 c 779 g 428 t
ORIGIN
1 gggattcaac atggcggcgg ggtgtccgcg gtggtggcgg tgcaagagag ctgaaggagg
61 cgcgagggcg cggagttcca ggccgagcag ttaggccgcg agcgactgcg gcgccgagcc
121 gatgagtaac ccgaagcccc tagaggagtg gtcacctgcc tgagggcact tctgtcccac
181 cagcatcaga ccaggtgtgt gcaggccgca ccgagtcccc ggcaccatgt ttgggaagag
241 gaagaagcgg gtggagatct ccgcgccgtc caacttcgag caccgcgtgc acacgggctt
301 cgaccagcac gagcagaagt tcacggggct gccccgccag tggcagagcc tgatcgagga
361 gtcggctcgc cggcccaagc ccctcgtcga ccccgcctgc atcacctcca tccagcccgg
421 ggcccccaag accatcgtgc ggggcagcaa aggtgccaaa gatggggccc tcacgctgct
481 gctggacgag tttgagaaca tgtcggtgac acgctccaac tccctgcgga gagacagccc
541 gccgccgccc gcccgtgccc gccaggaaaa tgggatgcca gaggagccgg ccaccacggc
601 cagagggggc ccagggaagg gggagcctca tgacgtggcc cctaacgggc catcagcggg
661 gggcctggcc atcccccagt cctcctcctc ctcctcccgg cctcccaccc gagcccgagg
721 tgcccccagc cctggagtgc tgggacccca cgcctcagag ccccagctgg cccctccagc
781 ctgcaccccc gccgcccctg ctgttcctgg gccccctggc ccccgctcac cacagcggga
841 gccacagcga gtatcccatg agcagttccg ggctgccctg cagctggtgg tggacccagg
901 cgacccccgc tcctacctgg acaacttcat caagattggc gagggctcca cgggcatcgt
961 gtgcatcgcc accgtgcgca gctcgggcaa gctggtggcc gtcaagaaga tggacctgcg
1021 caagcagcag aggcgcgagc tgctcttcaa cgaggtggta atcatgaggg actaccagca
1081 cgagaatgtg gtggagatgt acaacagcta cctggtgggg gacgagctct gggtggtcat
1141 ggagttcctg gaaggaggcg ccctcaccga catcgtcacc cacaccagga tgaacgagga
1201 gcagatcgcg gccgtgtgcc ttgcagtgct gcaggccctg tcggtgctcc acgcccaggg
1261 cgtcatccac cgggacatca agagcgactc gatcctgctg acccatgatg gcagggtgaa
1321 gctgtcagac tttgggttct gcgcccaggt gagcaaggaa gtgccccgaa ggaagtcgct
1381 ggtcggcacg ccctactgga tggccccaga gctcatctcc cgccttccct acgggccaga
1441 ggtagacatc tggtcgctgg ggataatggt gattgagatg gtggacggag agccccccta
1501 cttcaacgag ccacccctca aagccatgaa gatgattcgg gacaacctgc caccccgact
1561 gaagaacctg cacaaggtgt cgccatccct gaagggcttc ctggaccgcc tgctggtgcg
1621 agaccctgcc cagcgggcca cggcagccga gctgctgaag cacccattcc tggccaaggc
1681 agggccgcct gccagcatcg tgcccctcat gcgccagaac cgcaccagat gaggcccagc
1741 gcccttcccc tcaaccaaag agccccccgg gtcacccccg ccccactgag gccagtaggg
1801 ggccaggcct cccactcctc ccagcccggg agatgctccg cgtggcacca ccctccttgc
1861 tgggggtaga tgagacccta ctactgaact ccagttttga tctcgtgact tttagaaaaa
1921 cacagggact cgtgggagca agcgaggctc ccaggacccc caccctctgg gacaggccct
1981 cccccatgtt cttctgtctc caggaagggc agcggccctc ccatcactgg aagtctgcag
2041 tgggggtcgc tgggggtgga gagaacacta agaggtgaac atgtatgagt gtgtgcacgc
2101 gtgtgagtgt gcatgtgtgt gtgtgtgcaa aggtccagcc accccgtcct ccagcccgca
2161 aggggtgtct ggcgccttgc ctgacaccca gccccctctc cccctgagcc attgtggggg
2221 tcgatcatga atgtccgaag agtggccttt tcccgtagcc ctgcgccccc tttctgtggc
2281 tggatgggga gacaggtcag ggccccccac cctctccagc ccctgcagca aatgactact
2341 gcacctggac agcctcctct tttctagaag tctatttata ttgtcatttt ataacactct
2401 agcccctgcc cttattgggg gacagatggt ccctgtcctg cggggtggcc ctggcagaac
2461 cactgcctga agaaccaggt tcctgcccgg tcagcgcagc cccagcccgc ccacccctgc
2521 ctcgagttag ttttacaatt aaaacattgt cttgttaaaa aaaaaaaaaa a
//