LOCUS BC033640 4615 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens Hermansky-Pudlak syndrome 5, mRNA (cDNA clone
MGC:45180 IMAGE:5502950), complete cds.
ACCESSION BC033640
VERSION BC033640.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4615)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4615)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: g Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31657124.
FEATURES Location/Qualifiers
source 1..4615
/db_xref="H-InvDB:HIT000041880"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45180 IMAGE:5502950"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4615
/gene="HPS5"
/gene_synonym="AIBP63"
/gene_synonym="KIAA1017"
/db_xref="GeneID:11234"
/db_xref="HGNC:HGNC:17022"
/db_xref="MIM:607521"
CDS 425..3472
/gene="HPS5"
/gene_synonym="AIBP63"
/gene_synonym="KIAA1017"
/codon_start=1
/product="Hermansky-Pudlak syndrome 5"
/protein_id="AAH33640.1"
/db_xref="GeneID:11234"
/db_xref="HGNC:HGNC:17022"
/db_xref="MIM:607521"
/translation="MYVSSEHKGRRVTALCWDTAILRVFVGDHAGKVSAIKLNTSKQA
KAAAAFVMFPVQTITTVDSCVVQLDYLDGRLLISSLTRSFLCDTEREKFWKIGNKERD
GEYGACFFPGRCSGGQQPLIYCARPGSRMWEVNFDGEVISTHQFKKLLSLPPLPVITL
RSEPQYDHTAGSSQSLSFPKLLHLSEHCVLTWTERGIYIFIPQNVQVLLWSEVKDIQD
VAVCRNELFCLHLNGKVSHLSLISVERCVERLLRRGLWNLAARTCCLFQNSVIASRAR
KTLTADKLEHLKSQLDHGTYNDLISQLEELILKFEPLDSACSSRRSSISSHESFSILD
SGIYRIISSRRGSQSDEDSCSLHSQTLSEDERFKEFTSQQEEDLPDQCCGSHGNEDNV
SHAPVMFETDKNETFLPFGIPLPFRSPSPLVSLQAVKESVSSFVRKTTEKIGTLHTSP
DLKVRPELRGDEQSCEEDVSSDTCPKEEDTEEEKEVTSPPPEEDRFQELKVATAEAMT
KLQDPLVLFESESLRMVLQEWLSHLEKTFAMKDFSGVSDTDNSSMKLNQDVLLVNESK
KGILDEDNEKEKRDSLGNEESVDKTACECVRSPRESLDDLFQICSPCAIASGLRNDLA
ELTTLCLELNVLNSKIKSTSGHVDHTLQQYSPEILACQFLKKYFFLLNLKRAKESIKL
SYSNSPSVWDTFIEGLKEMASSNPVYMEMEKGDLPTRLKLLDDEVPFDSPLLVVYATR
LYEKFGESALRSLIKFFPSILPSDIIQLCHHHPAEFLAYLDSLVKSRPEDQRSSFLES
LLQPESLRLDWLLLAVSLDAPPSTSTMDDEGYPRPHSHLLSWGYSQLILHLIKLPADF
ITKEKMTDICRSCGFWPGYLILCLELERRREAFTNIVYLNDMSLMKGDNGWIPETVEE
WKLLLHLIQSKSTRPAPQESLNGSLSDGPSPINVENVALLLAKAMGPDRAWSLLQECG
LALELSEKFTRTCDILRIAEKRQRALIQSMLEKCDRFLWSQQA"
BASE COUNT 1333 a 895 c 1052 g 1335 t
ORIGIN
1 ccacgcgtcc gcccggcgct aagccgggag acaagatccg atctactgag agctgcgagg
61 tactgccctg gatgtggtgg agctgggctg ggacctccgg gctgctggtc tgtgagcctg
121 gctttgaaaa ttggttactg ggtctcctct caagaaatct caagatatta aagttactgc
181 tgttaaaaag tgcacgagca tagctgtgtc tcggaaatgg ttggctttgg gcagttcagg
241 aggaggactc catctcattc agaaagaagg ctggaagcac aggctttttc tttcacacag
301 ggaaggtgca atttctcaag tcgcctgttg tttacatgat gatgattatg ttgctgtagc
361 taccagtcaa ggtcttgtgg ttgtttggga attaaatcaa gagcgtcgtg ggaaaccgga
421 acaaatgtat gtgtcttcag aacacaaagg ccgaagagtc acagctctct gctgggatac
481 agctattctt agagtttttg taggtgatca tgctgggaag gtttctgcta tcaaactcaa
541 tacttctaaa caagcaaagg cagctgctgc ttttgtgatg tttcctgttc agacaatcac
601 aactgttgac tcctgtgttg tacagttaga ttatttggat ggaaggctac ttatatcttc
661 acttactcga tccttcttgt gtgacactga gagagaaaag ttttggaaaa ttggaaacaa
721 ggaaagagat ggagaatatg gagcttgttt ctttcctgga agatgttctg ggggccagca
781 acctctgata tattgtgctc gcccaggctc taggatgtgg gaagtgaact ttgatggaga
841 agttataagt acacatcagt tcaagaaact cctctcgttg ccacctctcc ctgtgattac
901 tctaagatca gaacctcagt atgatcatac agctggatcc tcccagtctt tgtctttccc
961 caaactctta catcttagtg agcattgtgt gctgacttgg acagaaagag gaatttatat
1021 tttcattcct cagaatgttc aagttcttct ttggagtgaa gtcaaagata ttcaggatgt
1081 ggctgtctgt aggaatgaat tgttctgttt gcacctaaat gggaaagtct cacatctctc
1141 cctgatatct gtggagcgct gtgtggaacg cctgctaaga agaggcctat ggaacttggc
1201 tgctcgtaca tgctgtcttt tccaaaattc tgtcattgcc agcagagcaa gaaaaacttt
1261 gactgcagat aaattggagc atttgaaatc tcagctggac catggcacct acaatgatct
1321 aatttctcaa ctggaagaat tgatcttaaa atttgaacct ttggattcag cttgtagcag
1381 tagaagaagc tccatttcat cacatgaaag tttcagcatc ttggactctg gtatttatcg
1441 tatcattagt agtagaagag gcagtcagtc agatgaagac tcttgctccc ttcacagcca
1501 aaccctctca gaagatgaga gatttaaaga attcacctca cagcaggaag aggacctgcc
1561 agatcagtgt tgtggctcac acggaaatga agacaatgtt tctcatgctc cagtgatgtt
1621 tgagacagat aagaatgaaa cttttctccc gttcggcatt ccattaccat ttcgttctcc
1681 atctcctctt gtgtctcttc aggctgtcaa agaaagtgtt tctagctttg tgcgtaaaac
1741 tactgagaag attggcaccc ttcacacgag ccctgatctg aaagtgagac cagagctcag
1801 gggtgatgag caatcatgtg aagaggatgt gagttcagat acctgcccaa aggaggaaga
1861 cactgaggag gaaaaagagg taactagtcc acctccagaa gaagacaggt tccaggagct
1921 taaagtagca acagcagaag caatgaccaa gctacaggac cctctggttt tatttgaatc
1981 cgagtctctg agaatggttt tacaggagtg gctttcacat ttagaaaaaa catttgccat
2041 gaaggacttt tcaggtgttt cagatactga caactcatcc atgaaattga accaggatgt
2101 gctattagtt aatgaatcaa aaaagggaat attagatgaa gataatgaaa aagaaaaaag
2161 ggactcttta ggcaatgaag aatctgttga taaaacagca tgtgaatgtg taaggagtcc
2221 aagggagtct ttggatgacc tgtttcaaat atgttctcca tgcgccattg caagtggtct
2281 tcggaacgac ctggctgaat tgacaacatt atgtttggag ttgaatgtat tgaattctaa
2341 gatcaaaagc accagtggac atgtggacca cactttgcaa cagtactctc ctgaaattct
2401 ggcttgccag ttcctgaaga agtacttttt tctcctgaac ttgaaaagag cgaaggagag
2461 tatcaagctt agttacagta atagcccttc tgtttgggat acttttattg aaggattgaa
2521 agaaatggca agttccaatc ctgtgtatat ggagatggaa aaaggagatc taccaacaag
2581 gttaaagtta ctagatgacg aggttccttt tgatagtccg ttgttggttg tttatgctac
2641 ccggttgtat gaaaagtttg gggagtctgc tcttcgatcc ttaatcaagt tctttccatc
2701 cattttgcca tcggatatca tacaactttg tcatcatcat cctgctgagt ttttggccta
2761 tttagacagt ctggtgaaat caaggcctga agatcagcgg tcatcttttc ttgagtccct
2821 tctgcaacca gagtctttaa ggttggattg gctgcttttg gcagtgtccc ttgatgctcc
2881 accaagcacc agcacaatgg atgatgaagg ttatcccagg cctcattcac acttgctttc
2941 ctggggttac agtcagctga tccttcatct aattaaactt cctgcagatt ttataaccaa
3001 agagaaaatg acagacatct gcaggtcttg tggtttctgg cctggatatc taattctctg
3061 tttggagctg gagagaagaa gagaggcctt caccaatatt gtgtatctga atgatatgag
3121 cctgatgaaa ggggacaatg gttggatccc agagaccgtg gaggaatgga agcttctcct
3181 tcatctcata cagagcaaga gcacgaggcc agccccccag gagtcactaa atgggagcct
3241 cagtgatggg ccttccccca tcaatgtgga gaatgtggca cttctgttag ctaaggccat
3301 gggcccagat cgggcttggt cactgctaca ggaatgtggt ctggcccttg agttgtcaga
3361 gaagtttacc agaacctgcg atatcctgag gattgctgag aaaaggcaga gggccttgat
3421 acaaagcatg cttgaaaaat gcgatcggtt tctctggtcc cagcaggcct agtgggagaa
3481 gattcagcag gatgtcatga cattttgaga aaaactaaat catgctcctg aaccttctga
3541 acgcatttgt tattgaagga aagacaccac ccccaaatcc tgccatctta ttggggctac
3601 ttttgtcagt gtctgtaccc ttggcatcgg catctgtgac tctttatcca tgacctcagt
3661 gtttcttaac caaagttgta ctcagcattt cttaaccaaa gttgaatttt gaaaagagtc
3721 agtccttgtt tgctggaatt agaatgttaa tgtcctagta ttattccgaa ctacagtatt
3781 aactgcttgt tgctagtgga ttagacagat tcttttctta ctgtggcttc catgttggga
3841 gcagaagctt ttcatcctgg tcacatgaag acagatggta ttattgactg gagttgaatt
3901 atttttatat cttgtctggc acaatatgga aattaatgaa ataagacggt gtataatgga
3961 attaacaccc aaaataagta gaacactgaa gatttgaatt tgatatttaa gtaaaatggg
4021 actgggtgca gtggctcagg cctgtaatcc caaccctttg gaaggtaaag acgggaggat
4081 cacttgaggc caggagttca agaccagcct gggcaacata gtgagaatgc atctctacaa
4141 aaaataaaaa aaattagcta ggcatagtac ctgaggccag gaggtccagg ccgcaatgag
4201 atgtgtttgt gccattgcac accagtctgg gtgacagaga aagaccctgt ctcaaaaaca
4261 aattaaataa aatatcttca tatataaatt aagctaatta aaaatatttt tccctgtatt
4321 tatttaatat tttctaatct gaacccatat acagctgact aattcattct tagaaatgtg
4381 ttatctgtaa tctttcctaa acagagtagc ccacaagaat catgcacttt ttaaaattat
4441 ttctaagaag ccataacaaa gctgtgtact aataaagact gcagcaagca cttgtgttat
4501 ttaaattatg taagtagatt gtcatttgtc aggctcctgt acatttacat agcatgttat
4561 attaataata aatgtaaaat atgactaaag ttttcattgg aaaaaaaaaa aaaaa
//