LOCUS BC031562 1213 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 7, member A3 (aflatoxin
aldehyde reductase), mRNA (cDNA clone MGC:34393 IMAGE:5184829),
complete cds.
ACCESSION BC031562
VERSION BC031562.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1213)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1213)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 50 Row: e Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41152111.
FEATURES Location/Qualifiers
source 1..1213
/db_xref="H-InvDB:HIT000041312"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34393 IMAGE:5184829"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1213
/gene="AKR7A3"
/gene_synonym="AFAR2"
/db_xref="GeneID:22977"
/db_xref="HGNC:HGNC:390"
/db_xref="MIM:608477"
CDS 20..1015
/gene="AKR7A3"
/gene_synonym="AFAR2"
/codon_start=1
/product="aldo-keto reductase family 7, member A3
(aflatoxin aldehyde reductase)"
/protein_id="AAH31562.1"
/db_xref="GeneID:22977"
/db_xref="HGNC:HGNC:390"
/db_xref="MIM:608477"
/translation="MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEID
TAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRL
QCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFMELGLSNYAAWEVAEICTLCKSN
GWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQ
PVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQ
LQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR"
BASE COUNT 293 a 352 c 341 g 227 t
ORIGIN
1 gtctcccgtt gccgccgtca tgtcccggca gctgtcgcgg gcccggccag ccacggtgct
61 gggcgccatg gagatggggc gccgcatgga cgcgcccacc agcgccgcag tcacgcgcgc
121 cttcctggag cgcggccaca ccgagataga cacggccttc gtgtacagcg agggccagtc
181 cgagaccatc cttggcggcc tggggctccg gctgggcggc agcgactgca gagtgaaaat
241 tgataccaag gccattccac tgtttgggaa ctccctgaag cctgacagtc tccggttcca
301 gctggagacg tcactgaagc ggctgcagtg tccccgagtg gacctcttct acctgcatat
361 gccagaccac agcaccccgg tggaagagac actgcgtgcc tgccaccagc tgcaccagga
421 gggcaagttc atggagcttg gcctctccaa ctatgcagcc tgggaagtgg ccgagatctg
481 taccctctgc aagagcaacg gctggatcct gcccactgtg taccagggca tgtacaatgc
541 catcacccgg caggtggaaa cggagctctt cccctgcctc aggcactttg gactgaggtt
601 ctatgccttc aaccctctgg ctgggggcct gctgaccggc aagtacaagt atgaggacaa
661 gaatgggaaa cagcccgtgg gccgcttctt tgggaatacc tgggcagaga tgtacaggaa
721 tcgctactgg aaggagcacc actttgaggg cattgccctg gtggagaagg ccctgcaggc
781 cgcgtatggc gccagcgccc ccagcatgac ctcggccacc ctccggtgga tgtaccacca
841 ctcacagctg cagggtgccc acggggacgc ggtcatcctg ggcatgtcca gcctggagca
901 gctggagcag aacttggcag cggcagagga agggcccctg gagccggctg tcgtggatgc
961 ctttaatcaa gcctggcatt tggttactca cgaatgtccc aactacttcc gctaggccca
1021 tcgtttctca ggctgcccaa ggctcttctg taacatcttt tgttactcac attttcttta
1081 atttagaact gcctcagtaa attcttaggg atggaagtat ttggacaaaa acctaataga
1141 agagtcacca ccaaatgaag aataaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaaaa aaa
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