LOCUS BC030594 3220 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens CD46 molecule, complement regulatory protein, mRNA
(cDNA clone MGC:26544 IMAGE:4823040), complete cds.
ACCESSION BC030594
VERSION BC030594.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3220)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3220)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC030594.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: e Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27502426.
FEATURES Location/Qualifiers
source 1..3220
/db_xref="H-InvDB:HIT000041060"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26544 IMAGE:4823040"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3220
/gene="CD46"
/gene_synonym="MGC26544"
/gene_synonym="TLX"
/gene_synonym="TRA2.10"
/db_xref="GeneID:4179"
/db_xref="HGNC:HGNC:6953"
/db_xref="MIM:120920"
CDS 116..1270
/gene="CD46"
/gene_synonym="MGC26544"
/gene_synonym="TLX"
/gene_synonym="TRA2.10"
/codon_start=1
/product="CD46 molecule, complement regulatory protein"
/protein_id="AAH30594.1"
/db_xref="GeneID:4179"
/db_xref="HGNC:HGNC:6953"
/db_xref="MIM:120920"
/translation="MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAM
ELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYI
RDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKV
LCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSR
AAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW
DPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAV
IVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG"
BASE COUNT 992 a 566 c 641 g 1021 t
ORIGIN
1 gtgagttggg gattgttgcg tcccatatct ggacccagaa gggacttccc tgctcggctg
61 gctctcggtt tctctgcttt cctccggaga aataacagcg tcttccgcgc cgcgcatgga
121 gcctcccggc cgccgcgagt gtccctttcc ttcctggcgc tttcctgggt tgcttctggc
181 ggccatggtg ttgctgctgt actccttctc cgatgcctgt gaggagccac caacatttga
241 agctatggag ctcattggta aaccaaaacc ctactatgag attggtgaac gagtagatta
301 taagtgtaaa aaaggatact tctatatacc tcctcttgcc acccatacta tttgtgatcg
361 gaatcataca tggctacctg tctcagatga cgcctgttat agagaaacat gtccatatat
421 acgggatcct ttaaatggcc aagcagtccc tgcaaatggg acttacgagt ttggttatca
481 gatgcacttt atttgtaatg agggttatta cttaattggt gaagaaattc tatattgtga
541 acttaaagga tcagtagcaa tttggagcgg taagccccca atatgtgaaa aggttttgtg
601 tacaccacct ccaaaaataa aaaatggaaa acacaccttt agtgaagtag aagtatttga
661 gtatcttgat gcagtaactt atagttgtga tcctgcacct ggaccagatc cattttcact
721 tattggagag agcacgattt attgtggtga caattcagtg tggagtcgtg ctgctccaga
781 gtgtaaagtg gtcaaatgtc gatttccagt agtcgaaaat ggaaaacaga tatcaggatt
841 tggaaaaaaa ttttactaca aagcaacagt tatgtttgaa tgcgataagg gtttttacct
901 cgatggcagc gacacaattg tctgtgacag taacagtact tgggatcccc cagttccaaa
961 gtgtcttaaa gtgtcgactt cttccactac aaaatctcca gcgtccagtg cctcaggtcc
1021 taggcctact tacaagcctc cagtctcaaa ttatccagga tatcctaaac ctgaggaagg
1081 aatacttgac agtttggatg tttgggtcat tgctgtgatt gttattgcca tagttgttgg
1141 agttgcagta atttgtgttg tcccgtacag atatcttcaa aggaggaaga agaaagggaa
1201 agcagatggt ggagctgaat atgccactta ccagactaaa tcaaccactc cagcagagca
1261 gagaggctga atagattcca caacctggtt tgccagttca tcttttgact ctattaaaat
1321 cttcaatagt tgttattctg tagtttcact ctcatgagtg caactgtggc ttagctaata
1381 ttgcaatgtg gcttgaatgt aggtagcatc ctttgatgct tctttgaaac ttgtatgaat
1441 ttgggtatga acagattgcc tgctttccct taaataacac ttagatttat tggaccagtc
1501 agcacagcat gcctggttgt attaaagcag ggatatgctg tattttataa aattggcaaa
1561 attagagaaa tatagttcac aatgaaatta tattttcttt gtaaagaaag tggcttgaaa
1621 tcttttttgt tcaaagatta atgccaactc ttaagattat tctttcacca actatagaat
1681 gtattttata tatcgttcat tgtaaaaagc ccttaaaaat atgtgtatac tactttggct
1741 cttgtgcata aaaacaagaa cactgaaaat tgggaatatg cacaaacttg gcttctttaa
1801 ccaagaatat tattggaaaa ttctctaaaa gttaataggg taaattctct attttttgta
1861 atgtgttcgg tgatttcaga aagctagaaa gtgtatgtgt ggcatttgtt ttcacttttt
1921 aaaacatccc taactgatcg aatatatcag taatttcaga atcagatgca tcctttcata
1981 agaagtgaga ggactctgac agccataaca ggagtgccac ttcatggtgc gaagtgaaca
2041 ctgtagtctt gttgttttcc caaagagaac tccgtatgtt ctcttaggtt gagtaaccca
2101 ctctgaattc tggttacatg tgtttttctc tccctcctta aataaagaga ggggttaaac
2161 atgccctcta aaagtaggtg gttttgaaga gaataaattc atcagataac ctcaagtcac
2221 atgagaatct tagtccattt acattgcctt ggctagtaaa agccatctat gtatatgtct
2281 tacctcatct cctaaaaggc agagtacaaa gtaagccatg tatctcagga aggtaacttc
2341 attttgtcta tttgctgttg attgtaccaa gggatggaag aagtaaatat agctcaggta
2401 gcactttata ctcaggcaga tctcagccct ctactgagtc ccttagccaa gcagtttctt
2461 tcaaagaagc cagcaggcga aaagcaggga ctgccactgc atttcatatc acactgttaa
2521 aagttgtgtt ttgaaatttt atgtttagtt gcacaaattg ggccaaagaa acattgcctt
2581 gaggaagata tgattggaaa atcaagagtg tagaagaata aatactgttt tactgtccaa
2641 agacatgttt atagtgctct gtaaatgttc ctttcctttg tagtctctgg caagatgctt
2701 taggaagata aaagtttgag gagaacaaac aggaattctg aattaagcac agagttgaag
2761 tttatacccg tttcacatgc ttttcaagaa tgtcgcaatt actaagaagc agataatggt
2821 gttttttaga aacctaattg aagtatattc aaccaaatac tttaatgtat aaaataaata
2881 ttatacaata tacttgtata gcagtttctg cttcacattt gattttttca aatttaatat
2941 ttatattaga gatctatata tgtataaata tgtattttgt caaatttgtt acttaaatat
3001 atagagacca gttttctctg gaagtttgtt taaatgacag aagcgtatat gaattcaaga
3061 aaatttaagc tgcaaaaatg tatttgctat aaaatgagaa gtctcactga tagaggttct
3121 ttattgctca ttttttaaaa aatggactct tgaaatctgt taaaataaaa ttgtacattt
3181 ggagatgttt caaaaaaaaa aaagaaaaaa aaaaaaaaaa
//