LOCUS BC034395 2161 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dihydropyrimidinase, mRNA (cDNA clone MGC:34608
IMAGE:5187250), complete cds.
ACCESSION BC034395
VERSION BC034395.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2161)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2161)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 50 Row: h Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503374.
FEATURES Location/Qualifiers
source 1..2161
/db_xref="H-InvDB:HIT000042121"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34608 IMAGE:5187250"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2161
/gene="DPYS"
/gene_synonym="DHP"
/gene_synonym="DHPase"
/db_xref="GeneID:1807"
/db_xref="HGNC:HGNC:3013"
/db_xref="MIM:222748"
CDS 94..1653
/gene="DPYS"
/gene_synonym="DHP"
/gene_synonym="DHPase"
/codon_start=1
/product="dihydropyrimidinase"
/protein_id="AAH34395.1"
/db_xref="GeneID:1807"
/db_xref="HGNC:HGNC:3013"
/db_xref="MIM:222748"
/translation="MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGG
APAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFA
IPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKM
FMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHE
LCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAAS
LGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQ
KALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRK
GRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA
GVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKED
ATAGTRKQAHP"
BASE COUNT 628 a 499 c 533 g 501 t
ORIGIN
1 accttgcagg agggcacccc aagcccgccc ggcccgccca acccagcccc tgcgcgcagc
61 ccgggccgag taggaccccg cgcgcccctc gccatggcgg cgccctcgcg gctcctgatc
121 cgcgggggtc gcgtggtcaa cgatgacttc tcggaggtgg ccgacgtgct ggtggaggac
181 ggcgtggtgc gggcactcgg gcacgacctg ctgcctcccg ggggcgctcc tgcggggctg
241 cgggtcctcg acgccgccgg caagctcgtc ctgcccggag gcatcgacac acacacgcac
301 atgcagttcc ccttcatggg ctcgcggtcc atcgacgact tccaccaggg caccaaggct
361 gctctctcag gaggcaccac catgattatt gatttcgcca ttcctcagaa aggtggctcc
421 ctcattgagg ccttcgagac ctggcgaagc tgggctgatc ccaaagtttg ctgcgactac
481 agccttcatg tggcagtgac gtggtggagt gaccaggtta aagaagaaat gaaaatcctt
541 gtgcaagata aaggtgttaa ctctttcaag atgtttatgg cctataaaga tctgtacatg
601 gtgacagacc tggagctgta cgaagccttc tctcggtgca aggaaattgg agcaattgcc
661 caggtccatg cggaaaatgg agacttaatt gcagagggag caaagaagat gttggctctg
721 gggataacag gccctgaggg ccacgagctg tgccgcccag aggcagtgga ggcagaggcc
781 acgctgagag ccatcaccat agccagcgct gtgaactgtc ctctctacat tgtgcatgtg
841 atgagcaagt ctgcagctaa ggtgatagcg gatgcaagga gagatgggaa ggtggtctat
901 ggtgaaccca tagcagccag tcttggcaca gatggcactc actactggaa taaagaatgg
961 caccatgcag cccaccatgt catgggtcca cctttgcgac cagacccctc aacacccgac
1021 ttcctcatga atctgttggc taatgatgat ctaaccacaa cagggactga taactgcact
1081 ttcaacacct gccagaaagc tcttgggaag gatgatttta ccaagatccc caatggggtg
1141 aatggtgttg aagatcggat gtccgtaata tgggaaaaag gcgtgcatag tggtaaaatg
1201 gatgaaaaca gatttgtggc agttaccagc acaaatgcag ccaaaatttt taatctctat
1261 ccaagaaaag gaagaatagc tgtaggatca gatgctgaca ttgttatttg ggacccaaaa
1321 ggcacaagga ctatctcagc aaaaactcat catcaggctg ttaacttcaa cattttcgag
1381 ggcatggttt gccacggggt gccccttgtg actatttcaa gaggcaaagt ggtatatgaa
1441 gccggagtgt tcagtgtcac ggcaggagat gggaagttta ttcctcgaaa accatttgct
1501 gaatatattt acaaacgaat aaagcagcga gaccggactt gcacacctac ccctgtggag
1561 cgtgcaccct ataagggaga agtcgccaca ctgaaatcca gagtgacaaa agaagatgcc
1621 acagcaggga ccaggaaaca ggcccacccc tgaagtgtgt gccatcggta aaaaaatcag
1681 aggaaaggag gctgccattc ccttcacagc caaacattgt caacccatgg agaagcaggc
1741 cttattcaac tccctaggat cctttagaaa aaattcacca ctataggctt ctttgatttt
1801 ctttcagaag caattgctgt ctttctcact gtgtttttgt tgctgcataa gattgaaggt
1861 ataaatttat attattgtga tggaaaggct gtgtggaaat tcattgatga tactttaaaa
1921 tgtcatcttt gcttgtacta gatttcttac ttagaatttt taaaaatcat tttcttgttt
1981 aaatagtttc tttttttaaa aaaatggtta cattagtttt aaaatagctc tgtgatttta
2041 ctttttattg taattaataa acattgagat cttcatttta taccttaaaa aaaaaaaaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 a
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