LOCUS BC033622 2520 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens IMP (inosine monophosphate) dehydrogenase 1, mRNA
(cDNA clone MGC:40351 IMAGE:5210847), complete cds.
ACCESSION BC033622
VERSION BC033622.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2520)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2520)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: j Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34328927.
FEATURES Location/Qualifiers
source 1..2520
/db_xref="H-InvDB:HIT000041870"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40351 IMAGE:5210847"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2520
/gene="IMPDH1"
/gene_synonym="IMPD"
/gene_synonym="IMPD1"
/gene_synonym="sWSS2608"
/db_xref="GeneID:3614"
/db_xref="HGNC:HGNC:6052"
/db_xref="MIM:146690"
CDS 73..1764
/gene="IMPDH1"
/gene_synonym="IMPD"
/gene_synonym="IMPD1"
/gene_synonym="sWSS2608"
/codon_start=1
/product="IMP (inosine monophosphate) dehydrogenase 1"
/protein_id="AAH33622.2"
/db_xref="GeneID:3614"
/db_xref="HGNC:HGNC:6052"
/db_xref="MIM:146690"
/translation="MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAG
YEPESMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTS
ALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFE
QGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEK
DHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDL
KKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA
MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQ
GTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYF
FSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPY
LIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY"
BASE COUNT 518 a 794 c 742 g 466 t
ORIGIN
1 ggctgcgctc actgcccagc cggggccccg ggagcctcca ggctcccgcc cgccctgagc
61 tgcggcctcc gcatggaggg gccactcact ccaccaccgc tgcagggagg cggagccgcc
121 gctgttccgg agcccggagc ccggcaacac ccgggacacg agacggcggc gcagcggtac
181 agcgcccgac tgctgcaggc cggctacgag cccgagagca tggcggacta cctgatcagc
241 ggcggcaccg gctacgtgcc cgaggatggg ctcaccgcgc agcagctctt cgccagcgcc
301 gacggcctca cctacaacga cttcctgatt ctcccaggat tcatagactt catagctgat
361 gaggtggacc tgacctcagc cctgacccgg aagatcacgc tgaagacgcc actgatctcc
421 tcccccatgg acactgtgac agaggctgac atggccattg ccatggctct gatgggaggt
481 attggtttca ttcaccacaa ctgcacccca gagttccagg ccaacgaggt gcggaaggtc
541 aagaagtttg aacagggctt catcacggac cctgtggtgc tgagcccctc gcacactgtg
601 ggcgatgtgc tggaggccaa gatgcggcat ggcttctctg gcatccccat cactgagacg
661 ggcaccatgg gcagcaagct ggtgggcatc gtcacctccc gagacatcga ctttcttgct
721 gagaaggacc acaccaccct cctcagtgag gtgatgacgc caaggattga actggtggtg
781 gctccagcag gtgtgacgtt gaaagaggca aatgagatcc tgcagcgtag caagaaaggg
841 aagctgccta tcgtcaatga ttgcgatgag ctggtggcca tcatcgcccg caccgacctg
901 aagaagaacc gagactaccc tctggcctcc aaggattccc agaagcagct cctctgtggg
961 gcagctgtgg gcacccgtga ggatgacaaa taccgtctgg acctgctcac ccaggcgggc
1021 gtcgacgtca tagtcttgga ctcgtcccaa gggaattcgg tgtatcagat cgccatggtg
1081 cattacatca aacagaagta cccccacctc caggtgattg gggggaacgt ggtgacagca
1141 gcccaggcca agaacctgat tgatgctggt gtggacgggc tgcgcgtggg catgggctgc
1201 ggctccatct gcatcaccca ggaagtgatg gcctgtggtc ggccccaggg cactgctgtg
1261 tacaaggtgg ctgagtatgc ccggcgcttt ggtgtgccca tcatagccga tggcggcatc
1321 cagaccgtgg gacacgtggt caaggccctg gcccttggag cctccacagt gatgatgggc
1381 tccctgctgg ccgccactac ggaggcccct ggcgagtact tcttctcaga cggggtgcgg
1441 ctcaagaagt accggggcat gggctcactg gatgccatgg agaagagcag cagcagccag
1501 aaacgatact tcagcgaggg ggataaagtg aagatcgcgc agggtgtctc gggctccatc
1561 caggacaaag gatccattca gaagttcgtg ccctacctca tagcaggcat ccaacacggc
1621 tgccaggata tcggggcccg cagcctgtct gtccttcggt ccatgatgta ctcaggagag
1681 ctcaagtttg agaagcggac catgtcggcc cagattgagg gtggtgtcca tggcctgcac
1741 tcttacgaaa agcggctgta ctgaggacag cggtggaggc cgaggtggtg gaggggatgc
1801 accccagtgt ccacttttgg gcacagcctc cctccataac tgagtggtcc acagatttgc
1861 actacgggtt ctccagctcc tttccaggca gagaggaggg gaggtcctga ggggactgct
1921 gcccctcact cggcatcccc tgcagagtca ggactgctcc cggggccagg ctgccctggg
1981 agcccccctc cgagcccagc cagccaggct ctcaggccct gcgcctgcct caggtctttc
2041 ttgctgcagc ctgctccagc ctggccccca ccccaggggc aggcggcccc tcctggcttc
2101 tcctgtaggg cacctccctg cccctagcct cccaggaaat ggtgctctcc tggccctgcc
2161 tctggccctt cccgggccgc tgcccctcag ccatgtggca cttctgagct cctgacctag
2221 gccaagggga ggtctctgcc cccttccccg gccctgggct acccttgggt cctgctcctc
2281 aggccgctcc cctgtccctg gccatgggta ggagactgcc ctggtcatgg ccgcctgcct
2341 gtcattcctg actcaccacc gtccccaggt gaaccattcc tcccttctcc tcagctgcag
2401 tcgaaggctt taactttgca cacttgggat cacagttgcg tcattgtgta ttaaatactt
2461 ggaataaatc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//