LOCUS BC034490 4909 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens retinoblastoma-like 2 (p130), mRNA (cDNA clone
MGC:26535 IMAGE:4838444), complete cds.
ACCESSION BC034490
VERSION BC034490.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4909)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4909)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: o Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361291.
FEATURES Location/Qualifiers
source 1..4909
/db_xref="H-InvDB:HIT000051164"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26535 IMAGE:4838444"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4909
/gene="RBL2"
/gene_synonym="P130"
/gene_synonym="Rb2"
/db_xref="GeneID:5934"
/db_xref="HGNC:HGNC:9894"
/db_xref="MIM:180203"
CDS 109..3528
/gene="RBL2"
/gene_synonym="P130"
/gene_synonym="Rb2"
/codon_start=1
/product="retinoblastoma-like 2 (p130)"
/protein_id="AAH34490.1"
/db_xref="GeneID:5934"
/db_xref="HGNC:HGNC:9894"
/db_xref="MIM:180203"
/translation="MPSGGDQSPPPPPPPPAAAASDEEEEDDGEAEDAAPPAESPTPQ
IQQRFDELCSRLNMDEAARAEAWDSYRSMSESYTLEGNDLHWLACALYVACRKSVPTV
SKGTVEGNYVSLTRILKCSEQSLIEFFNKMKKWEDMANLPPHFRERTERLERNFTVSA
VIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTVSEIFHFCWVLFIYAKGNFPMI
SDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLSEDFHAKDSKPSSDPPCII
EKLCSLHDGLVLEAKGIKEHFWKPYIRKLYEKKLLKGKEENLTGFLEPGNFGESFKAI
NKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETAERVQMKNILQQHFD
KSKALRISTPLTGVRYIKENSPCVTPVSTATHSLSRLHTMLTGLRNAPSEKLEQILRT
CSRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCAKEIASKHFRFAEMLYYKVLESVIE
QEQKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPGNFPFITEIFDVPLYHFYK
VIEVFIRAEDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENRVPTCEEVMP
PQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPASTTRRRL
FVENDSPSDGGTPGRMPPQPLVNAVPVQNVSGETVSVTPVPGQTLVTMATATVTANNG
QTVTIPVQGIANENGGITFFPVQVNVGGQAQAVTGSIQPLSAQALAGSLSSQQVTGTT
LQVPGQVAIQQISPGGQQQKQGQSVTSSSNRPRKTSSLSLFFRKVYHLAAVRLRDLCA
KLDISDELRKKIWTCFEFSIIQCPELMMDRHLDQLLMCAIYVMAKVTKEDKSFQNIMR
CYRTQPQARSQVYRSVLIKGKRKRRNSGSSDSRSHQNSPTELNKDRTSRDSSPVMRSS
STLPVPQPSSAPPTPTRLTGANSDMEEEERGDLIQFYNNIYIKQIKTFAMKYSQANMD
APPLSPYPFVRTGSPRRIQLSQNHPVYISPHKNETMLSPREKIFYYFSNSPSKRLREI
NSMIHTGETPTKKRGILLEDGSESPAKRICPENHSALLRRLQDVANDRGSH"
BASE COUNT 1472 a 1021 c 1072 g 1344 t
ORIGIN
1 agcgggcagg cgcggtgcgg gcggcggacg ggcgggcgct tcgccgtttg aatggctgcg
61 ggcccgggcc ctcacctcac ctgaggtccg gccgcccagg ggtgcgctat gccgtcggga
121 ggtgaccagt cgccaccgcc cccgcctccc cctccggcgg cggcagcctc ggatgaggag
181 gaggaggacg acggcgaggc ggaagacgcc gcgccgcctg ccgagtcgcc cacccctcag
241 atccagcagc ggttcgacga gctgtgcagc cgcctcaaca tggacgaggc ggcgcgggcc
301 gaggcctggg acagctaccg cagcatgagc gaaagctaca cgctggaggg aaatgatctt
361 cattggttag catgtgcctt atatgtggct tgcagaaaat ctgttccaac tgtaagcaaa
421 gggacagtgg aaggaaacta tgtatcttta actagaatcc tgaaatgttc agagcagagc
481 ttaatcgaat tttttaataa gatgaagaag tgggaagaca tggcaaatct acccccacat
541 ttcagagaac gtactgagag attagaaaga aacttcactg tttctgctgt aatttttaag
601 aaatatgaac ccatttttca ggacatcttt aaataccctc aagaggagca acctcgtcag
661 cagcgaggaa ggaaacagcg gcgacagccc tgtactgtgt ctgaaatttt ccatttttgt
721 tgggtgcttt ttatatatgc aaaaggtaat ttccccatga ttagtgatga tttggtcaat
781 tcttatcacc tgctgctgtg tgctttggac ttagtttatg gaaatgcact tcagtgttct
841 aatcgtaaag aacttgtgaa ccctaatttt aaaggcttat ctgaagattt tcatgctaaa
901 gattctaaac cttcctctga ccccccttgt atcattgaga aactgtgttc cttacatgat
961 ggcctagttt tggaagcaaa ggggataaag gaacatttct ggaaacccta tattaggaaa
1021 ctttatgaaa aaaagctcct taagggaaaa gaagaaaatc tcactgggtt tctagaacct
1081 gggaactttg gagagagttt taaagccatc aataaggcct atgaggagta tgttttatct
1141 gttgggaatt tagatgagcg gatatttctt ggagaggatg ctgaggagga aattgggact
1201 ctctcaaggt gtctgaacgc tggttcagga acagagactg ctgaaagggt gcagatgaaa
1261 aacatcttac agcagcattt tgacaagtcc aaagcactta gaatctccac accactaact
1321 ggtgttaggt acattaagga gaatagccct tgtgtgactc cagtttctac agctacgcat
1381 agcttgagtc gtcttcacac catgctgaca ggcctcagga atgcaccaag tgagaaactg
1441 gaacagattc tcaggacatg ttccagagat ccaacccagg ctattgctaa cagactgaaa
1501 gaaatgtttg aaatatattc tcagcatttc cagccagacg aggatttcag taattgtgct
1561 aaagaaattg ccagcaaaca ttttcgtttt gcggagatgc tttactataa agtattagaa
1621 tctgttattg agcaggaaca aaaaagacta ggagacatgg atttatctgg tattctggaa
1681 caagatgcgt tccacagatc tctcttggcc tgctgccttg aggtcgtcac tttttcttat
1741 aagcctcctg ggaattttcc atttattact gaaatatttg atgtgcctct ttatcatttt
1801 tataaggtga tagaagtatt cattagagca gaagatggcc tttgtagaga ggtggtaaaa
1861 caccttaatc agattgaaga acagatctta gatcatttgg catggaaacc agagtctcca
1921 ctctgggaaa aaattagaga caatgaaaac agagttccta catgtgaaga ggtcatgcca
1981 cctcagaacc tggaaagggc agatgaaatt tgcattgctg gctccccttt gactcccaga
2041 agggtgactg aagttcgtgc tgatactgga ggacttggaa ggagcataac atctccaacc
2101 acattatacg ataggtacag ctccccacca gccagcacta ccagaaggcg gctatttgtt
2161 gagaatgata gcccctctga tggagggacg cctgggcgca tgcccccaca gcccctagtc
2221 aatgctgtcc ctgtgcagaa tgtatctggg gagactgttt ctgtcacacc agttcctgga
2281 cagactttgg tcaccatggc aaccgccact gtcacagcca acaatgggca aacggtaacc
2341 attcctgtgc aaggtattgc caatgaaaat ggagggataa cattcttccc tgtccaagtc
2401 aatgttgggg ggcaggcaca agctgtgaca ggctccatcc agcccctcag tgctcaggcc
2461 ctggctggaa gtctgagctc tcaacaggtg acaggaacaa ctttgcaagt ccctggtcaa
2521 gtggccattc aacagatttc cccaggtggc caacagcaga agcaaggcca gtctgtaacc
2581 agcagtagta atagacccag gaagaccagc tctttatcgc ttttctttag aaaggtatac
2641 catttagcag ctgtccgcct tcgggatctc tgtgccaaac tagatatttc agatgaattg
2701 aggaaaaaaa tctggacctg ctttgaattc tccataattc agtgtcctga acttatgatg
2761 gacagacatc tggaccagtt attaatgtgt gccatttatg tgatggcaaa ggtcacaaaa
2821 gaagataagt ccttccagaa cattatgcgt tgttatagga ctcagccgca ggcccggagc
2881 caggtgtata gaagtgtttt gataaaagga aaaagaaaaa gaagaaattc tggcagcagt
2941 gatagcagaa gccatcagaa ttctccaaca gaactaaaca aagatagaac cagtagagac
3001 tccagtccag ttatgaggtc aagcagcacc ttgccagttc cacagcccag cagtgctcct
3061 cccacaccta ctcgcctcac aggtgccaac agtgacatgg aagaagagga gaggggagac
3121 ctcattcagt tctacaacaa catctacatc aaacagatta agacatttgc catgaagtac
3181 tcacaggcaa atatggatgc tcctccactc tctccctatc catttgtaag aacaggctcc
3241 cctcgccgaa tacagttgtc tcaaaatcat cctgtctaca tttccccaca taaaaatgaa
3301 acaatgcttt ctcctcgaga aaagattttc tattacttca gcaacagtcc ttcaaagaga
3361 ctgagagaaa ttaatagtat gatacacaca ggagaaactc ctactaaaaa gagaggaatt
3421 cttttggaag atggaagtga atcacctgca aaaagaattt gcccagaaaa tcattctgcc
3481 ttattacgcc gtctccaaga tgtagctaat gaccgtggtt cccactgagg ttagtctctt
3541 gtattaaact cttcacaaaa tctgtttagc agcagccttt aatgcatcta gattatggag
3601 cttttttcct taatccagct gatgagttac agcctgttag taacatgagg ggacattttg
3661 gtgagaaatg ggacttaact ccttccagtg tccttagaac attttaattc atcccaactg
3721 tctttttttc cctaccattc agtgattact gtcaaggctg cttagaatcc aaacttggat
3781 ttttgactct ggcaaagctt ttagaaatac tgcaagaaaa tgatgtgtac ccaaacgtga
3841 gcataggagg cttctgttga cgtactccaa cagaagaact gttttcaagt tcaatcctac
3901 ctgttttgtg gtcagctgta gtcctcataa aaagcaaaac aaaaattagg tattttgtcc
3961 taaaacacct ggtaggagtg tgtgattttt tgcattcctg acaaaggaga gcacacccag
4021 gtttggaggt cctaggtcat tagccctcgt ctcccgttcc ctttgtgcac atcttccctc
4081 tccccattcg gtgtggtgca gtgtgaaaag tccttgattg ttcgggtgtg caatgtctga
4141 gtgaacctgt ataagtggag gcactttagg gctgtaaaat gcatgatttt gtaacccaga
4201 ttttgctgta tatttgtgat agcactttct acaatgtgaa ctttattaaa tacaaaactt
4261 ccaggctaaa catccaatat tttctttaat gcttttatat ttttttaaaa tgttaaaacc
4321 cctatagcca ccttttggga atgttttaaa ttctccagtt ttttgttata tagggatcaa
4381 ccagctaaga aaagatttta atcaagttga attgagggga ttaatatgaa aacttatgac
4441 ctcttccttt aggagggagt tatctaaaag aaatgtctat taaggtgata tatttaaaaa
4501 tatttttggg tgttcctggc agtttaaaaa aattggttgg agaatttagg tttttattag
4561 taccatagta ccatttatac aaattagaaa atgttattta acagctgaat tatctataca
4621 tatctttatt aatcactatt gttccagcag ttttcaagtc aaattaataa tcttattagg
4681 gagaaaattc aattgtaaat tgaatcagta taaacaaagt tactaggtaa cttcatattg
4741 ctgagagaaa tatggaactt acattgttca attagaatag tgttctgcaa aaatatttat
4801 aaaacttctc aagatactgc tactgtaatt ttatatgaag ataagtgtat ttttcaataa
4861 agcatttata aattaaaaaa aaaaaaaaaa aaacaaaaaa aaaaaaaaa
//