LOCUS BC031797 3069 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens SRY (sex determining region Y)-box 8, mRNA (cDNA clone
MGC:24837 IMAGE:4937883), complete cds.
ACCESSION BC031797
VERSION BC031797.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3069)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3069)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: o Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 30179902.
FEATURES Location/Qualifiers
source 1..3069
/db_xref="H-InvDB:HIT000041372"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24837 IMAGE:4937883"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3069
/gene="SOX8"
/gene_synonym="MGC24837"
/db_xref="GeneID:30812"
/db_xref="HGNC:HGNC:11203"
/db_xref="MIM:605923"
CDS 116..1456
/gene="SOX8"
/gene_synonym="MGC24837"
/codon_start=1
/product="SRY (sex determining region Y)-box 8"
/protein_id="AAH31797.1"
/db_xref="GeneID:30812"
/db_xref="HGNC:HGNC:11203"
/db_xref="MIM:605923"
/translation="MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGR
AGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHV
KRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV
QHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHT
GQTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGT
MDAFDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGPP
RPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYY
GAYPGYAPGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP"
BASE COUNT 574 a 997 c 948 g 550 t
ORIGIN
1 ggcgagggtc ggggccaccg cgcggcgacc tcgggtcccg gagcgaccgc agggcagccc
61 cgggcgccgg ccccggtgcg cgtctcctgt gcgcgcccct ccgcgcgcgg ccccgatgct
121 ggacatgagc gaggcccgct cccagccgcc ctgcagcccg tccggcaccg ccagctccat
181 gtcgcacgtg gaggactcgg actcggacgc gccgccgtct cccgccggct ccgagggcct
241 gggccgcgcg ggggtcgcgg tggggggcgc ccggggcgac ccggcggagg cggcggacga
301 gcgcttcccg gcctgcatcc gcgacgccgt gtcgcaggtg ctcaagggct acgactggag
361 tctggtgccc atgccggtgc gcggcggcgg cggcggcgcg ctcaaagcca agccgcatgt
421 gaagcggccc atgaacgcat tcatggtgtg ggcgcaggcg gcgcgccgca agctggccga
481 ccagtacccg cacctgcaca acgccgagct cagcaagacg ctgggcaagc tgtggcgctt
541 gctgagcgag agcgagaagc ggcccttcgt ggaggaggca gagcgccttc gcgtgcagca
601 caagaaggac caccccgact acaagtacca gccacggcgc aggaagagcg ccaaagccgg
661 ccacagcgac tccgactcgg gcgcggagct gggaccccac cctggcggcg gtgccgtgta
721 caaggctgaa gcagggcttg gagatgggca ccaccatggc gaccacacag ggcagaccca
781 cgggccgccc accccgccca ccacccccaa gacggagctg cagcaggcgg gcgccaagcc
841 ggagctgaag ctggagggac gccggccggt ggacagcggg cgccagaaca tcgacttcag
901 caacgtggac atctcggagc tcagcagcga ggtcatgggc accatggacg ccttcgacgt
961 ccacgagttc gaccagtacc tgcccctggg cggccccgcc ccacccgagc cgggccaggc
1021 ctacgggggc gcctacttcc acgccggggc gtcccccgtg tgggcccaca agagtgcccc
1081 gtcggcctcc gcgtcgccca ccgagacggg tcccccacgg ccgcacatca agacggagca
1141 gccgagcccc ggccactacg gcgaccagcc ccgaggctcg cccgactacg gttcctgcag
1201 cggccagtcc agcgccaccc cggccgcccc cgccggcccc ttcgccggct cacagggcga
1261 ctatggcgac ctgcaggcct ccagctacta tggtgcctac cctggctacg cacccggcct
1321 ctaccagtac ccctgcttcc actcgccgcg ccggccctac gcctcacccc tgctcaacgg
1381 cctggccctg ccgcccgccc acagccccac cagtcactgg gaccagccgg tgtacaccac
1441 cctgaccagg ccctgagggc ccagccgcgg ggagggactc gcaggcgtca gggggcagcc
1501 ttgtcccggc ccagtgtgtg tgaccggggc gggaggggcc ccagtggctg agctccaagt
1561 gcctgctgaa gtctgcaggg aaacacgctt gctgcccgtg gccctcggcc tccagatggc
1621 cacacctctg ccgacgacgg accagctccc tctcccttct atctttcttt ttgaggtggt
1681 gggattattc cacaaagaag ggctgccgtt tggtccctct tctgtgagga ctggcggcac
1741 cagcaccttc gctttgcatc tcggtagagg agaaacggca gcacagccca aggaccaaag
1801 gagggggtgg caggggcctt gcagggcgct gtgaggtcca ggccggtctt ggcgccgaga
1861 gcccctgcac tcaaggccac attccctcga caacggctgc acgggctgtc cgggatccgg
1921 ggtgtctgtc cgcagactgg gatgagtcta ctcgagcatc tccgggacct gcctgtcaga
1981 tctgaggtgt ctccttgctg gcagagtgcg ctcacgcgag ggctggctgt gatgaacaca
2041 tctctctttt atttttatgt ttttgataat ttttattttt gaagcttaaa tgtgtttctt
2101 ctgaaagctg ttaaagatgt atttatgttc tgtgttattt tatctttaat taatgaggta
2161 attcgggcaa agagtagaat ttaagacaaa acggaagctg ggaagcttcc cttgagggca
2221 ggcaggaggt ggagttgcag ctgttggccg gcatcacgtt gctcgttgct cggcttatgg
2281 gaggccgccc tggagggccc ggaggtccca aggtccctgg gaggactggg cccctcatgc
2341 ctcgagcttg gcaaccgaaa acccgaggga ggagaaggga cctgccttgt gacatctctg
2401 atcaggttgg ggtgccccag cacccagtac tagtttgggg tttgggaagc aggactccgt
2461 ccctgtcccc gactgtgcca cgtggtagga cacataggac acaggaattc ctgggtcctt
2521 gcccatgact gtgccatgtg gtaggacaca ggacacagga attcctggaa agtggtggct
2581 tcagaagtga tcttggctcg caggcaccag tgccacctac caagctgtga aactaaacct
2641 tctccactaa acgtcgttag ggcctcagtt ctagacgagt catacctgat tcacctgcac
2701 tgcttccccc gtgtgctgag catagagcat acaatagcgc ctacttcacg gaaacttgtg
2761 cctttaaact ttgtaaactt aaacacagcc gagaagttgc ttctttgtac tttttctact
2821 tttcctactt ttttgtagaa aaaaaagata atgcctctgc ttctatttct ctgggggtgg
2881 gggtgggggc cgggagccgt cgcagacccg tttcatgcag cgtctccctc ggcaccgcgt
2941 tcggaggacg caccctcact cccctgctgc cttcactcct ttctgaccaa gcaacgctaa
3001 cttttgtaca gatcgatttg ataaaattaa acaaagtgct ttttatggaa aaaaaaaaaa
3061 aaaaaaaaa
//