LOCUS BC033507 1971 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens desert hedgehog homolog (Drosophila), mRNA (cDNA clone
MGC:35145 IMAGE:5169286), complete cds.
ACCESSION BC033507
VERSION BC033507.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1971)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1971)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 51 Row: b Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23346635.
FEATURES Location/Qualifiers
source 1..1971
/db_xref="H-InvDB:HIT000051127"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:35145 IMAGE:5169286"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1971
/gene="DHH"
/gene_synonym="HHG-3"
/gene_synonym="MGC35145"
/db_xref="GeneID:50846"
/db_xref="HGNC:HGNC:2865"
/db_xref="MIM:605423"
CDS 308..1498
/gene="DHH"
/gene_synonym="HHG-3"
/gene_synonym="MGC35145"
/codon_start=1
/product="desert hedgehog homolog (Drosophila)"
/protein_id="AAH33507.1"
/db_xref="GeneID:50846"
/db_xref="HGNC:HGNC:2865"
/db_xref="MIM:605423"
/translation="MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLL
YKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTER
CKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYG
LLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRE
LHRGDWVLAADASGRVVPTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAA
RGPAPAPGDFAPVFARRLRAGDSVLAPGGDALRPARVARVAREEAVGVFAPLTAHGTL
LVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPGGAVQPTGMHWYSRLLYRLAE
ELLG"
BASE COUNT 372 a 570 c 660 g 369 t
ORIGIN
1 gtccggagtc cgggcgttct ggcagcacca gagtcctgca gcagagacgg gctgggctgg
61 cactcaccca cgacccccct tccctgctat gatggtttgt cagtagcagg tcctagacac
121 cccccgcccg ctcccggggc acgtgggcag agctagcagc agccaggtgc acggagccac
181 aagagctcta gggcactctg ggggcagctg tgcctgctgc cctctctggt gcctgtggag
241 atgcctaact gacaggagag ttagtgagga caagaacgct cccttttggc cgaggtccgc
301 tgtatccatg gctctcctga ccaatctact gcccctgtgc tgcttggcac ttctggcgct
361 gccagcccag agctgcgggc cgggccgggg gccggttggc cggcgccgct atgcgcgcaa
421 gcagctcgtg ccgctactct acaagcaatt tgtgcccggc gtgccagagc ggaccctggg
481 cgccagtggg ccagcggagg ggagggtggc aaggggctcc gagcgcttcc gggacctcgt
541 gcccaactac aaccccgaca tcatcttcaa ggatgaggag aacagtggag ccgaccgcct
601 gatgaccgag cgttgtaagg agcgggtgaa cgctttggcc attgccgtga tgaacatgtg
661 gcccggagtg cgcctacgag tgactgaggg ctgggacgag gacggccacc acgctcagga
721 ttcactccac tacgaaggcc gtgctttgga catcactacg tctgaccgcg accgcaacaa
781 gtatgggttg ctggcgcgcc tcgcagtgga agccggcttc gactgggtct actacgagtc
841 ccgcaaccac gtccacgtgt cggtcaaagc tgataactca ctggcggtcc gggcgggcgg
901 ctgctttccg ggaaatgcaa ctgtgcgcct gtggagcggc gagcggaaag ggctgcggga
961 actgcaccgc ggagactggg ttttggcggc cgatgcgtca ggccgggtgg tgcccacgcc
1021 ggtgctgctc ttcctggacc gggacttgca gcgccgggct tcatttgtgg ctgtggagac
1081 cgagtggcct ccacgcaaac tgttgctcac gccctggcac ctggtgtttg ccgctcgagg
1141 gccggcgccc gcgccaggcg actttgcacc ggtgttcgcg cgccggctac gcgctgggga
1201 ctcggtgctg gcgcccggcg gggatgcgct tcggccagcg cgcgtggccc gtgtggcgcg
1261 ggaggaagcc gtgggcgtgt tcgcgccgct caccgcgcac gggacgctgc tggtgaacga
1321 tgtcctggcc tcttgctacg cggttctgga gagtcaccag tgggcgcacc gcgcttttgc
1381 ccccttgaga ctgctgcacg cgctaggggc gctgctcccc ggcggggccg tccagccgac
1441 tggcatgcat tggtactctc ggctcctcta ccgcttagcg gaggagctac tgggctgagc
1501 gtcccaggca tagaaacctc gaagcgcccg aggaaacgag ggcctgctgg ctgagatatg
1561 gggctgtggg cagcagacga tgccgactgg aagggaggga gagggagggg gagggagaaa
1621 atggggctat gcctggctta ggggcaacct cgtactgaga ggaggtgata ccgggtccta
1681 ggtaggtagg gctgatggtg cgcactcctt aaagaggact atttagcctc tcccccagtg
1741 cttcagcccc acccgataat tttattttat ttcttattta taaattgtaa tataatgatt
1801 cccttgccca gcttgccaag gtgaggggct ggggcatggc attaacactg tctgacacag
1861 ccagccagtc tgacatctga cgttttcctg caaggtgggc taataaaggg aaggctttca
1921 ggagcttact ggaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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