LOCUS BC032713 3384 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens toll-like receptor 9, mRNA (cDNA clone MGC:45083
IMAGE:5495717), complete cds.
ACCESSION BC032713
VERSION BC032713.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3384)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3384)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: f Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20302170.
FEATURES Location/Qualifiers
source 1..3384
/db_xref="H-InvDB:HIT000041686"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45083 IMAGE:5495717"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3384
/gene="TLR9"
/gene_synonym="CD289"
/db_xref="GeneID:54106"
/db_xref="HGNC:HGNC:15633"
/db_xref="MIM:605474"
CDS 97..3195
/gene="TLR9"
/gene_synonym="CD289"
/codon_start=1
/product="toll-like receptor 9"
/protein_id="AAH32713.1"
/db_xref="GeneID:54106"
/db_xref="HGNC:HGNC:15633"
/db_xref="MIM:605474"
/translation="MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVN
CNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVG
LSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDS
ASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNL
PSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLH
PDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLT
QLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPM
LQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQP
GDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCI
SQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGH
NFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFF
QGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVL
DLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTV
DHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQG
LSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPW
RGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWL
PGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILS
PDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPT
AE"
BASE COUNT 639 a 1193 c 884 g 668 t
ORIGIN
1 ccacgcgtcc ggggacctcg agtgtgaagc atccttccct gtagctgctg tccagtctgc
61 ccgccagacc ctctggagaa gcccctgccc cccagcatgg gtttctgccg cagcgccctg
121 cacccgctgt ctctcctggt gcaggccatc atgctggcca tgaccctggc cctgggtacc
181 ttgcctgcct tcctaccctg tgagctccag ccccacggcc tggtgaactg caactggctg
241 ttcctgaagt ctgtgcccca cttctccatg gcagcacccc gtggcaatgt caccagcctt
301 tccttgtcct ccaaccgcat ccaccacctc catgattctg actttgccca cctgcccagc
361 ctgcggcatc tcaacctcaa gtggaactgc ccgccggttg gcctcagccc catgcacttc
421 ccctgccaca tgaccatcga gcccagcacc ttcttggctg tgcccaccct ggaagagcta
481 aacctgagct acaacaacat catgactgtg cctgcgctgc ccaaatccct catatccctg
541 tccctcagcc ataccaacat cctgatgcta gactctgcca gcctcgccgg cctgcatgcc
601 ctgcgcttcc tattcatgga cggcaactgt tattacaaga acccctgcag gcaggcactg
661 gaggtggccc cgggtgccct ccttggcctg ggcaacctca cccacctgtc actcaagtac
721 aacaacctca ctgtggtgcc ccgcaacctg ccttccagcc tggagtatct gctgttgtcc
781 tacaaccgca tcgtcaaact ggcgcctgag gacctggcca atctgaccgc cctgcgtgtg
841 ctcgatgtgg gcggaaattg ccgccgctgc gaccacgctc ccaacccctg catggagtgc
901 cctcgtcact tcccccagct acatcccgat accttcagcc acctgagccg tcttgaaggc
961 ctggtgttga aggacagttc tctctcctgg ctgaatgcca gttggttccg tgggctggga
1021 aacctccgag tgctggacct gagtgagaac ttcctctaca aatgcatcac taaaaccaag
1081 gccttccagg gcctaacaca gctgcgcaag cttaacctgt ccttcaatta ccaaaagagg
1141 gtgtcctttg cccacctgtc tctggcccct tccttcggga gcctggtcgc cctgaaggag
1201 ctggacatgc acggcatctt cttccgctca ctcgatgaga ccacgctccg gccactggcc
1261 cgcctgccca tgctccagac tctgcgtctg cagatgaact tcatcaacca ggcccagctc
1321 ggcatcttca gggccttccc tggcctgcgc tacgtggacc tgtcggacaa ccgcatcagc
1381 ggagcttcgg agctgacagc caccatgggg gaggcagatg gaggggagaa ggtctggctg
1441 cagcctgggg accttgctcc ggccccagtg gacactccca gctctgaaga cttcaggccc
1501 aactgcagca ccctcaactt caccttggat ctgtcacgga acaacctggt gaccgtgcag
1561 ccggagatgt ttgcccagct ctcgcacctg cagtgcctgc gcctgagcca caactgcatc
1621 tcgcaggcag tcaatggctc ccagttcctg ccgctgaccg gtctgcaggt gctagacctg
1681 tcccacaata agctggacct ctaccacgag cactcattca cggagctacc acgactggag
1741 gccctggacc tcagctacaa cagccagccc tttggcatgc agggcgtggg ccacaacttc
1801 agcttcgtgg ctcacctgcg caccctgcgc cacctcagcc tggcccacaa caacatccac
1861 agccaagtgt cccagcagct ctgcagtacg tcgctgcggg ccctggactt cagcggcaat
1921 gcactgggcc atatgtgggc cgagggagac ctctatctgc acttcttcca aggcctgagc
1981 ggtttgatct ggctggactt gtcccagaac cgcctgcaca ccctcctgcc ccaaaccctg
2041 cgcaacctcc ccaagagcct acaggtgctg cgtctccgtg acaattacct ggccttcttt
2101 aagtggtgga gcctccactt cctgcccaaa ctggaagtcc tcgacctggc aggaaaccag
2161 ctgaaggccc tgaccaatgg cagcctgcct gctggcaccc ggctccggag gctggatgtc
2221 agctgcaaca gcatcagctt cgtggccccc ggcttctttt ccaaggccaa ggagctgcga
2281 gagctcaacc ttagcgccaa cgccctcaag acagtggacc actcctggtt tgggcccctg
2341 gcgagtgccc tgcaaatact agatgtaagc gccaaccctc tgcactgcgc ctgtggggcg
2401 gcctttatgg acttcctgct ggaggtgcag gctgccgtgc ccggtctgcc cagccgggtg
2461 aagtgtggca gtccgggcca gctccagggc ctcagcatct ttgcacagga cctgcgcctc
2521 tgcctggatg aggccctctc ctgggactgt ttcgccctct cgctgctggc tgtggctctg
2581 ggcctgggtg tgcccatgct gcatcacctc tgtggctggg acctctggta ctgcttccac
2641 ctgtgcctgg cctggcttcc ctggcggggg cggcaaagtg ggcgagatga ggatgccctg
2701 ccctacgatg ccttcgtggt cttcgacaaa acgcagagcg cagtggcaga ctgggtgtac
2761 aacgagcttc gggggcagct ggaggagtgc cgtgggcgct gggcactccg cctgtgcctg
2821 gaggaacgcg actggctgcc tggcaaaacc ctctttgaga acctgtgggc ctcggtctat
2881 ggcagccgca agacgctgtt tgtgctggcc cacacggacc gggtcagtgg tctcttgcgc
2941 gccagcttcc tgctggccca gcagcgcctg ctggaggacc gcaaggacgt cgtggtgctg
3001 gtgatcctga gccctgacgg ccgccgctcc cgctacgtgc ggctgcgcca gcgcctctgc
3061 cgccagagtg tcctcctctg gccccaccag cccagtggtc agcgcagctt ctgggcccag
3121 ctgggcatgg ccctgaccag ggacaaccac cacttctata accggaactt ctgccaggga
3181 cccacggccg aatagccgtg agccggaatc ctgcacggtg ccacctccac actcacctca
3241 cctctgcctg cctggtctga ccctcccctg ctcgcctccc tcaccccaca cctgacacag
3301 agcaggcact caataaatgc taccgaaggc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aaaaaaaaaa aaaa
//