LOCUS BC032858 2980 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens TTK protein kinase, mRNA (cDNA clone MGC:33286
IMAGE:5270012), complete cds.
ACCESSION BC032858
VERSION BC032858.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2980)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2980)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC032858.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 47 Row: p Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34303964.
FEATURES Location/Qualifiers
source 1..2980
/db_xref="H-InvDB:HIT000051083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33286 IMAGE:5270012"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2980
/gene="TTK"
/gene_synonym="ESK"
/gene_synonym="MPS1L1"
/gene_synonym="PYT"
/db_xref="GeneID:7272"
/db_xref="HGNC:HGNC:12401"
/db_xref="MIM:604092"
CDS 77..2650
/gene="TTK"
/gene_synonym="ESK"
/gene_synonym="MPS1L1"
/gene_synonym="PYT"
/codon_start=1
/product="TTK protein kinase"
/protein_id="AAH32858.1"
/db_xref="GeneID:7272"
/db_xref="HGNC:HGNC:12401"
/db_xref="MIM:604092"
/translation="MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISAD
TTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDK
YGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVK
KSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGS
LGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPV
NLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSH
FKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQKQWQSKRK
SECINQNPAASSNHWQIPELARKVNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSI
CKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQV
LASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLD
SYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWER
KSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDS
QVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQ
ISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPV
NQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGK
K"
BASE COUNT 1066 a 524 c 558 g 832 t
ORIGIN
1 gggggaattc aaacgtgttt gcggaaagga gtttgggttc catcttttca tttccccagc
61 gcagctttct gtagaaatgg aatccgagga tttaagtggc agagaattga caattgattc
121 cataatgaac aaagtgagag acattaaaaa taagtttaaa aatgaagacc ttactgatga
181 actaagcttg aataaaattt ctgctgatac tacagataac tcgggaactg ttaaccaaat
241 tatgatgatg gcaaacaacc cagaggactg gttgagtttg ttgctcaaac tagagaaaaa
301 cagtgttccg ctaagtgatg ctcttttaaa taaattgatt ggtcgttaca gtcaagcaat
361 tgaagcgctt cccccagata aatatggcca aaatgagagt tttgctagaa ttcaagtgag
421 atttgctgaa ttaaaagcta ttcaagagcc agatgatgca cgtgactact ttcaaatggc
481 cagagcaaac tgcaagaaat ttgcttttgt tcatatatct tttgcacaat ttgaactgtc
541 acaaggtaat gtcaaaaaaa gtaaacaact tcttcaaaaa gctgtagaac gtggagcagt
601 accactagaa atgctggaaa ttgccctgcg gaatttaaac ctccaaaaaa agcagctgct
661 ttcagaggag gaaaagaaga atttatcagc atctacggta ttaactgccc aagaatcatt
721 ttccggttca cttgggcatt tacagaatag gaacaacagt tgtgattcca gaggacagac
781 tactaaagcc aggtttttat atggagagaa catgccacca caagatgcag aaataggtta
841 ccggaattca ttgagacaaa ctaacaaaac taaacagtca tgcccatttg gaagagtccc
901 agttaacctt ctaaatagcc cagattgtga tgtgaagaca gatgattcag ttgtaccttg
961 ttttatgaaa agacaaacct ctagatcaga atgccgagat ttggttgtgc ctggatctaa
1021 accaagtgga aatgattcct gtgaattaag aaatttaaag tctgttcaaa atagtcattt
1081 caaggaacct ctggtgtcag atgaaaagag ttctgaactt attattactg attcaataac
1141 cctgaagaat aaaacggaat caagtcttct agctaaatta gaagaaacta aagagtatca
1201 agaaccagag gttccagaga gtaaccagaa acagtggcaa tctaagagaa agtcagagtg
1261 tattaaccag aatcctgctg catcttcaaa tcactggcag attccggagt tagcccgaaa
1321 agttaataca gagcagaaac ataccacttt tgagcaacct gtcttttcag tttcaaaaca
1381 gtcaccacca atatcaacat ctaaatggtt tgacccaaaa tctatttgta agacaccaag
1441 cagcaatacc ttggatgatt acatgagctg ttttagaact ccagttgtaa agaatgactt
1501 tccacctgct tgtcagttgt caacacctta tggccaacct gcctgtttcc agcagcaaca
1561 gcatcaaata cttgccactc cacttcaaaa tttacaggtt ttagcatctt cttcagcaaa
1621 tgaatgcatt tcggttaaag gaagaattta ttccatatta aagcagatag gaagtggagg
1681 ttcaagcaag gtatttcagg tgttaaatga aaagaaacag atatatgcta taaaatatgt
1741 gaacttagaa gaagcagata accaaactct tgatagttac cggaacgaaa tagcttattt
1801 gaataaacta caacaacaca gtgataagat catccgactt tatgattatg aaatcacgga
1861 ccagtacatc tacatggtaa tggagtgtgg aaatattgat cttaatagtt ggcttaaaaa
1921 gaaaaaatcc attgatccat gggaacgcaa gagttactgg aaaaatatgt tagaggcagt
1981 tcacacaatc catcaacatg gcattgttca cagtgatctt aaaccagcta actttctgat
2041 agttgatgga atgctaaagc taattgattt tgggattgca aaccaaatgc aaccagatac
2101 aacaagtgtt gttaaagatt ctcaggttgg cacagttaat tatatgccac cagaagcaat
2161 caaagatatg tcttcctcca gagagaatgg gaaatctaag tcaaagataa gccccaaaag
2221 tgatgtttgg tccttaggat gtattttgta ctatatgact tacgggaaaa caccatttca
2281 gcagataatt aatcagattt ctaaattaca tgccataatt gatcctaatc atgaaattga
2341 atttcccgat attccagaga aagatcttca agatgtgtta aagtgttgtt taaaaaggga
2401 cccaaaacag aggatatcca ttcctgagct cctggctcat ccatatgttc aaattcaaac
2461 tcatccagtt aaccaaatgg ccaagggaac cactgaagaa atgaaatatg ttctgggcca
2521 acttgttggt ctgaattctc ctaactccat tttgaaagct gctaaaactt tatatgaaca
2581 ctatagtggt ggtgaaagtc ataattcttc atcctccaag acttttgaaa aaaaaagggg
2641 aaaaaaatga tttgcagtta ttcgtaatgt cagataccac ctataaaata tattggactg
2701 ttatactctt gaatccctgt ggaaatctac atttgaagac aacatcactc tgaagtgtta
2761 tcagcaaaaa aaattcagta gattatcttt aaaagaaaac tataaaaata gcaaccactt
2821 atggcactgt atatattgta gacttgtttt ctctgtttta tgctcttgtg taatctactt
2881 gacatcattt tactcttgga atagtgggtg gatagcaagt atattctaaa aaactttgta
2941 aataaagttt tgtggctaaa atgacaaaaa aaaaaaaaaa
//