LOCUS BC033639 2468 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens cholinergic receptor, nicotinic, alpha 5, mRNA (cDNA
clone MGC:45360 IMAGE:5501542), complete cds.
ACCESSION BC033639
VERSION BC033639.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2468)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2468)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: g Column: 12.
FEATURES Location/Qualifiers
source 1..2468
/db_xref="H-InvDB:HIT000041879"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45360 IMAGE:5501542"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2468
/gene="CHRNA5"
/db_xref="GeneID:1138"
/db_xref="HGNC:HGNC:1959"
/db_xref="MIM:118505"
CDS 163..1569
/gene="CHRNA5"
/codon_start=1
/product="cholinergic receptor, nicotinic, alpha 5"
/protein_id="AAH33639.1"
/db_xref="GeneID:1138"
/db_xref="HGNC:HGNC:1959"
/db_xref="MIM:118505"
/translation="MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIA
KHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQE
WIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTW
TPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEW
EIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPS
NEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFA
INIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSHVDRYFTQKEETESGSGPKSSRNT
LEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPV
IYKWANILIPVHIGNANK"
BASE COUNT 717 a 495 c 548 g 708 t
ORIGIN
1 ccacgcgtcc gggcgggagc tgtggcgcgg agcggcccct ctgctgcgtc tgccctcgtt
61 ttgtctcacg actcacactc agtgctccat tccccaagag ttcgcgttcc ccgcgcggcg
121 gtcgagaggc ggctgcccgc ggtcccgcgc gggcgcgggg cgatggcggc gcgggggtca
181 gggccccgcg cgctccgcct gctgctcttg gtccagctgg tcgcggggcg ctgcggtcta
241 gcgggcgcgg cgggcggcgc gcagagagga ttatctgaac cttcttctat tgcaaaacat
301 gaagatagtt tgcttaagga tttatttcaa gactacgaaa gatgggttcg tcctgtggaa
361 cacctgaatg acaaaataaa aataaaattt ggacttgcaa tatctcaatt ggtggatgtg
421 gatgagaaaa atcagttaat gacaacaaac gtctggttga aacaggaatg gatagatgta
481 aaattaagat ggaaccctga tgactatggt ggaataaaag ttatacgtgt tccttcagac
541 tctgtctgga caccagacat cgttttgttt gataatgcag atggacgttt tgaagggacc
601 agtacgaaaa cagtcatcag gtacaatggc actgtcacct ggactccacc ggcaaactac
661 aaaagttcct gtaccataga tgtcacgttt ttcccatttg accttcagaa ctgttccatg
721 aaatttggtt cttggactta tgatggatca caggttgata taattctaga ggaccaagat
781 gtagacaaga gagatttttt tgataatgga gaatgggaga ttgtgagtgc aacagggagc
841 aaaggaaaca gaaccgacag ctgttgctgg tatccgtatg tcacttactc atttgtaatc
901 aagcgcctgc ctctctttta taccttgttc cttataatac cctgtattgg gctctcattt
961 ttaactgtac ttgtcttcta tcttccttca aatgaaggtg aaaagatttg tctctgcact
1021 tcagtacttg tgtctttgac tgtcttcctt ctggttattg aagagatcat accatcatct
1081 tcaaaagtca tacctctaat tggagagtat ctggtattta ccatgatttt tgtgacactg
1141 tcaattatgg taaccgtctt cgctatcaac attcatcatc gttcttcctc aacacataat
1201 gccatggcgc ctttggtccg caagatattt cttcacacgc ttcccaaact gctttgcatg
1261 agaagtcatg tagacaggta cttcactcag aaagaggaaa ctgagagtgg tagtggacca
1321 aaatcttcta gaaacacatt ggaagctgcg ctcgattcta ttcgctacat tacaagacac
1381 atcatgaagg aaaatgatgt ccgtgaggtt gttgaagatt ggaaattcat agcccaggtt
1441 cttgatcgga tgtttctgtg gacttttctt ttcgtttcaa ttgttggatc tcttgggctt
1501 tttgttcctg ttatttataa atgggcaaat atattaatac cagttcatat tggaaatgca
1561 aataagtgaa gcctcccaag ggactgaagt atacatttag ttaacacaca tatatctgat
1621 ggcacctata aaattatgaa aatgtaagtt atgtgttaaa tttagtgcaa gctttaacag
1681 actaagttgc taacctcaat ttatgttaac agatgatcca tttgaacagt tggctgtatg
1741 actgaagtaa taactgatga gatacatttg atcttgtaaa aatagcaaaa tattatctga
1801 actggactag tgaaaaatct agtatttgta tcctggcaaa taatactaat ttataatcca
1861 cagtaaagtt catcctttga ctgtgctgga gaattccagt tgtatttgaa gactgatttt
1921 aaaacttttc tgcatttggt aaaggtatgt aaactttcct gtactcactg agtaacagct
1981 aatctttaat ataatattat actgctatat ttaaaaagct gactacttga tataattact
2041 taatgtgatg cttgatataa taattactta atgtggccgg gcacggtggc tcacacctgt
2101 aatcccagca ctttgggagg tcgaggtggg cgtatcacct gaggttggga gttcgagacc
2161 agcctgacca acgtggagaa accccgtctc tactaaaaat atgaaattag ccagggtggt
2221 ggtgcacacc tgtaatccca gctacctggg aggctgcggc aggagaatcg cttgaaccca
2281 ggtggcggag gttgcggtga gctgagatca cgccattgca ctccagcctg ggcaacaaga
2341 gcaaaactca gtctcaaata ataataataa caacaactta atgtgctgct gcttttccat
2401 aaccaacatt ttaaaaataa atgaaaaaca ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2461 aaaaaaaa
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