LOCUS BC033752 2020 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens cytochrome P450, family 20, subfamily A, polypeptide
1, mRNA (cDNA clone MGC:45025 IMAGE:5211537), complete cds.
ACCESSION BC033752
VERSION BC033752.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2020)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2020)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: o Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29171729
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..2020
/db_xref="H-InvDB:HIT000041937"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45025 IMAGE:5211537"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2020
/gene="CYP20A1"
/gene_synonym="CYP-M"
/db_xref="GeneID:57404"
/db_xref="HGNC:HGNC:20576"
CDS 55..1443
/gene="CYP20A1"
/gene_synonym="CYP-M"
/codon_start=1
/product="CYP20A1 protein"
/protein_id="AAH33752.1"
/db_xref="GeneID:57404"
/db_xref="HGNC:HGNC:20576"
/translation="MLDFAIFAVTFLLALVGAVLYLYPASRQAAGIPGITPTEEKDGN
LPDIVNSGSLHEFLVNLHERYGPVVSFWFGRRLVVSLGTVDVLKQHINPNKTLDPFET
MLKSLLRYQSGGGSVSENHMRKKLYENGVTDSLKSNFALLLKLSEELLDKWLSYPETQ
HVPLSQHMLGFAMKSVTQMVMGSTFEDDQEVIRFQKNHGTVWSEIGKGFLDGSLDKNM
TRKKQYEDALMQLESVLRNIIKERKGRNFSQHIFIDSLVQGNLNDQQILEDSMIFSLA
SCIITAKLCTWAICFLTTSEEVQKKLYEEINQVFGNGPVTPEKIEQLRYCQHVLCETV
RTAKLTPVSAQFQDIEGKIDRFIIPRETLVLYALGVVLQDPNTWPSPHKFDPDRFDDE
LVMKTFSSLGFSGTQECPELRFAYMVTTVLLSVLVKRLHLLSVEGQVIETKYELVTSS
REEAWITVSKRY"
BASE COUNT 613 a 360 c 420 g 627 t
ORIGIN
1 ggcgctgctg ctggagcggc cgatccgaga cgtggctccc tgggcggcag aaccatgttg
61 gacttcgcga tcttcgccgt taccttcttg ctggcgttgg tgggagccgt gctctacctc
121 tatccggctt ccagacaagc tgcaggaatt ccagggatta ctccaactga agaaaaagat
181 ggtaatcttc cagatattgt gaatagtgga agtttgcatg agttcctggt taatttgcat
241 gagagatatg ggcctgtggt ctccttctgg tttggcaggc gcctcgtggt tagtttgggc
301 actgttgatg tactgaagca gcatatcaat cccaataaga cattggaccc ttttgaaacc
361 atgctgaagt cattattaag gtatcaatct ggtggtggca gtgtgagtga aaaccacatg
421 aggaaaaaat tgtatgaaaa tggtgtgact gattctctga agagtaactt tgccctcctc
481 ctaaagcttt cagaagaatt attagataaa tggctctcct acccagagac ccagcacgtg
541 cccctcagcc agcatatgct tggttttgct atgaagtctg ttacacagat ggtaatgggt
601 agtacatttg aagatgatca ggaagtcatt cgcttccaga agaatcatgg cacagtttgg
661 tctgagattg gaaaaggctt tctagatggg tcacttgata aaaacatgac tcggaaaaaa
721 caatatgaag atgccctcat gcaactggag tctgttttaa ggaacatcat aaaagaacga
781 aaaggaagga acttcagtca acatattttc attgactcct tagtacaagg gaaccttaat
841 gaccaacaga tcctagaaga cagtatgata ttttctctgg ccagttgcat aataactgca
901 aaattgtgta cctgggcaat ctgtttttta accacctctg aagaagttca aaaaaaatta
961 tatgaagaga taaaccaagt ttttggaaat ggtcctgtta ctccagagaa aattgagcag
1021 ctcagatatt gtcagcatgt gctttgtgaa actgttcgaa ctgccaaact gactccagtt
1081 tctgcccagt ttcaagatat tgaaggaaaa attgaccgat ttattattcc tagagagacc
1141 ctcgtccttt atgcccttgg tgtggtactt caggatccta atacttggcc atctccacac
1201 aagtttgatc cagatcggtt tgatgatgaa ttagtaatga aaactttttc ctcacttgga
1261 ttctcaggca cacaggagtg tccagagttg aggtttgcat atatggtgac cacagtactt
1321 cttagtgtat tggtgaagag actgcaccta ctttctgtgg agggacaggt tattgaaaca
1381 aagtatgaac tggtaacatc atcaagggaa gaagcttgga tcactgtctc aaagagatat
1441 taaaatttta tacatttaaa atcattgtta aattgattga ggaaaacaac catttaaaaa
1501 aaatctatgt tgaatccttt tataaaccag tatcactttg taatataaac acctatttgt
1561 acttaatttt gtaaatttgg atttttatat atcatatttt cttaattcat tgtacacatt
1621 tgacttactg cacagtatat tgatcatttt aatgggaaac tttagctttc tactttttat
1681 ttttgttttt ttcactttct atgccattat ttttgtattc tttttcttag tgtgagctct
1741 aaaatcaatg ttcttgaaaa agaaattatt ttgcagaagt tggggaatca tgtttgttga
1801 atatgtataa aatagaaaca taggctcggc ctcccagggt gctcggattg cagacgtgag
1861 ccactgcgcc cggcccgttg gcttgctttc tagatactgg gaatagatct tgttatagta
1921 tgtgataaat agatcttgtt atagtatgtg ataaaatgcc atgatcaaat aaattactta
1981 tatcctgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//