LOCUS BC030808 2902 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens zinc finger, FYVE domain containing 16, mRNA (cDNA
clone MGC:22300 IMAGE:4701661), complete cds.
ACCESSION BC030808
VERSION BC030808.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2902)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2902)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 37 Row: a Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7662047.
FEATURES Location/Qualifiers
source 1..2902
/db_xref="H-InvDB:HIT000041147"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22300 IMAGE:4701661"
/tissue_type="Lung"
/clone_lib="NIH_MGC_77"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2902
/gene="ZFYVE16"
/gene_synonym="ENDOFIN"
/gene_synonym="KIAA0305"
/db_xref="GeneID:9765"
CDS 111..2540
/gene="ZFYVE16"
/gene_synonym="ENDOFIN"
/gene_synonym="KIAA0305"
/codon_start=1
/product="ZFYVE16 protein"
/protein_id="AAH30808.1"
/db_xref="GeneID:9765"
/translation="MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVS
SELASSQRTSLLPKDQECVNSCASSETSYGTNESSLNKKTLKGLTSIQNEKNVTGLDL
LSSVDGGTSDEIQPLYMGRCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADS
LIGLDLSSVSDTPCVSSTDHDSDTVREQQNDTSSELQNREIGGIKELGIKVDTTLSDS
YNYSGTENLKDKKIFNQLESIVDFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVG
LVKEEVDVAVITAAECLKEEGKTSALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQED
KTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSSKDVPSSLSCLPASGSMCGSLIESK
ARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEG
MEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTHVPESSDCCEGFINTFSSNDM
DGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDM
KGLDDGNINNIYFNAEAGAIGESHGINIICETVDKQNTIENGLSLGEKSTIPVQQGLP
TSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRSSKDLNKPDVPDTIESEPSTAD
TVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTANEDSVPENTCKEGLVLGQK
QPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCV
VCYETISKGEC"
misc_feature 2334..2528
/gene="ZFYVE16"
/gene_synonym="ENDOFIN"
/gene_synonym="KIAA0305"
/note="FYVE; Region: FYVE zinc finger. The FYVE zinc
finger is named after four proteins that it has been found
in: Fab1, YOTB/ZK632.12, Vac1, and EEA1. The FYVE finger
has been shown to bind two Zn++ ions. The FYVE finger has
eight potential zinc coordinating cysteine positions. Many
members of this family also include two histidines in a
motif R+HHC+XCG, where + represents a charged residue and
X any residue. We have included members which do not
conserve these histidine residues but are clearly related"
/db_xref="CDD:pfam01363"
BASE COUNT 997 a 497 c 575 g 833 t
ORIGIN
1 ggggtagctc ttcactcctc agcgcgacgt cgtgtcgagt tcccaaaaag ctccgcaggg
61 gctgtaggga ggcatacaag aattaaattc tgaataagtc tgcaggtagg atggacagtt
121 attttaaagc agctgtcagt gacttggaca aactccttga tgattttgaa cagaacccag
181 atgaacaaga ttatctccaa gatgtacaaa atgcatatga ttctaaccac tgctcagttt
241 cttcagagtt ggcttcctca cagcgaactt cattgctccc aaaagaccaa gagtgcgtta
301 atagttgtgc ctcatcagaa acaagctatg gaacaaatga gagttccctg aataaaaaaa
361 cactcaaggg acttacttct atacaaaatg aaaaaaatgt aacaggactt gatcttcttt
421 cttctgtgga tggtggtact tcagatgaaa tccagccgtt atatatggga cgatgtagta
481 aacctatctg tgatctgata agtgacatgg gtaacttagt tcatgcaacc aatagtgaag
541 aagatattaa aaaattattg ccagatgatt ttaagtctaa tgcagattcc ttgattggat
601 tggatttatc ttcagtgtca gatactccct gtgtttcttc aacagaccat gatagcgata
661 ctgtcagaga acaacagaat gataccagtt ctgaattaca aaatagagaa atcggaggaa
721 tcaaagaatt gggtataaaa gtagatacaa cactttcaga ttcctataat tacagtggaa
781 cagaaaattt aaaagataaa aagatcttta atcagttaga atcaattgtt gattttaaca
841 tgtcatctgc tttgactcga caaagttcca aaatgtttca tgccaaagac aagctacaac
901 acaagagcca gccatgtgga ttactaaaag atgttggctt agtaaaagag gaagtagatg
961 tggcagtcat aactgccgca gaatgtttaa aagaagaggg caagacaagt gctttgacct
1021 gcagccttcc gaaaaatgaa gatttatgct taaatgattc aaattcaaga gatgaaaatt
1081 tcaaattacc tgacttttcc tttcaggaag ataagactgt tataaaacaa tctgcacaag
1141 aagactcaaa aagtttagac cttaaggata atgatgtaat ccaagattcc tcttcagctt
1201 tacatgtttc cagtaaagat gtgccgtcct cattgtcctg tcttcctgcg tctgggtcta
1261 tgtgtggatc attaattgaa agtaaagcac ggggtgattt tttacctcag catgaacata
1321 aagataatat acaagatgca gtgactatac atgaagaaat acagaacagt gttgttctag
1381 gtggggaacc attcaaagag aatgatcttt tgaaacagga aaaatgtaaa agcatactcc
1441 ttcagtcatt aattgaaggg atggaagaca gaaagataga tcctgaccag acagtaatca
1501 gagctgagtc tttggatggt ggtgacacca gttctacagt tgtagaatct caagaggggc
1561 tttctggcac tcatgtccca gagtcttctg attgttgtga aggttttatt aatacttttt
1621 caagcaatga tatggatggg caagacttag attactttaa tattgatgaa ggcgcaaaaa
1681 gtggcccact aattagtgat gctgaacttg atgcctttct gacagaacag tatcttcaga
1741 ccactaacat aaagtctttt gaagaaaatg taaatgactc taaatcgcaa atgaatcaga
1801 tagatatgaa aggcttagat gatggaaaca tcaataatat atatttcaat gcagaagcag
1861 gagctattgg ggaaagtcat ggtattaata taatttgtga aacagttgat aaacaaaata
1921 caatagaaaa tggcctttct ttaggagaaa aaagcactat tccagttcaa caagggttac
1981 ctaccagtaa gtctgagatt acaaatcaat tatcagtctc tgatattaac agtcaatctg
2041 ttggaggggc cagacctaag caattgttta gccttccatc aagaacaagg agttcaaagg
2101 acctgaataa gccagatgtt ccagatacaa tagaaagtga acccagcaca gcagataccg
2161 ttgttccaat cacttgtgct atagattcta cagctgatcc acaggttagc ttcaactcta
2221 attacattga tatagaaagt aattctgaag gtggatctag tttcgtaact gcaaatgaag
2281 attctgtacc tgaaaacact tgcaaagaag gcttggtttt gggccagaaa cagcctactt
2341 gggttcctga ttcagaagct ccaaactgta tgaactgcca agtcaaattt acttttacca
2401 aacggcgaca ccattgccga gcatgtggga aagtattttg tggtgtctgt tgtaatagga
2461 agtgtaaact gcaatatcta gaaaaggaag caagagtatg tgtagtctgc tatgaaacta
2521 ttagtaaagg tgagtgttaa cttgatatat tttcttccag taattgaata tatcttaaaa
2581 ttaattggat tgtgacaaag ataaacttct ttattttctt aaggcaagga cctagtgttg
2641 aattatctgg cttaggtggg acatcccaag gcttggtttc tcttcttttt gttccactct
2701 cacaattaat actaccaatc tggaaaggaa gcattcagtt tctggagtgg cagttcatta
2761 acttttaaca ggtaccaagt ccctaaatgc tgcatttcat ctgcctattt gtttttgtca
2821 tcatcattgt catgttaatc atcttaatct aaataaacac ttacagatac ctaaaaaaaa
2881 aaaaaaaaaa aaaaaaaaaa aa
//