LOCUS BC031590 2044 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytokine inducible SH2-containing protein, mRNA (cDNA
clone MGC:34375 IMAGE:5182644), complete cds.
ACCESSION BC031590
VERSION BC031590.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2044)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2044)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 50 Row: d Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21614506.
FEATURES Location/Qualifiers
source 1..2044
/db_xref="H-InvDB:HIT000041326"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34375 IMAGE:5182644"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2044
/gene="CISH"
/gene_synonym="CIS"
/gene_synonym="CIS-1"
/gene_synonym="G18"
/gene_synonym="SOCS"
/db_xref="GeneID:1154"
/db_xref="HGNC:HGNC:1984"
/db_xref="MIM:602441"
CDS 114..890
/gene="CISH"
/gene_synonym="CIS"
/gene_synonym="CIS-1"
/gene_synonym="G18"
/gene_synonym="SOCS"
/codon_start=1
/product="cytokine inducible SH2-containing protein"
/protein_id="AAH31590.1"
/db_xref="GeneID:1154"
/db_xref="HGNC:HGNC:1984"
/db_xref="MIM:602441"
/translation="MVLCVQGPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAGAFLE
EVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEG
TFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLV
QHYVASCTADTRSDSPDPAPTPALPMPKEDAPSDPALPAPPPATAVHLKLVQPFVRRS
SARSLQHLCRLVINRLVADVDCLPLPRRMADYLRQYPFQL"
BASE COUNT 432 a 639 c 538 g 435 t
ORIGIN
1 tgcgcccgcg cgccccggga gcctacccag cacgcgctcc gcgcccactg gttccctcca
61 gccgccgccg tccagccgag tccccactcc ggagtcgccg ctgccgcggg gacatggtcc
121 tctgcgttca gggacctcgt cctttgctgg ctgtggagcg gactgggcag cggcccctgt
181 gggccccgtc cctggaactg cccaagccag tcatgcagcc cttgcctgct ggggccttcc
241 tcgaggaggt ggcagagggt accccagccc agacagagag tgagccaaag gtgctggacc
301 cagaggagga tctgctgtgc atagccaaga ccttctccta ccttcgggaa tctggctggt
361 attggggttc cattacggcc agcgaggccc gacaacacct gcagaagatg ccagaaggca
421 cgttcttagt acgtgacagc acgcacccca gctacctgtt cacgctgtca gtgaaaacca
481 ctcgtggccc caccaatgta cgcattgagt atgctgactc cagcttccgt ctggactcca
541 actgcttgtc caggccacgc atcctggcct ttccggatgt ggtcagcctt gtgcagcact
601 atgtggcctc ctgcactgct gatacccgaa gcgacagccc cgatcctgct cccaccccgg
661 ccctgcctat gcctaaggag gatgcgccta gtgacccagc actgcctgct cctccaccag
721 ccactgctgt acacctaaaa ctggtgcagc cctttgtacg cagaagcagc gcccgcagcc
781 tgcaacacct gtgccgcctt gtcatcaacc gtctggtggc cgacgtggac tgcctgccac
841 tgccccggcg catggccgac tacctccgac agtacccctt ccagctctga ctgtacgggg
901 caatctgccc accctcaccc agtcgcaccc tggaggggac atcagcccca gctggacttg
961 ggcccccact gtccctcctc caggcatcct ggtgcctgca tacctctggc agctggccca
1021 ggaagagcca gcaagagcaa ggcatgggag aggggaggtg tcacacaact tggaggtaaa
1081 tgcccccagg ccgcatgtgg cttcattata ctgagccatg tgtcagagga tggggagaca
1141 ggcaggacct tgtctcacct gtgggctggg cccagacctc cactcgcttg cctgccctgg
1201 ccacctgaac tgtatgggca ctctcagccc tggtttttca atccccaggg tcgggtagga
1261 cccctactgg cagccagcct ctgtttctgg gaggatgaca tgcagaggaa ctgagatcga
1321 cagtgactag tgaccccttg ttgaggggta agccaggcta ggggactgca caattataca
1381 ctatttattt atttattctc cttggggttg gtgtcagggg cgagccaacc ccacctctat
1441 gccctgagcc ctggtagtcc agagacccca actctgccct ggcttctctg gttcttccct
1501 gtggaaagcc catcctgaga catcttgctg gaaccaaggc aatcctggat gtcctggtac
1561 tgacccaccc gtctctgaat gtgtccactc tcttctgccc ccagccatat ttggggagga
1621 tggacaacta caataggtaa gaaaatgcag ccggagcctc agtccccagc agagcctgtg
1681 tctcaccccc tcacaggaca gagctgtatc tgcatagagc tggtctcact gtggcgcagg
1741 ccccgggggg agtgcctgtg ctgtcaggaa gagggggtgc tggtttgagg gccgccactg
1801 cagttctgct aggtctgctt cctgcccagg aaggtgcctg cacatgagag gagagaaata
1861 cacgtctgat aagacttcat gaaataataa ttatagcaaa gaacagtttg gtggtctttt
1921 ctcttccact gatttttctg taatgacatt atacctttat tacctcttta ttttattacc
1981 tctataataa aatgatacct ttcatgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2041 aaaa
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