LOCUS BC033680 1624 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens dimethylarginine dimethylaminohydrolase 1, mRNA (cDNA
clone MGC:45161 IMAGE:5189970), complete cds.
ACCESSION BC033680
VERSION BC033680.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1624)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1624)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: m Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6912327.
FEATURES Location/Qualifiers
source 1..1624
/db_xref="H-InvDB:HIT000041899"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45161 IMAGE:5189970"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1624
/gene="DDAH1"
/gene_synonym="DDAH"
/db_xref="GeneID:23576"
/db_xref="MIM:604743"
CDS 100..957
/gene="DDAH1"
/gene_synonym="DDAH"
/codon_start=1
/product="DDAH1 protein"
/protein_id="AAH33680.1"
/db_xref="GeneID:23576"
/db_xref="MIM:604743"
/translation="MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAE
RQHQLYVGVLGSKLGLQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEV
DMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKD
YAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDI
AANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCS
VLINKKVDS"
misc_feature 133..936
/gene="DDAH1"
/gene_synonym="DDAH"
/note="Amidinotransf; Region: Amidinotransferase. This
family contains glycine (EC:2.1.4.1) and inosamine
(EC:2.1.4.2) amidinotransferases, enzymes involved in
creatine and streptomycin biosynthesis respectively. This
family also includes arginine deiminases, EC:3.5.3.6.
These enzymes catalyse the reaction: arginine + H2O <=>
citrulline + NH3. Also found in this family is the
Streptococcus anti tumor glycoprotein"
/db_xref="CDD:pfam02274"
BASE COUNT 493 a 375 c 394 g 362 t
ORIGIN
1 caagaggagc cgacgggcgc tcgcaggctc agcgcgcgct gcccgcggca ggacccggcc
61 gcctccgccg ccgccgccgc ccctaagcct cccgaagcca tggccgggct cggccacccc
121 gccgccttcg gccgggccac ccacgccgtg gtgcgggcgc tacccgagtc gctcggccag
181 cacgcgctga gaagcgccaa gggcgaggag gtggacgtcg cccgcgcgga acggcagcac
241 cagctctacg tgggcgtgct gggcagcaag ctggggctgc aggtggtgga gctgccggcc
301 gacgagagcc ttccggactg cgtcttcgtg gaggacgtgg ccgtggtgtg cgaggagacg
361 gccctcatca cccgacccgg ggcgccgagc cggaggaagg aggttgacat gatgaaagaa
421 gcattagaaa aacttcagct caatatagta gagatgaaag atgaaaatgc aactttagat
481 ggcggagatg ttttattcac aggcagagaa ttttttgtgg gcctttccaa aaggacaaat
541 caacgaggtg ctgaaatctt ggctgatact tttaaggact atgcagtctc cacagtgcca
601 gtggcagatg ggttgcattt gaagagtttc tgcagcatgg ctgggcctaa cctgatcgca
661 attgggtcta gtgaatctgc acagaaggcc cttaagatca tgcaacagat gagtgaccac
721 cgctacgaca aactcactgt gcctgatgac atagcagcaa actgtatata tctaaatatc
781 cccaacaaag ggcacgtctt gctgcaccga accccggaag agtatccaga aagtgcaaag
841 gtttatgaga aactgaagga ccatatgctg atccccgtga gcatgtctga actggaaaag
901 gtggatgggc tgctcacctg ctgctcagtt ttaattaaca agaaagtaga ctcctgagct
961 gcagagtccc ccccggtagc cggcaagacc gcacaggcaa ggccgatgac tctgtgccca
1021 ctcctgttgt tttccttgac aatctgattc aatttagtta aaggatgata tagagaaaat
1081 acattattta gcattatttc ttcagctata atgaattgct atagaaatca ggcagatctt
1141 tctaatgtgt attgattggt cttttcagct actctgaaca gattactaag gccatctcct
1201 catctctaag ggagaaaaat agtctgtaga tgaataatgt aaggtaaaga gttgcatgtc
1261 agtctttgta attatttaca ctttaacttt ctccagaact cagacatgat ttcaacatgg
1321 tgttagattt gtgcatttta ttttcctgac cacctcattc cagccaatgt atggttatcc
1381 actctgtgtg ccaaaaccaa tcatgccttt cacggccctt tagttcagag aagttctgca
1441 ctgattttta gtctcttgat gtctcaatct tacatgtata ccaatcacaa tggaataaag
1501 tgttgagttg tactgtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 aaaa
//