LOCUS BC032413 2251 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens B lymphoid tyrosine kinase, mRNA (cDNA clone MGC:40359
IMAGE:5216030), complete cds.
ACCESSION BC032413
VERSION BC032413.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2251)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2251)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: l Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33469981.
FEATURES Location/Qualifiers
source 1..2251
/db_xref="H-InvDB:HIT000041531_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40359 IMAGE:5216030"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2251
/gene="BLK"
/gene_synonym="MGC10442"
/db_xref="GeneID:640"
/db_xref="HGNC:HGNC:1057"
/db_xref="MIM:191305"
CDS 191..1708
/gene="BLK"
/gene_synonym="MGC10442"
/codon_start=1
/product="B lymphoid tyrosine kinase"
/protein_id="AAH32413.1"
/db_xref="GeneID:640"
/db_xref="HGNC:HGNC:1057"
/db_xref="MIM:191305"
/translation="MGLVSSKKPDKEKPIKEKDKGQWSPLKVSAQDKDAPPLPPLVVF
NHLTPPPPDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLKGTGDWWLARSLVT
GREGYVPSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAF
SLSVKDVTTQGELIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTL
PCVRPAPQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTM
SPEAFLGEANVMKALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSL
PRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQ
EGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER
GYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTATERQYELQP"
BASE COUNT 527 a 652 c 660 g 412 t
ORIGIN
1 cacctctgtc tgctgccggc agaaagccac aagccatgaa aactgattga gatgagaaga
61 attcatctgg gactggcttt tgctttagga tggtgttgga agttgctcgt tgtcgctagg
121 agcctgctcc actgtaaggg tgtcgggatc tgaagagcta tggtgaaaca ccactgaagc
181 attgccaagg atggggctgg taagtagcaa aaagccggac aaggaaaagc cgatcaaaga
241 gaaggacaag ggccaatgga gccccctgaa ggtcagcgcc caagacaagg acgccccgcc
301 actgccgccc ctggttgtct tcaaccacct tactcctcca ccgcccgatg aacacctgga
361 tgaagacaag catttcgtgg tggctctgta tgactacacc gctatgaatg atcgggacct
421 gcagatgctg aagggggaga agctacaggt cctgaaggga actggagact ggtggctggc
481 caggtcactc gtcacaggaa gagaaggcta tgtgcccagt aactttgtgg cccgagtgga
541 gagcctggaa atggaaaggt ggttctttag atcacagggt cggaaggagg ctgagaggca
601 gcttcttgct ccaatcaaca aggccggctc ctttcttatc agagagagtg aaaccaacaa
661 aggtgccttc tccctgtctg tgaaggatgt caccacccag ggggagctga tcaagcacta
721 taagatccgc tgcctggatg aagggggcta ctacatctcc ccccggatca ccttcccctc
781 gctccaggcc ctggtgcagc actattctaa gaagggggat ggtctatgcc agaggctgac
841 cctgccctgt gtgcgcccgg ccccgcagaa tccctgggcc caggatgaat gggagatccc
901 ccggcagtct ctcaggctgg tcaggaaact cgggtctgga caattcggcg aagtctggat
961 gggttactac aaaaacaaca tgaaggtggc cattaagacg ctgaaggagg gaaccatgtc
1021 tccagaagcc ttcctgggtg aggccaacgt gatgaaggct ctgcagcacg agcggctggt
1081 ccgactctac gcagtggtca ccaaggagcc catctacatt gtcaccgagt acatggccag
1141 aggatgcctg ctggatttcc tgaagacaga tgaagggagc agattgtcac tcccaaggct
1201 gattgacatg tcggcgcaga ttgctgaagg gatggcatac attgagcgca tgaattccat
1261 ccaccgcgac ctgcgggcgg ccaacatcct ggtgtctgag gccttgtgct gcaaaattgc
1321 tgattttggc ttggctcgaa tcatcgacag tgaatacacg gcccaagagg gggccaagtt
1381 ccccatcaag tggacagccc cggaagccat ccacttcggg gtcttcacca tcaaagcaga
1441 cgtgtggtcg tttggagtcc tcctgatgga agttgtcact tatgggcggg tgccataccc
1501 agggatgagc aaccccgagg tcatccgcaa cctggagcgc ggctaccgca tgccgcgccc
1561 cgacacctgc ccgcccgagc tgtaccgcgg cgtcatcgcc gagtgctggc gcagccggcc
1621 cgaggagcgg cccaccttcg agttcctgca gtcggtgctg gaggacttct acacggccac
1681 cgagcggcag tacgagctgc agccctagcc ggccgcgccc gcctgcgccc cgtgcccacc
1741 tctgcgcgga cgaccccgac ttccgtgcca tcccagacgg gccgcgaagg cggggtgtcg
1801 cctgtgccct tttctcagac ccggaatcca gtgggcagag gcagcttcgc agggggtccc
1861 cggacggact ccttcaccga ctgcaccccc gggcgagtta cgcggcctct ctgtgccgct
1921 tcatttgtag agggctgtaa cagtgacctc gcacggtcat ccggagtact aagccccagt
1981 aaggtgttca ggactggtaa gcgactgtca tcaagtaagg cccccgtgct gggcaccccc
2041 cgtgctggcc gcgtccccgc ctctgcgccc tgcgtggacc ccgccctgcc ccgctacaga
2101 agccagactg ggtcccgcgg acgccagcag gggcaacccc agcctaggct gcgctccagc
2161 actgcggggc ttttctgcaa taaagtcacg agcgttcgaa aaaaaaaaaa aaaaaaaaaa
2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//