LOCUS       BC033298                 389 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens defensin, beta 1, mRNA (cDNA clone MGC:24835
            IMAGE:4775720), complete cds.
ACCESSION   BC033298
VERSION     BC033298.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 389)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUN-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: James Cleaver, M.D.
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Baylor College of Medicine Human Genome
            Sequencing Center
            Center code: BCM-HGSC
            Web site: http://www.hgsc.bcm.tmc.edu/cdna/
            Contact: amg@bcm.tmc.edu
            Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
            Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
            A.N., Gibbs, R.A.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 29 Row: k Column: 24
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 50659096.
FEATURES             Location/Qualifiers
     source          1..389
                     /db_xref="H-InvDB:HIT000051106"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:24835 IMAGE:4775720"
                     /tissue_type="Skin, normal"
                     /clone_lib="NCI_CGAP_Skn3"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6.1"
     gene            1..389
                     /gene="DEFB1"
                     /gene_synonym="BD1"
                     /gene_synonym="DEFB-1"
                     /gene_synonym="DEFB101"
                     /gene_synonym="HBD1"
                     /gene_synonym="MGC51822"
                     /db_xref="GeneID:1672"
                     /db_xref="HGNC:HGNC:2766"
                     /db_xref="MIM:602056"
     CDS             61..267
                     /gene="DEFB1"
                     /gene_synonym="BD1"
                     /gene_synonym="DEFB-1"
                     /gene_synonym="DEFB101"
                     /gene_synonym="HBD1"
                     /gene_synonym="MGC51822"
                     /codon_start=1
                     /product="defensin, beta 1"
                     /protein_id="AAH33298.1"
                     /db_xref="GeneID:1672"
                     /db_xref="HGNC:HGNC:2766"
                     /db_xref="MIM:602056"
                     /translation="MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQC
                     LYSACPIFTKIQGTCYRGKAKCCK"
BASE COUNT          124 a           83 c           82 g          100 t
ORIGIN      
        1 ctccaaagga gccagcgtct ccccagttcc tgaaatcctg ggtgttgcct gccagtcgcc
       61 atgagaactt cctaccttct gctgtttact ctctgcttac ttttgtctga gatggcctca
      121 ggtggtaact ttctcacagg ccttggccac agatctgatc attacaattg cgtcagcagt
      181 ggagggcaat gtctctattc tgcctgcccg atctttacca aaattcaagg cacctgttac
      241 agagggaagg ccaagtgctg caagtgagct gggagtgacc agaagaaatg acgcagaagt
      301 gaaatgaact ttttataagc attcttttaa taaaggaaaa ttgcttttga agtataaaaa
      361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//