LOCUS BC032322 1786 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 51, subfamily A, polypeptide
1, mRNA (cDNA clone MGC:40249 IMAGE:5242474), complete cds.
ACCESSION BC032322
VERSION BC032322.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1786)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1786)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: o Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13929427.
FEATURES Location/Qualifiers
source 1..1786
/db_xref="H-InvDB:HIT000041488"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40249 IMAGE:5242474"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1786
/gene="CYP51A1"
/gene_synonym="CP51"
/gene_synonym="CYPL1"
/gene_synonym="LDM"
/gene_synonym="P450-14DM"
/gene_synonym="P450L1"
/db_xref="GeneID:1595"
/db_xref="HGNC:HGNC:2649"
/db_xref="MIM:601637"
CDS 123..1652
/gene="CYP51A1"
/gene_synonym="CP51"
/gene_synonym="CYPL1"
/gene_synonym="LDM"
/gene_synonym="P450-14DM"
/gene_synonym="P450L1"
/codon_start=1
/product="cytochrome P450, family 51, subfamily A,
polypeptide 1"
/protein_id="AAH32322.1"
/db_xref="GeneID:1595"
/db_xref="HGNC:HGNC:2649"
/db_xref="MIM:601637"
/translation="MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTL
SLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVF
SFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLE
QKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHG
KEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQK
RRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLA
RDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMART
PQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGA
GRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRS
K"
BASE COUNT 543 a 363 c 421 g 459 t
ORIGIN
1 gctgggttta gtaggagacc tggggcaagg ccccctgtgg acgaccatct gccagcttct
61 ctcgttccgt cgattgggag gagcggtggc gacctcggcc ttcagtgttt ccgacggagt
121 gaatggcggc ggcggctggg atgctgctgc tgggcttgct gcaggcgggt gggtcggtgc
181 tgggccaggc gatggagaag gtgacaggcg gcaacctctt gtccatgctg ctgatcgcct
241 gcgccttcac cctcagcctg gtctacctga tccgtctggc cgccggccac ctggtccagc
301 tgcccgcagg ggtgaaaagt cctccataca ttttctcccc aattccattc cttgggcatg
361 ccatagcatt tgggaaaagt ccaattgaat ttctagaaaa tgcatatgag aagtatggac
421 ctgtatttag ttttaccatg gtaggcaaga catttactta ccttctgggg agtgatgctg
481 ctgcactgct ttttaatagt aaaaatgaag acctgaatgc agaagatgtc tacagtcgcc
541 tgacaacacc tgtgtttggg aagggagttg catacgatgt gcctaatcca gttttcttgg
601 agcagaagaa aatgttaaaa agtggcctta acatagccca ctttaaacag catgtttcta
661 taattgaaaa agaaacaaag gaatactttg agagttgggg agaaagtgga gaaaaaaatg
721 tgtttgaagc tctttctgag ctcataattt taacagctag ccattgtttg catggaaagg
781 aaatcagaag tcaactcaat gaaaaggtag cacagctgta tgcagatttg gatggaggtt
841 tcagccatgc agcctggctc ttaccaggtt ggctgccttt gcctagtttc agacgcaggg
901 acagagctca tcgggaaatc aaggatattt tctataaggc aatccagaaa cgcagacagt
961 ctcaagaaaa aattgatgac attctccaaa ctttactaga tgctacatac aaggatgggc
1021 gtcctttgac tgatgatgaa gtagcaggga tgcttattgg attactcttg gcagggcagc
1081 atacatcctc aactactagt gcttggatgg gcttcttttt ggccagagac aaaacacttc
1141 aaaaaaaatg ttatttagaa cagaaaacag tctgtggaga gaatctgcct cctttaactt
1201 atgaccagct caaggatcta aatttacttg atcgctgtat aaaagaaaca ttaagactta
1261 gacctcctgt aatgatcatg atgagaatgg ccagaactcc tcagactgtg gcagggtata
1321 ccattcctcc aggacatcag gtgtgtgttt ctcccactgt caatcaaaga cttaaagact
1381 catgggtaga acgcctggac tttaatcctg atcgctactt acaggataac ccagcatcag
1441 gggaaaagtt tgcctatgtg ccatttggag ctgggcgtca tcgttgtatt ggggaaaatt
1501 ttgcctatgt tcaaattaag acaatttggt ccactatgct tcgtttatat gaatttgatc
1561 tcattgatgg atactttccc actgtgaatt atacaactat gattcacacc cctgaaaacc
1621 cagttatccg ttacaaacga agatcaaaat gaaaaaggtt gcaaggaacg aatatatgtg
1681 attatcactg taagccacaa aggcattcga agagaatgaa gtgtacaaaa caaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//