LOCUS BC032783 2787 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens glycoprotein (transmembrane) nmb, mRNA (cDNA clone
MGC:45334 IMAGE:5177095), complete cds.
ACCESSION BC032783
VERSION BC032783.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2787)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2787)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 68 Row: k Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52694750.
FEATURES Location/Qualifiers
source 1..2787
/db_xref="H-InvDB:HIT000041718"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45334 IMAGE:5177095"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2787
/gene="GPNMB"
/gene_synonym="HGFIN"
/gene_synonym="NMB"
/db_xref="GeneID:10457"
/db_xref="HGNC:HGNC:4462"
/db_xref="MIM:604368"
CDS 78..1796
/gene="GPNMB"
/gene_synonym="HGFIN"
/gene_synonym="NMB"
/codon_start=1
/product="glycoprotein (transmembrane) nmb"
/protein_id="AAH32783.1"
/db_xref="GeneID:10457"
/db_xref="HGNC:HGNC:4462"
/db_xref="MIM:604368"
/translation="MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQL
NGWSSDENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIF
PRCQKEDANGNIVYEKNCRNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGK
PFPHHPGWRRWNFIYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGR
AYVPIAQVKDVYVVTDQIPVFVTMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNY
STINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSK
PTPSLATTLKSYDSNTPGPAGDNPLELSRIPDENCQINRYGHFQATITIVEGILEVNI
IQMTDVLMPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPVDVDEMC
LLTVRRTFNGSGTYCVNLTLGDDTSLALTSTLISVPDRDPASPLRMANSALISVGCLA
IFVTVISLLVYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQEKDPLLKNQ
EFKGVS"
BASE COUNT 855 a 605 c 596 g 731 t
ORIGIN
1 acactgttgc tcttggtgga cgggcccaga ggaattcaga gttaaacctt gagtgcctgc
61 gtccgtgaga attcagcatg gaatgtctct actatttcct gggatttctg ctcctggctg
121 caagattgcc acttgatgcc gccaaacgat ttcatgatgt gctgggcaat gaaagacctt
181 ctgcttacat gagggagcac aatcaattaa atggctggtc ttctgatgaa aatgactgga
241 atgaaaaact ctacccagtg tggaagcggg gagacatgag gtggaaaaac tcctggaagg
301 gaggccgtgt gcaggcggtc ctgaccagtg actcaccagc cctcgtgggc tcaaatataa
361 catttgcggt gaacctgata ttccctagat gccaaaagga agatgccaat ggcaacatag
421 tctatgagaa gaactgcaga aatgaggctg gtttatctgc tgatccgtat gtttacaact
481 ggacagcatg gtcagaggac agtgacgggg aaaatggcac cggccaaagc catcataacg
541 tcttccctga tgggaaacct tttcctcacc accccggatg gagaagatgg aatttcatct
601 acgtcttcca cacacttggt cagtatttcc agaaattggg acgatgttca gtgagagttt
661 ctgtgaacac agccaatgtg acacttgggc ctcaactcat ggaagtgact gtctacagaa
721 gacatggacg ggcatatgtt cccatcgcac aagtgaaaga tgtgtacgtg gtaacagatc
781 agattcctgt gtttgtgact atgttccaga agaacgatcg aaattcatcc gacgaaacct
841 tcctcaaaga tctccccatt atgtttgatg tcctgattca tgatcctagc cacttcctca
901 attattctac cattaactac aagtggagct tcggggataa tactggcctg tttgtttcca
961 ccaatcatac tgtgaatcac acgtatgtgc tcaatggaac cttcagcctt aacctcactg
1021 tgaaagctgc agcaccagga ccttgtccgc caccgccacc accacccaga ccttcaaaac
1081 ccaccccttc tttagcaact actctaaaat cttatgattc aaacacccca ggacctgctg
1141 gtgacaaccc cctggagctg agtaggattc ctgatgaaaa ctgccagatt aacagatatg
1201 gccactttca agccaccatc acaattgtag agggaatctt agaggttaac atcatccaga
1261 tgacagacgt cctgatgccg gtgccatggc ctgaaagctc cctaatagac tttgtcgtga
1321 cctgccaagg gagcattccc acggaggtct gtaccatcat ttctgacccc acctgcgaga
1381 tcacccagaa cacagtctgc agccctgtgg atgtggatga gatgtgtctg ctgactgtga
1441 gacgaacctt caatgggtct gggacgtact gtgtgaacct caccctgggg gatgacacaa
1501 gcctggctct cacgagcacc ctgatttctg ttcctgacag agacccagcc tcgcctttaa
1561 ggatggcaaa cagcgccctg atctccgttg gctgcttggc catatttgtc actgtgatct
1621 ccctcttggt gtacaaaaaa cacaaggaat acaacccaat agaaaatagt cctgggaatg
1681 tggtcagaag caaaggcctg agtgtctttc tcaaccgtgc aaaagccgtg ttcttcccgg
1741 gaaaccagga aaaggatccg ctactcaaaa accaagaatt taaaggagtt tcttaaattt
1801 cgaccttgtt tctgaagctc acttttcagt gccattgatg tgagatgtgc tggagtggct
1861 attaaccttt ttttcctaaa gattattgtt aaatagatat tgtggtttgg ggaagttgaa
1921 ttttttatag gttaaatgtc attttagaga tggggagagg gattatactg caggcagctt
1981 cagccatgtt gtgaaactga taaaagcaac ttagcaaggc ttcttttcat tattttttat
2041 gtttcactta taaagtctta ggtaactagt aggatagaaa cactgtgtcc cgagagtaag
2101 gagagaagct actattgatt agagcctaac ccaggttaac tgcaagaaga ggcgggatac
2161 tttcagcttt ccatgtaact gtatgcataa agccaatgta gtccagtttc taagatcatg
2221 ttccaagcta actgaatccc acttcaatac acactcatga actcctgatg gaacaataac
2281 aggcccaagc ctgtggtatg atgtgcacac ttgctagact cagaaaaaat actactctca
2341 taaatgggtg ggagtatttt ggtgacaacc tactttgctt ggctgagtga aggaatgata
2401 ttcatatatt catttattcc atggacattt agttagtgct ttttatatac caggcatgat
2461 gctgagtgac actcttgtgt atatttccaa atttttgtac agtcgctgca catatttgaa
2521 atcatatatt aagactttcc aaagatgagg tccctggttt ttcatggcaa cttgatcagt
2581 aaggatttca cctctgtttg taactaaaac catctactat atgttagaca tgacattctt
2641 tttctctcct tcctgaaaaa taaagtgtgg gaagagacaa aaaaaaaaaa aaaaaaaaaa
2701 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//