LOCUS BC030978 2260 bp mRNA linear HUM 03-JAN-2005
DEFINITION Homo sapiens solute carrier family 22 (organic cation transporter),
member 2, mRNA (cDNA clone IMAGE:4608270), complete cds.
ACCESSION BC030978
VERSION BC030978.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2260)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2260)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (03-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 41 Row: f Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23510411
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2260
/db_xref="H-InvDB:HIT000259021"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4608270"
/tissue_type="Kidney"
/clone_lib="NIH_MGC_75"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2260
/gene="SLC22A2"
/gene_synonym="OCT2"
/db_xref="GeneID:6582"
/db_xref="MIM:602608"
CDS 175..903
/gene="SLC22A2"
/gene_synonym="OCT2"
/codon_start=1
/product="SLC22A2 protein"
/protein_id="AAH30978.1"
/db_xref="GeneID:6582"
/db_xref="MIM:602608"
/translation="MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLG
FTPDHRCRSPGVAELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFD
CVDPLASLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGF
FIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGW
LIGYILSKNVCACNCENKATSLPK"
BASE COUNT 646 a 515 c 481 g 618 t
ORIGIN
1 gcacctttga agtcagctgg accaaggaaa ggccctgccc tgaaggctgg tcacttgcag
61 aggtaaactc ccctctttga cttctggcca gggtttgtgc tgagctggct gcagccgctc
121 tcagcctcgc tccgggcacg tcgggcagcc tcgggccctc ctgcctgcag gatcatgccc
181 accaccgtgg acgatgtcct ggagcatgga ggggagtttc actttttcca gaagcaaatg
241 tttttcctct tggctctgct ctcggctacc ttcgcgccca tctacgtggg catcgtcttc
301 ctgggcttca cccctgacca ccgctgccgg agccccggag tggccgagct gagtctgcgc
361 tgcggctgga gtcctgcaga ggaactgaac tacacggtgc cgggcccagg acctgcgggc
421 gaagcctccc caagacagtg taggcgctac gaggtggact ggaaccagag caccttcgac
481 tgcgtggacc ccctggccag cctggacacc aacaggagcc gcctgccact gggcccctgc
541 cgggacggct gggtgtacga gacgcctggc tcgtccatcg tcaccgagtt taacctggta
601 tgtgccaact cctggatgtt ggacctattc cagtcatcag tgaatgtagg attctttatt
661 ggctctatga gtatcggcta catagcagac aggtttggcc gtaagctctg cctcctaact
721 acagtcctca taaatgctgc agctggagtt ctcatggcca tttccccaac ctatacgtgg
781 atgttaattt ttcgcttaat ccaaggactg gtcagcaaag caggctggtt aataggctac
841 atcctgagta agaatgtttg tgcttgcaac tgtgagaaca aagcaacctc gctgccaaaa
901 tagagtcagg tggggggcgg catgcaggaa aagggaccca gcttcaagac aatattgaga
961 gattttttta tttctgtatc aaaagaattc ctaaaagcat atcaactcat tcagcattcc
1021 tccttataaa ctaaaaaaat gaaggcagaa acaagggtaa acataatgcc acccagattc
1081 ttatgtaact tttttggaat ttttgttttc tgtaccctgg agtattgtgt ggaaagaaaa
1141 ttcatcctac cagacctatt cataaagaag aatcagtgat gagagatata gtagatttat
1201 aaaggacttt aatactttgc aaaaatctat tctagtgaac tacaattatc ctcaacttac
1261 acataaggaa actgaaaaca caagtactgt agtcaaccta ggttactcag ccagccattt
1321 ttaggacgag gaatataact tacatcctat tccttagtag ccagagttac agttaagttc
1381 catatactat aagagaatat ttgacttcta acatcatagc atctttatag caatattctc
1441 actatggctg ataccaacgg gttgaaccac cagcttgtaa aattccccag catgtaaaac
1501 cagttcctgc cagccagcac tagctgattc cagccctctg ctaagttacc aagccattta
1561 tacaaataaa caaataggac ttgcaagata aatgttaaac ccatgtaaga gaacaagtta
1621 tactcaggtg ttcatttaca taaaaatcat ctacggtcta aatttaatgt ttgattcatt
1681 tgttcaggtc ttgagttact actctaggtc aaaatcttgc atgtatctga aatacaattg
1741 catcatgaaa attataaatc aaatgtgttt gcttatgttg gcaggccttt catcccatct
1801 acaatgggac tataagattt attaattagt aaaacagcaa tagttataac aaaataaaaa
1861 ccaaaaaaca cttaaaaata ttcagagagt tgcatagaat attctagaat ttgtctatat
1921 ttttgaggtt ggcgttctag tttcctgata gctggacagc caactcatta ttgtattgaa
1981 ttgcattaac cattcaaatt ctctctgcag ttacagaatt tgttgggcgg agatatcgga
2041 gaacagtggg gattttttac caagttgcct atacagttgg gctcctggtg ctagctgggg
2101 tggcttacgc acttcctcac tggaggtggt tgcagttcac agttgctctg cccaacttct
2161 tcttcttgct ctattactgg taagtccatt tggaataaaa aggaaataaa tcaaagtatt
2221 ttattctgcc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
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