LOCUS BC033719 2413 bp mRNA linear HUM 26-JUL-2018
DEFINITION Homo sapiens sestrin 2, mRNA (cDNA clone MGC:44920 IMAGE:4931535),
complete cds.
ACCESSION BC033719
VERSION BC033719.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2413)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2413)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
REFERENCE 3 (bases 1 to 2413)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JUL-2018) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Jul 26, 2018 this sequence version replaced BC033719.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: g Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32454742.
FEATURES Location/Qualifiers
source 1..2413
/db_xref="H-InvDB:HIT000041917"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44920 IMAGE:4931535"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2413
/gene="SESN2"
/gene_synonym="DKFZp761M0212"
/gene_synonym="DKFZp761M02121"
/gene_synonym="HI95"
/gene_synonym="SES2"
/gene_synonym="SEST2"
/db_xref="GeneID:83667"
/db_xref="HGNC:HGNC:20746"
/db_xref="MIM:607767"
CDS 308..1750
/gene="SESN2"
/gene_synonym="DKFZp761M0212"
/gene_synonym="DKFZp761M02121"
/gene_synonym="HI95"
/gene_synonym="SES2"
/gene_synonym="SEST2"
/codon_start=1
/product="sestrin 2"
/protein_id="AAH33719.1"
/db_xref="GeneID:83667"
/db_xref="HGNC:HGNC:20746"
/db_xref="MIM:607767"
/translation="MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGP
SAFIPVEEVLREGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLH
TDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLS
EINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILP
EGDADGSPAPQAPTPPSEQSSPPSRDPLNNSGGFESARDVEALMERMQQLQESLLRDE
GTSQEEMESRFELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAP
PTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRA
IWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHS
EKVHVNLLLLEARMQAALLYALRAITRYMT"
BASE COUNT 456 a 777 c 702 g 478 t
ORIGIN
1 gctgaggagc gctgggtccg ggagcagccc tggcccctgc ggacttccga ggccgtgaaa
61 acccctgcgc tgcggccctt cccaggcccc cgaggccgtt cgccgttccc gaagcccgac
121 tgggggaaga gtccagcacc aaagcggccg ttctcggatt ccggagcgtt ctggagcccc
181 gagagacgcc ccggggttct agaagctccc cggcggcgcc cagtcccggc ttcattcggg
241 cgtccctccg aaacccactc gggtgcacgg gtcgtcggcg agccgcgacc gggtcctggc
301 gcgcaccatg atcgtggcgg actccgagtg ccgcgcagag ctcaaggact acctgcggtt
361 cgccccgggc ggcgtcggcg actcgggccc cggagaggag cagagggaga gccgggctcg
421 gcgaggccct cgagggccca gcgccttcat ccccgtggag gaggtccttc gggagggggc
481 tgagagcctc gagcagcacc tggggctgga ggcactgatg tcctctgggc gagtagacaa
541 cctggcagtg gtgatgggcc tgcaccctga ctactttacc agcttctggc gcctgcacta
601 cctgctgctg cacacggatg gtcccttggc cagctcctgg cgccactaca ttgccatcat
661 ggctgccgcc cgccatcagt gttcttacct ggtaggctcc cacatggccg agtttctgca
721 gactggtggt gaccctgagt ggctgctggg cctccaccgg gcccccgaga agctgcgcaa
781 actcagcgag atcaacaagt tgctggcgca tcggccatgg ctcatcacca aggaacacat
841 ccaggccttg ctgaagaccg gcgagcacac ttggtccctg gccgagctca ttcaggctct
901 ggtcctgctc acccactgcc actcgctctc ctccttcgtg tttggctgtg gcatcctccc
961 tgagggggat gcagatggca gccctgcccc ccaggcacct acacccccta gtgaacagag
1021 cagcccccca agcagggacc cgttgaacaa ctctgggggc tttgagtctg cccgcgacgt
1081 ggaggcgctg atggagcgca tgcagcagct gcaggagagc ctgctgcggg atgaggggac
1141 gtcccaggag gagatggaga gccgctttga gctggagaag tcagagagcc tgctggtgac
1201 cccctcagct gacatcctgg agccctctcc acacccagac atgctgtgct ttgtggaaga
1261 ccctactttc ggatatgagg acttcactcg gagaggggct caggcacccc ctaccttccg
1321 ggcccaggat tatacctggg aagaccatgg ctactcgctg atccagcggc tttaccctga
1381 gggtgggcag ctgctggatg agaagttcca ggcagcctat agcctcacct acaataccat
1441 cgccatgcac agtggtgtgg acacctccgt gctccgcagg gccatctgga actatatcca
1501 ctgcgtcttt ggcatcagat atgatgacta tgattatggg gaggtgaacc agctcctgga
1561 gcggaacctc aaggtctata tcaagacagt ggcctgctac ccagagaaga ccacccgaag
1621 aatgtacaac ctcttctgga ggcacttccg ccactcagag aaggtccacg tgaacttgct
1681 gctcctggag gcgcgcatgc aagccgctct gctgtacgcc ctccgtgcca tcacccgcta
1741 catgacctga ctcctgagca ggacctgggc ccggttcagc tccccacaag gacttctctg
1801 tctggagaca gccccagacc cttttgtgtc ccatgcccac cctccccacg ctgcagtggg
1861 cttgtgtgtg atgtgcagtc ccgaagccac accctccctt ttcctcactg gaatggacag
1921 ttcattgcac tgactctggg atctcagccc tgctcctggg agctggaaga gcacttggag
1981 atcctaaggg accacaccct tcctccttcc cctgcccaca gaggcagagg gcacaggaaa
2041 gaagccgggc caagctcgga attaatgtgc cacaagtgtt gtggccttcc tgaactggga
2101 agtccctggc tggcccccgg gggagagggg caaatgcctc cgggactgac actccaggca
2161 gctttgcctt ctctcccctg tcatttccag atttcattac ctcctacttg ccattcaccc
2221 atcaatgtga aagtcagggt cacagctggt ctgtgtgtcc agttccctaa aagcctgttc
2281 tgttgggcag cctgaggctg ttgcccgaat cctagttcag ttttttgact tcctttgccc
2341 tttttccctt ttctccatgc ttaatggtgt gaggcgtcag gagagaggcc aagtacataa
2401 aaaaaaaaaa aaa
//