LOCUS BC033097 2368 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens heparin-binding EGF-like growth factor, mRNA (cDNA
clone MGC:45671 IMAGE:5424240), complete cds.
ACCESSION BC033097
VERSION BC033097.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2368)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2368)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 43 Row: l Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503412.
FEATURES Location/Qualifiers
source 1..2368
/db_xref="H-InvDB:HIT000041799"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45671 IMAGE:5424240"
/tissue_type="Eye, normal, pigmented retinal epithelium"
/clone_lib="NIH_MGC_43"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2368
/gene="HBEGF"
/gene_synonym="DTSF"
/db_xref="GeneID:1839"
/db_xref="HGNC:HGNC:3059"
/db_xref="MIM:126150"
CDS 263..889
/gene="HBEGF"
/gene_synonym="DTSF"
/codon_start=1
/product="heparin-binding EGF-like growth factor"
/protein_id="AAH33097.1"
/db_xref="GeneID:1839"
/db_xref="HGNC:HGNC:3059"
/db_xref="MIM:126150"
/translation="MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPT
VSTDQLLPLGGGRDRKVRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLG
KKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHT
TILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGMTNSH"
BASE COUNT 606 a 580 c 605 g 577 t
ORIGIN
1 agctacgcgg gccacgctgc tggctggcct gacctaggcg cgcggggtcg ggcggccgcg
61 cgggcgggct gagtgagcaa gacaagacac tcaagaagag cgagctgcgc ctgggtcccg
121 gccaggcttg cacgcagagg cgggcggcag acggtgcccg gcggaatctc ctgagctccg
181 ccgcccagct ctggtgccag cgcccagtgg ccgccgcttc gaaagtgact ggtgcctcgc
241 cgcctcctct cggtgcggga ccatgaagct gctgccgtcg gtggtgctga agctctttct
301 ggctgcagtt ctctcggcac tggtgactgg cgagagcctg gagcggcttc ggagagggct
361 agctgctgga accagcaacc cggaccctcc cactgtatcc acggaccagc tgctacccct
421 aggaggcggc cgggaccgga aagtccgtga cttgcaagag gcagatctgg accttttgag
481 agtcacttta tcctccaagc cacaagcact ggccacacca aacaaggagg agcacgggaa
541 aagaaagaag aaaggcaagg ggctagggaa gaagagggac ccatgtcttc ggaaatacaa
601 ggacttctgc atccatggag aatgcaaata tgtgaaggag ctccgggctc cctcctgcat
661 ctgccacccg ggttaccatg gagagaggtg tcatgggctg agcctcccag tggaaaatcg
721 cttatatacc tatgaccaca caaccatcct ggccgtggtg gctgtggtgc tgtcatctgt
781 ctgtctgctg gtcatcgtgg ggcttctcat gtttaggtac cataggagag gaggttatga
841 tgtggaaaat gaagagaaag tgaagttggg catgactaat tcccactgag agagacttgt
901 gctcaaggaa tcggctgggg actgctacct ctgagaagac acaaggtgat ttcagactgc
961 agaggggaaa gacttccatc tagtcacaaa gactccttcg tccccagttg ccgtctagga
1021 ttgggcctcc cataattgct ttgccaaaat accagagcct tcaagtgcca aacagagtat
1081 gtccgatggt atctgggtaa gaagaaagca aaagcaaggg accttcatgc ccttctgatt
1141 cccctccacc aaaccccact tcccctcata agtttgttta aacacttatc ttctggatta
1201 gaatgccggt taaattccat atgctccagg atctttgact gaaaaaaaaa aagaagaaga
1261 agaaggagag caagaaggaa agatttgtga actggaagaa agcaacaaag attgagaagc
1321 catgtactca agtaccacca agggatctgc cattgggacc ctccagtgct ggatttgatg
1381 agttaactgt gaaataccac aagcctgaga actgaatttt gggacttcta cccagatgga
1441 aaaataacaa ctatttttgt tgttgttgtt tgtaaatgcc tcttaaatta tatatttatt
1501 ttattctatg tatgttaatt tatttagttt ttaacaatct aacaataata tttcaagtgc
1561 ctagactgtt actttggcaa tttcctggcc ctccactcct catccccaca atctggctta
1621 gtgccaccca cctttgccac aaagctagga tggttctgtg acccatctgt agtaatttat
1681 tgtctgtcta catttctgca gatcttccgt ggtcagagtg ccactgcggg agctctgtat
1741 ggtcaggatg taggggttaa cttggtcaga gccactctat gagttggact tcagtcttgc
1801 ctaggcgatt ttgtctacca tttgtgtttt gaaagcccaa ggtgctgatg tcaaagtgta
1861 acagatatca gtgtctcccc gtgtcctctc cctgccaagt ctcagaagag gttgggcttc
1921 catgcctgta gctttcctgg tccctcaccc ccatggcccc aggcccacag cgtgggaact
1981 cactttccct tgtgtcaaga catttctcta actcctgcca ttcttctggt gctactccat
2041 gcaggggtca gtgcagcaga ggacagtctg gagaaggtat tagcaaagca aaaggctgag
2101 aaggaacagg gaacattgga gctgactgtt cttggtaact gattacctgc caattgctac
2161 cgagaaggtt ggaggtgggg aaggctttgt ataatcccac ccacctcacc aaaacgatga
2221 aggtatgctg tcatggtcct ttctggaagt ttctggtgcc atttctgaac tgttacaact
2281 tgtatttcca aacctggttc atatttatac tttgcaatcc aaataaagat aacccttatt
2341 ccataaaaaa aaaaaaaaaa aaaaaaaa
//