LOCUS BC032579 2220 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens orthodenticle homeobox 2, mRNA (cDNA clone MGC:45000
IMAGE:5493541), complete cds.
ACCESSION BC032579
VERSION BC032579.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2220)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2220)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: e Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27436931.
FEATURES Location/Qualifiers
source 1..2220
/db_xref="H-InvDB:HIT000041614"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45000 IMAGE:5493541"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2220
/gene="OTX2"
/gene_synonym="MCOPS5"
/db_xref="GeneID:5015"
/db_xref="HGNC:HGNC:8522"
/db_xref="MIM:600037"
CDS 286..1179
/gene="OTX2"
/gene_synonym="MCOPS5"
/codon_start=1
/product="orthodenticle homeobox 2"
/protein_id="AAH32579.1"
/db_xref="GeneID:5015"
/db_xref="HGNC:HGNC:8522"
/db_xref="MIM:600037"
/translation="MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPR
KQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR
QQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIW
SPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHH
QLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKL
NFNADCLDYKDQTSSWKFQVL"
BASE COUNT 632 a 524 c 487 g 577 t
ORIGIN
1 ccacgcgtcc ggagagcggg accggcctca gctccaacac agcctccact gtgattaaaa
61 ataaaaattg ctagagcagc cctcactcgc cacatctact ttgatagctg gctatttgga
121 atttaaagga tatttgactt tttctaacct cccatgaggc tgtaagttcc actgctccaa
181 acccacccac caaggactct gaacctgtcc accccgggcg catcaagatc ttccagctgg
241 gtacccccga tttgggccga ctttgcacct ccaaacaacc ttagcatgat gtcttatctt
301 aagcaaccgc cttacgcagt caatgggctg agtctgacca cttcgggtat ggacttgctg
361 cacccctccg tgggctaccc ggggccctgg gcttcttgtc ccgcagccac cccccggaaa
421 cagcgccggg agaggacgac gttcactcgg gcgcagctag atgtgctgga agcactgttt
481 gccaagaccc ggtacccaga catcttcatg cgagaggagg tggcactgaa aatcaacttg
541 cccgagtcga gggtgcaggt atggtttaag aatcgaagag ctaagtgccg ccaacaacag
601 caacaacagc agaatggagg tcaaaacaaa gtgagacctg ccaaaaagaa gacatctcca
661 gctcgggaag tgagttcaga gagtggaaca agtggccaat tcactccccc ctctagcacc
721 tcagtcccga ccattgccag cagcagtgct cctgtgtcta tctggagccc agcttccatc
781 tccccactgt cagatccctt gtccacctcc tcttcctgca tgcagaggtc ctatcccatg
841 acctatactc aggcttcagg ttatagtcaa ggatatgctg gctcaacttc ctactttggg
901 ggcatggact gtggatcata tttgacccct atgcatcacc agcttcccgg accaggggcc
961 acactcagtc ccatgggtac caatgcagtc accagccatc tcaatcagtc cccagcttct
1021 ctttccaccc agggatatgg agcttcaagc ttgggtttta actcaaccac tgattgcttg
1081 gattataagg accaaactgc ctcctggaag cttaacttca atgctgactg cttggattat
1141 aaagatcaga catcctcgtg gaaattccag gttttgtgaa gacctgtaga acctcttttt
1201 gtgggtgatt tttaaatata ctgggctgga cattccagtt ttagccaggc attggttaaa
1261 agagttagat gggatgatgc tcagactcat ctgatcaaag ttccgagagg catagaagga
1321 aaaacgaagg gccttagagg ggcctacaaa ccagcaacat gaaatggaca aaccaatctg
1381 cttaagatcc tgtcatagtt ttagatcatt ggttatcctg atttgcaaag tgatcaaaag
1441 cattctagcc atgtgcaacc aaacaccacc aaaaataaaa tcaaacaaaa ctaagttgtg
1501 aaggaaggga gggaaggtca tagccttctt aagcagaggt gttccattgt tttagccaat
1561 ccttggttga atcttaggaa tgaacagtgt ctcaagctca ttcacgtttc atgaccaact
1621 ggtagttggc actgaaaaaa cttttcaggg ctgtgtgaat tgtgtgactg attgtcctag
1681 atgcactact ttatttaaaa aataatgttc ataaggagtc aatatgtagt ttaagagaca
1741 atcagtgtgt gtcttataaa tggtacatct gtggttttta atctgtgcta gacttcaaaa
1801 ctgtgatctc ctgttattgt atgcaacctt gaactccacc tctgcagggg ttcttctgtg
1861 attaaatagg ttataattat aagcaaaatt cagagcaact gagtactgat ctaaaaagat
1921 tacctttggc tggaggtgag ctgcactgaa actttacgac aaaatgtctc tggacaaaga
1981 gagtcagaga agagaagcaa aaggacacta attcatctgt aatttactgt tggtaagcct
2041 agcagtaaag agacattggt caattgctct gaccctgatg aattattaaa ctgagatcat
2101 tgtcgtttat gcttgcagat gttaaatgga aaagttatat atgcataaac cttttcttcc
2161 tggatttggc agatatgtat aattatatta aaatggttct agcacaaaaa aaaaaaaaaa
//