LOCUS BC033039 5041 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens leucine-rich repeat-containing G protein-coupled
receptor 4, mRNA (cDNA clone MGC:33719 IMAGE:5260923), complete
cds.
ACCESSION BC033039
VERSION BC033039.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5041)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5041)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC033039.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: f Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8923700.
FEATURES Location/Qualifiers
source 1..5041
/db_xref="H-InvDB:HIT000041774"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33719 IMAGE:5260923"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..5041
/gene="LGR4"
/db_xref="GeneID:55366"
/db_xref="MIM:606666"
CDS 474..3257
/gene="LGR4"
/codon_start=1
/product="LGR4 protein"
/protein_id="AAH33039.1"
/db_xref="GeneID:55366"
/db_xref="MIM:606666"
/translation="MPGPLGLLCFLALGLLGSAGPGGAAPPLCAAPCSCDGDRRVDCS
GKGLTAVPEGLSAFTQALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIR
GLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTL
ALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ
AIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHS
LVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL
PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPIT
NLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFW
GCDSYANLNTEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPC
EYLLGSWMIRLTVWFIFLVALFFNLLVILTTFASCTSLPSSKLFIGLISVSNLFMGIY
TGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAK
DIMKNGKSNHLKQFRVAALLAFLGATVAGCFPIFHRGEYSASPLCLPFPTGETPSLGF
TVTLVLLNSLAFLLMAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVA
FFSFAPLITAISISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRRVTKK
SGSVSVSISSQGGCLEQDFYYDCGMYSHLQGNLTVCDCCESFLLTKPVSCKHLIKSHS
CPALAVASCQRPEGYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFP
LVRYAYNLPRVKD"
BASE COUNT 1405 a 1040 c 1107 g 1489 t
ORIGIN
1 agaagggaaa aggacgggaa gagattgagc cgcggctggg agacagcgag ccagagtctg
61 ggtgtttgtg cgagagccac ggcgggggct ggggcgagtg gccggcatgg ctgaaggctg
121 cgctctgcaa ccttgaagag ccgctgcatt gagaggccag ggacagggag accggtgcga
181 tggcagagcg cggcccccgc cgctgcgccg ggccggcccg gctggcctga gccgccggag
241 gagcggggct gcctctgcgc gtccatggag cagcgggaag ggcgaaactc cggagcgccg
301 cgtccctgcg ccgctgcggc ggactgctga aggggccgag cccgcgcgga ccgccgagga
361 agagaccccc gctccagccc gcaggccggc tgcccggggg cggcggggga catcggaggg
421 cagcggagcg agcagcgccg cgggagaggc cggcgcggga ggcggccgca gcaatgccgg
481 gcccgctagg gctgctctgc ttcctcgccc tggggctgct cggctcggcc gggcccggcg
541 gcgcggcgcc gcctctctgc gcggcgccct gcagctgcga cggcgaccgt cgggtggact
601 gctccgggaa ggggctgacg gccgtgcccg aggggctcag cgccttcacc caagcgctac
661 aattggcggg caacgacctt tcttttatcc acccaaaggc cttgtctggg ttgaaagaac
721 tcaaagttct aacgctccag aataatcagt tgaaaacagt acccagtgaa gccattcgag
781 ggctgagtgc tttgcagtct ttgcgtttag atgccaacca tattacctca gtccccgagg
841 acagttttga aggacttgtt cagttacggc atctgtggct ggatgacaac agcttgacgg
901 aggtgcctgt gcaccacctc agcaatctgc ccaccctaca ggcgctgacc ctggctctca
961 acaagatctc aagcatccct gactttgcat ttaccaacct ttcaagcctg gtagttctgc
1021 atcttcataa caataaaatt agaagcctga gtcaacactg ttttgatgga ctagataacc
1081 tggagacctt agacttgaat tataataact tgggggaatt tcctcaggct attaaagccc
1141 ttcctagcct taaagagcta ggatttcata gtaattctat ttctgttatc cctgatggag
1201 catttgatgg taatccactc ttaagaacta tacatttgta tgataatcct ctgtcttttg
1261 tggggaactc agcatttcac aatttatctg atcttcattc cctagtcatt cgtggtgcaa
1321 gcatggtgca gcagttcccc aatcttacag gaactgtcca cctggaaagt ctgactttga
1381 caggtacaaa gataagcagc atacctaata atttgtgtca agaacaaaag atgcttagga
1441 ctttggactt gtcttacaat aatataagag accttccaag ttttaatggt tgccatgctc
1501 tggaagaaat ttctttacag cgtaatcaaa tctaccaaat aaaggaaggc acctttcaag
1561 gcctgatatc tctaaggatt ctagatctga gtagaaacct gatacatgaa attcacagta
1621 gagcttttgc cacacttggg ccaataacta acctagatgt aagtttcaat gaattaactt
1681 cctttcctac ggaaggcctg aatgggctaa atcaactgaa acttgtgggc aacttcaagc
1741 tgaaagaagc cttagcagca aaagactttg ttaacctcag gtctttatca gtaccatatg
1801 cttatcagtg ctgtgcattt tggggttgtg actcttatgc aaatttaaac acagaagata
1861 acagcctcca ggaccacagt gtggcacagg agaaaggtac tgctgatgca gcaaatgtca
1921 caagcactct tgaaaatgaa gaacatagtc aaataattat ccattgtaca ccttcaacag
1981 gtgcttttaa gccctgtgaa tatttactgg gaagctggat gattcgtctt actgtgtggt
2041 tcattttctt ggttgcatta tttttcaacc tgcttgttat tttaacaaca tttgcatctt
2101 gtacatcact gccttcgtcc aaattgttta taggcttgat ttctgtgtct aacttattca
2161 tgggaatcta tactggcatc ctaacttttc ttgatgctgt gtcctggggc agattcgctg
2221 aatttggcat ttggtgggaa actggcagtg gctgcaaagt agctgggttt cttgcagttt
2281 tctcctcaga aagtgccata tttttattaa tgctagcaac tgtcgaaaga agcttatctg
2341 caaaagatat aatgaaaaat gggaagagca atcatctcaa acagttccgg gttgctgccc
2401 ttttggcttt cctaggtgct acagtagcag gctgttttcc cattttccat agaggggaat
2461 attctgcatc acccctttgt ttgccatttc ctacaggtga aacgccatca ttaggattca
2521 ctgtaacgtt agtgctatta aactcactag catttttatt aatggccgtt atctacacta
2581 agctatactg caacttggaa aaagaggacc tctcagaaaa ctcacaatct agcatgatta
2641 agcatgtcgc ttggctaatc ttcaccaatt gcatcttttt ctgccctgtg gcgttttttt
2701 catttgcacc attgatcact gcaatctcta tcagccccga aataatgaag tctgttactc
2761 tgatattttt tccattgcct gcttgcctga atccagtcct gtatgttttc ttcaacccaa
2821 agtttaaaga agactggaag ttactgaagc gacgtgttac caagaaaagt ggatcagttt
2881 cagtttccat cagtagccaa ggtggttgtc tggaacagga tttctactac gactgtggca
2941 tgtactcaca tttgcagggc aacctgactg tttgcgactg ctgcgaatcg tttcttttaa
3001 caaagccagt atcatgcaaa cacttgataa aatcacacag ctgtcctgca ttggcagtgg
3061 cttcttgcca aagacctgag ggctactggt ccgactgtgg cacacagtcg gcccactctg
3121 attatgcaga tgaagaagat tcctttgtct cagacagttc tgaccaggtg caggcctgtg
3181 gacgagcctg cttctaccag agtagaggat tccctttggt gcgctatgct tacaatctac
3241 caagagttaa agactgaact actgagtgtg taaccgtttc ccccgtcaac caaaatcagt
3301 gtttatagag tgaaccctat tctcatcttt catctgggaa gcacttctgt aatcactgcc
3361 tggtgtcact tagaagaagg agaggtggca gtttatttct caaaccagtc attttcaaag
3421 aacaggtgct taaattataa attggtgaaa aatgcaatgt ccaagcaatg tatgatctgt
3481 ttgaaacaaa tatatgactt gaaaaggatc ttaggtgtag tagagcaata taatgttagt
3541 tttttctgat ccataagaag caaatttata cctatttgtg tattaagcac aagataaaga
3601 acagctgtta atatttttta aaaatctatt ttaaaatgtg attttctata actgaagaaa
3661 atatcttgct aattttacct aatgtttcat ccttaatctc aggacaactt actgcagggc
3721 caaaaaaggg actgtcccag ctagaactgt gagagtatac ataggcatta ctttattatg
3781 ttttcacttg ccatccttga cataagagaa ctataaattt tgtttaagca atttataaat
3841 ctaaaacctg aagatgtttt taaaacaata ttaacagctg ttaggttaaa aaaatagctg
3901 gacatttgtt ttcagtcatt atacattgct ttggtccaat cagtaatttt ttcttaagtg
3961 ttttgtgatt acactactag aaaaaaagta aaaggctaat tgctgtgtgg gtttagtcga
4021 tttggctaaa ctactaacta atgtgggggt ttaatagtat ctgagggatt tggtggcttc
4081 atgtaatgtt ctcattaatg aatacttcct aatatcgttg gctctactaa tattttccaa
4141 tttgctggga tgtcacctag caatagtttg gattatatag aaagtaaact gtggtcaata
4201 cttgcattta attagacgaa acggggagta attatgacac gaagtactta tgtttatttc
4261 ttagtgagct ggattatctt gaacctgtgc tattaaatgg aaatttccat acatcttccc
4321 catactattt tttataaaag agcctattca atagctcaga ggttgaactc tggttaaaca
4381 agataatatg ttattaataa agatagaaga agaaagaata aagcttagtc ctgtgtcttt
4441 aaaaattaaa aattttactt gattcccatc tatgggcttt agacctatta ctgggtggag
4501 tcttaaagtt ataattgttc aatatgtttt ttgaacagtg tgctaaatca atagcaaacc
4561 cactgccata ttagttattc tgaatatact aaaaaaatcc agctagattg cagtttaata
4621 attaaactgt acatactgtg catataatga atttttatct tatgtaaatt atttttagaa
4681 cacaagttgg gaaatgtggc ttctgttcat ttcgtttaat taaagctacc tcctaaacta
4741 tagtggctgc cagtagcaga ctgttaaatt gtggtttata tactttttgc attgtaaata
4801 gtctttgttg tacattgtca gtgtaataaa aacagaatct ttgtatatca aaatcatgta
4861 gtttgtataa aatgtgggaa ggatttattt acagtgtgtt gtaattttgt aaggccaact
4921 atttacaagt tttaaaaatt gctatcatgt atatttacac atctgataaa tattaaatca
4981 taacttggta agaaactcct aattaaaagg ttttttccaa aatccaaaaa aaaaaaaaaa
5041 a
//