LOCUS BC033735 4260 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens protocadherin alpha 5, mRNA (cDNA clone MGC:44897
IMAGE:5175471), complete cds.
ACCESSION BC033735
VERSION BC033735.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4260)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4260)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: k Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14165414.
FEATURES Location/Qualifiers
source 1..4260
/db_xref="H-InvDB:HIT000041928"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44897 IMAGE:5175471"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4260
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/db_xref="GeneID:56143"
/db_xref="MIM:606311"
CDS 140..2812
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/codon_start=1
/product="PCDHA5 protein"
/protein_id="AAH33735.1"
/db_xref="GeneID:56143"
/db_xref="MIM:606311"
/translation="MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFV
GRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECS
IHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLD
IGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGK
PELTGTVQLLINVLDANDSAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEI
VYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCK
VVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHV
PFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDN
APAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVS
VHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLV
PRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVG
LYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVESGQAPKASSRAS
AGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEAVCTRGKPTLLC
SSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASL
RAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK
YGPGNPKQSGPEPKKQTQVSFLLRRKGEASQPRQ"
misc_feature 326..529
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
misc_feature 605..856
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
misc_feature 926..1180
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
misc_feature 1250..1495
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
misc_feature 1565..1825
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
misc_feature 1916..2149
/gene="PCDHA5"
/gene_synonym="CNR6"
/gene_synonym="CNRN6"
/gene_synonym="CNRS6"
/gene_synonym="CRNR6"
/gene_synonym="PCDH-ALPHA5"
/note="CA; Region: Cadherin repeats. Cadherins are
glycoproteins involved in Ca2+-mediated cell-cell
adhesion. Cadherin domains occur as repeats in the
extracellular regions which are thought to mediate
cell-cell contact when bound to calcium"
/db_xref="CDD:smart00112"
BASE COUNT 1165 a 1004 c 1082 g 1009 t
ORIGIN
1 aagaaccttc catttttggc tgtgccaaga agctcagaaa ggcgataata taaaaaatat
61 atagttaatt gggaattgaa tttacaaaat acattgtgtg gtgatgcaat agaaagctca
121 taattggaac gagattgaga tggtatattc ccggagagga agtctgggat cccggctcct
181 gctgctctgg cttctccttg cctactggaa ggcagggagc ggccagctcc actactcgat
241 cccggaggaa gccaaacacg gaaccttcgt tggccgcatc gcgcaggacc tagggctgga
301 gctggcggag ctggtgccgc gcctgttccg ggtggcgtcc aagggccgcg gggaccttct
361 ggaggtaaat ctgcagaatg gcattttgtt tgtgaattct cggatcgacc gggaggagct
421 gtgccggcgg agggcggagt gcagcatcca cctggaggtg atcgtggaca ggccgctgca
481 ggttttccat gtggaggtgg cagtgaagga catcaatgac aatccgccca ggttctccag
541 acaagaacaa agattattca ttttagagtc aagaatgcca gattcgcggt ttccgctaga
601 gggcgcgtcg gatttggata ttggagcaaa tgcacaattg agatacaggt taaatccaaa
661 cgaatatttt gacttagatg ttaaaacaaa tgaagaagaa acgaactttt tagagctggt
721 tttgaggaaa tccttagata gagaagaaac acaagaacac cgtttattag tgattgcaac
781 tgatggagga aaacccgaac taacaggtac agttcagttg ttgatcaatg tattggatgc
841 taatgatagc gccccagaat ttgataaatc catttataat gtcagattgt tggaaaatgc
901 accaagtggg acattagtta ttaaactgaa cgcctcagat gcagatgagg gcatcaataa
961 ggaaatagtg tatttcttta gtaatcttgt tcttgacgat gtaaagtcca aatttataat
1021 taattctaat actggtgaaa taaaagttaa cggggaactg gattatgaag actataactc
1081 atatgaaatt aatattgatg ccatggataa aagtacattc ccattatcag gacactgtaa
1141 agtagtagtg aaactcctgg atgtgaatga taatacccca gagatggcca taaccaccct
1201 tttcctgcct gtcaaagagg acgctccact cagcacggtc attgctctga tcagcgtgtc
1261 tgaccgtgac tcaggtgcca acgggcaggt gacctgctcc ctaatgcccc acgttccctt
1321 caagctggtg tccaccttca agaattacta ctcgttggtg ctggacagcg ccctggaccg
1381 cgagagcgtg tcggtctatg agctggtggt gaccgcgcgg gacgggggct cgccttcgct
1441 gtgggccacc gccagcgtgt ctgtggaagt ggccgacgtg aacgacaacg ctccggcgtt
1501 cgcgcagccc cagtataccg tgttcgtgaa ggagaacaac ccgccaggct gccacatctt
1561 cacggtgtct gcacgggacg cggacgcgca ggagaacgcc ctggtgtcct actcgctggt
1621 ggagcggcgg gtgggcgagc gcccgctgtc gagttacgtt tcggtgcacg cggagagcgg
1681 caaggtgtac gcgctgcagc cgctggacca cgaggaagtg gagctgctgc agttccaggt
1741 gagcgcgcgc gacgcgggcg tgccgcctct gggcagcaac gtgacgctgc aggtgttcgt
1801 gctggacgag aacgacaacg cgccggcgct gctggtgcct cgagtgggtg gcaccggcgg
1861 cgcagtgagc gagctggtgc cgaggtcagt gggtgcgggc cacgtggtgg cgaaggtgcg
1921 cgcagtggac cctgattcgg gctacaacgc ttggctttcg tatgagctgc agccagcgcc
1981 tggcagtgcg cgcatcccgt tccgcgtggg gctgtacaca ggcgagatca gcacaacacg
2041 ctctctggat gagaccgaag caccgcgcca ccgccttctg gtgctggtga aggaccatgg
2101 agagcccccg ctgacagcca cagccacagt gctggtgtcg ctggtggaaa gtggccaggc
2161 gccgaaggcc tcatcgcggg cgtcggcggg cgctgtgggt cccgaggctg ccctggtgga
2221 tgtcaacgtg tacctgatca tcgccatctg tgcggtgtcc agcctgctgg tgctcacgct
2281 gctgctgtac accgcgctgc ggtgctcggc gcagcccacc gaggccgtgt gcacacgggg
2341 caagcccact ctgttgtgct ccagcgcggt ggggagctgg tcgtactcgc agcagaggag
2401 acagagggtg tgctctgggg aagctccacc caaaacagac ctcatggcct tcagtccaag
2461 ccttcctcag ggtcccacct ctacagacaa cccacgacag cccaaccctg actggcgtta
2521 ctctgcctcc ctgagagcag gcatgcacag ctctgtgcac ctagaggagg ctggcattct
2581 acgggctggt ccaggagggc ctgatcagca gtggccaaca gtatccagtg caacaccaga
2641 accagaggca ggagaagtgt cccctccagt cggtgcgggt gtcaacagca acagctggac
2701 ctttaaatac ggaccaggca accccaaaca atccggtccc gaacctaaaa agcagaccca
2761 agtttccttt ctcctccgcc gcaaaggaga ggcttcccag ccccgccagt gagaggttgg
2821 actctctgcc ctgtgctccg gggatcctgt cttgatgaca cttgcagggc aggctgaaaa
2881 gttttgagat tgagcagctt gggagtttgt ggccactggg tatgtgtggc taccgcgggt
2941 atgcgagtgc cagatattgg ctgagacgag ccagcttaga ctaattggta caaggaaggc
3001 aagaaaacaa agacaaataa acagcggaag ttatcagtat ggaggggaag tgtaaactta
3061 aagggaccag actttctaaa tcttacaact caagaggtgg cagccaccct ctaggagaca
3121 aaactacccc cactgacaag gctttaggag accctaaagt ctgttggctg tgacgtcatt
3181 atacctaaaa tctgcatcat acctgcaagc caacagttca gtgttttaac agagaaccac
3241 cctgggaaac agaagcagat ctgatgtgtt tcctatacat gtcctgtgct cactttatta
3301 aaaattcttt tgcacacaat gtttatgaaa aggccagatc cttttccaat acttatgcaa
3361 aagcaaaaga aaaccccgac acctcacctt tcgctgtttg ttgtttcata gatttattta
3421 aaaaaagaga aagtctatag ctataaatct ttaaagagaa atatgaatac aattccccta
3481 aactctcctc aaaagagaat tcagtctaca gccatttaaa tgatcattgc tgctacagaa
3541 gtgctttaag agaattgcct gaaacatctg tattatatcg gccacctgcc aatcacagct
3601 ttactctttc aggtcactct ggggctgcct cttgcatgta ttactaaata aaatgatctc
3661 tctttctctc tctctctctc ttttctaaga aacaattatg tgcactttga tacacaacct
3721 tctctaacca actatatatc aagacccaaa aattgaagaa aaatattgtt ttctcataca
3781 gtgagcagat ttttcaatct actaattctg tgacttgtct tggtgtgcta gcctacacct
3841 tctctttggt ttagttttcc ttttctataa cactctgaat tgctaatctt actaacacct
3901 atgatgttac ctgaaatcaa tctcccatat gtatgctgta tgctatgcta agactcctga
3961 aatatactta ctctgtgctt gtgtatgtga atgttaatgc aactattacc tagagtgaac
4021 tttaagcttt attgttgaat gtaattccat tatatttcct tttgtacacc tgtgaaaaag
4081 tggagtagtg tttttttaac cattgttaat cagcttttgt gtatgaaaga cacagtaaaa
4141 tttctttctt aaatcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4201 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//