LOCUS BC033092 2465 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens signal-regulatory protein alpha, mRNA (cDNA clone
MGC:45658 IMAGE:4589298), complete cds.
ACCESSION BC033092
VERSION BC033092.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2465)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2465)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 43 Row: f Column: 7.
FEATURES Location/Qualifiers
source 1..2465
/db_xref="H-InvDB:HIT000041795"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45658 IMAGE:4589298"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2465
/gene="SIRPA"
/gene_synonym="BIT"
/gene_synonym="CD172A"
/gene_synonym="MFR"
/gene_synonym="MYD-1"
/gene_synonym="P84"
/gene_synonym="SHPS-1"
/gene_synonym="SHPS1"
/gene_synonym="SIRP"
/gene_synonym="SIRP-ALPHA-1"
/gene_synonym="SIRPalpha"
/gene_synonym="SIRPalpha2"
/db_xref="GeneID:140885"
/db_xref="HGNC:HGNC:9662"
/db_xref="MIM:602461"
CDS 21..1547
/gene="SIRPA"
/gene_synonym="BIT"
/gene_synonym="CD172A"
/gene_synonym="MFR"
/gene_synonym="MYD-1"
/gene_synonym="P84"
/gene_synonym="SHPS-1"
/gene_synonym="SHPS1"
/gene_synonym="SIRP"
/gene_synonym="SIRP-ALPHA-1"
/gene_synonym="SIRPalpha"
/gene_synonym="SIRPalpha2"
/codon_start=1
/product="SIRPA protein"
/protein_id="AAH33092.1"
/db_xref="GeneID:140885"
/db_xref="HGNC:HGNC:9662"
/db_xref="MIM:602461"
/translation="MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVL
VAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNM
DFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARA
TPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLT
REDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVR
KFYPQRLQLTWLENGNVSRTETASTVTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVE
HDGQPAVSKSHDLKVSAHPKEQGSNTAAENTGSNERNIYIVVGVVCTLLVALLMAALY
LVRIRQKKAQGSTSSTRLHEPEKNAREITQVQSLDTNDITYADLNLPKGKKPAPQAAE
PNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQVPRK
"
BASE COUNT 621 a 776 c 635 g 433 t
ORIGIN
1 gggcggcgca gccgcggccc atggagcccg ccggcccggc ccccggccgc ctcgggccgc
61 tgctctgcct gctgctcgcc gcgtcctgcg cctggtcagg agtggcgggt gaggaggagc
121 tgcaggtgat tcagcctgac aagtccgtgt tggttgcagc tggagagaca gccactctgc
181 gctgcactgc gacctctctg atccctgtgg ggcccatcca gtggttcaga ggagctggac
241 caggccggga attaatctac aatcaaaaag aaggccactt cccccgggta acaactgttt
301 cagacctcac aaagagaaac aacatggact tttccatccg catcggtaac atcaccccag
361 cagatgccgg cacctactac tgtgtgaagt tccggaaagg gagccccgat gacgtggagt
421 ttaagtctgg agcaggcact gagctgtctg tgcgcgccaa accctctgcc cccgtggtat
481 cgggccctgc ggcgagggcc acacctcagc acacagtgag cttcacctgc gagtcccacg
541 gcttctcacc cagagacatc accctgaaat ggttcaaaaa tgggaatgag ctctcagact
601 tccagaccaa cgtggacccc gtaggagaga gcgtgtccta cagcatccac agcacagcca
661 aggtggtgct gacccgcgag gacgttcact ctcaagtcat ctgcgaggtg gcccacgtca
721 ccttgcaggg ggaccctctt cgtgggactg ccaacttgtc tgagaccatc cgagttccac
781 ccaccttgga ggttactcaa cagcccgtga gggcagagaa ccaggtgaat gtcacctgcc
841 aggtgaggaa gttctacccc cagagactac agctgacctg gttggagaat ggaaacgtgt
901 cccggacaga aacggcctca accgttacag agaacaagga tggtacctac aactggatga
961 gctggctcct ggtgaatgta tctgcccaca gggatgatgt gaagctcacc tgccaggtgg
1021 agcatgacgg gcagccagcg gtcagcaaaa gccatgacct gaaggtctca gcccacccga
1081 aggagcaggg ctcaaatacc gccgctgaga acactggatc taatgaacgg aacatctata
1141 ttgtggtggg tgtggtgtgc accttgctgg tggccctact gatggcggcc ctctacctcg
1201 tccgaatcag acagaagaaa gcccagggct ccacttcttc tacaaggttg catgagcccg
1261 agaagaatgc cagagaaata acacaggtac agtccttgga cacaaatgat atcacatatg
1321 cagacctgaa cctgcccaag gggaagaagc ctgctcccca ggctgcggag cccaacaacc
1381 acacggagta tgccagcatt cagaccagcc cgcagcccgc gtcggaggac accctcacct
1441 atgctgacct ggacatggtc cacctcaacc ggacccccaa gcagccggcc cccaagcctg
1501 agccgtcctt ctcagagtac gccagcgtcc aggtcccgag gaagtgaatg ggaccgtggt
1561 ttgctctagc acccatctct acgcgctttc ttgtcccaca gggagccgcc gtgatgagca
1621 cagccaaccc agttcccgga gggctggggc ggtgcaggct ctgggaccca ggggccaggg
1681 tggctcttct ctccccaccc ctccttggct ctccagcact tcctgggcag ccacggcccc
1741 ctccccccac attgccacat acctggaggc tgacgttgcc aaaccagcca gggaaccaac
1801 ctgggaagtg gccagaactt cctggggtcc aagaactctt gtgcctccgt ccatcaccat
1861 gtgggttttg aagaccctcg actgcctccc cgatgctccg aagcctgatc ttccagggtg
1921 gggaggagaa aatcccacct cccctgacct ccaccacctc caccaccacc accaccacca
1981 ccaccaccac taccaccacc acccaactgg ggctagagtg gggaagattt cccctttaga
2041 tcaaactgcc ccttccatgg aaaagctgga aaaaaactct ggaacccata tccaggcttg
2101 gtgaggttgc tgccaacagt cctggcctcc cccatcccta ggctaaagag ccatgagtcc
2161 tggaggagga gaggacccct cccaaaggac tggagacaaa accctctgct tccttgggtc
2221 cctccaagac tccctggggc ccaactgtgt tgctccaccc ggacccatct ctcccttcta
2281 gacctgagct tgcccctcca gctagcacta agcaacatct cgctgtggac gcctgtaaat
2341 tactgagaaa tgtgaaacgt gcaatcttga aactgaggtg ttagaaaact taaaaaaaaa
2401 aaaaaaaaaa aaaaaaaaac caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2461 aaaaa
//