LOCUS BC030547 2220 bp mRNA linear HUM 25-OCT-2007
DEFINITION Homo sapiens leucine-rich repeats and WD repeat domain containing
1, mRNA (cDNA clone MGC:40401 IMAGE:5170588), complete cds.
ACCESSION BC030547
VERSION BC030547.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2220)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2220)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: e Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23097239.
FEATURES Location/Qualifiers
source 1..2220
/db_xref="H-InvDB:HIT000041040"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40401 IMAGE:5170588"
/tissue_type="Brain, adult medulla"
/clone_lib="NIH_MGC_119"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2220
/gene="LRWD1"
/gene_synonym="DKFZp434K1815"
/db_xref="GeneID:222229"
/db_xref="HGNC:HGNC:21769"
CDS 139..2082
/gene="LRWD1"
/gene_synonym="DKFZp434K1815"
/codon_start=1
/product="leucine-rich repeats and WD repeat domain
containing 1"
/protein_id="AAH30547.1"
/db_xref="GeneID:222229"
/db_xref="HGNC:HGNC:21769"
/translation="MGPLSARLLMQRGRPKSDRLGKIRSLDLSGLELLSEHLDPKLLC
RLTQLQELDLSNNHLETLPDNLGLSHLRVLRCANNQLGDVTALCQFPKLEELSLEGNP
FLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRELTSRVTAHWEKFMATLGPEE
EAEKAQADFVKSAVRDVRYGPESLSEFTQWRVRMISEELVAASRTQVQKANSPEKPPE
AGAAHKPRARLAALKRPDDVPLSLSPSKRACASPSAQVEGSPVAGSDGSQPAVKLEPL
HFLQCHSKNNSPQDLETQLWACAFEPAWEEGATSQTVATCGGEAVCVIDCQTGIVLHK
YKAPGEEFFSVAWTALMVVTQAGHKKRWSVLAAAGLRGLVRLLHVRAGFCCGVIRAHK
KAIATLCFSPAHETHLFTASYDKRIILWDIGVPNQDYEFQASQLLTLDTTSIPLRLCP
VASCPDARLLAGCEGGCCCWDVRLDQPQKRRVCEVEFVFSEGSEASGRRVDGLAFVNE
DIVASKGSGLGTICLWSWRQTWGGRGSQSTVAVVVLARLQWSSTELAYFSLSACPDKG
IVLCGDEEGNVWLYDVSNILKQPPLLPAALQAPTQILKWPQPWALGQVVTKTMVNTVV
ANASFTYLTALTDSNIVAIWGRM"
BASE COUNT 424 a 705 c 708 g 383 t
ORIGIN
1 gttaacgccc acgggctcgc gcggcgccgc ctcctgggct cagttaccgc ggacgccagt
61 gccgggctcc aggagacgca gggcgacgcc acacgccggg gtggccgact gggtcagcgc
121 gggctgcgcc tcctcgccat gggccccctc tcggcgcggc tgctaatgca gcgcgggcgc
181 cccaagagcg accggctggg gaagatccgg agtctggacc tgtcaggatt ggagctgctt
241 tccgagcacc tggaccccaa actcctgtgc cgcctgacgc agctgcagga gcttgacctg
301 tctaacaacc acctggagac gctgccggac aacctgggcc tgtcccacct gcgtgtcctc
361 cgctgcgcca acaaccagct gggggatgtt actgccttgt gccagttccc caagctcgag
421 gaactcagcc tggagggcaa ccccttcctg acggtcaatg acaacctgaa agtctccttt
481 ctcctgccca cgctccgtaa ggtcaatggc aaggatgcgt cctcaactta ctctcaggtg
541 gagaacctga atcgggagct gaccagcagg gtcacagctc actgggagaa gttcatggcc
601 acactgggtc ctgaagagga ggctgagaag gcccaggcgg actttgtgaa gtcggctgtc
661 agggatgtcc gctacgggcc cgagtccctc agcgagttca cccagtggcg ggtgcggatg
721 atctctgagg agctggtggc cgccagtagg acccaggtgc aaaaggctaa cagcccagag
781 aagcccccag aagctggagc tgcccacaag cccagggcca gactggcggc cttgaaacgg
841 ccagacgacg tcccactcag cctctctccc agcaagcggg cgtgtgcctc cccgtcggcc
901 caggtggagg gcagccctgt ggcaggctcc gatggcagcc agcctgctgt gaagctggag
961 cccctgcact tcctgcagtg ccacagcaag aacaacagcc cccaggacct cgagacccag
1021 ctgtgggcct gtgccttcga gccggcctgg gaggaggggg ccacatccca gaccgtggcc
1081 acgtgcggcg gggaggctgt gtgcgtaatt gattgccaga cgggcatcgt gctccacaag
1141 tacaaggcac ccggcgagga gttcttttct gtggcctgga ccgctctgat ggtggtcaca
1201 caggctggcc acaagaagcg ctggagtgtg ctggcggctg caggcctacg gggcctggtc
1261 cggctgctgc acgtgcgtgc cggcttctgc tgcggggtca tccgagccca caagaaggcc
1321 atcgccaccc tgtgcttcag ccccgcccac gagacccatc tcttcacggc ctcctatgac
1381 aagcggatca tcctctggga catcggggtg cccaaccagg actacgaatt ccaggccagc
1441 cagctgctca cactggacac cacctctatc cccctgcgcc tctgccctgt cgcctcctgc
1501 ccggacgccc gcctgctggc cggctgcgag ggcggctgct gctgctggga cgtgcggctg
1561 gaccagcccc aaaagaggag ggtgtgtgaa gtggaattcg tcttctctga gggctccgag
1621 gcatctggac ggagagtgga tgggctggca tttgtgaatg aggacatcgt ggcctccaag
1681 gggagcggcc tgggcaccat ctgcctgtgg agctggaggc agacgtgggg gggccggggc
1741 agccagtcca cggtggcagt ggtggtcctg gcgcggctgc aatggtcgtc caccgagttg
1801 gcctacttct cgctcagcgc ctgccctgat aaggggattg tgctctgtgg ggatgaggag
1861 ggcaacgtgt ggctctacga cgtcagcaac atcctgaagc agccacccct gctgccggca
1921 gccctgcagg cccccacaca gatcctgaag tggccccagc cctgggccct tggccaggtg
1981 gtgaccaaga ccatggtgaa cacagtggtg gccaatgcct ccttcaccta cctcaccgcc
2041 ctgacggact ccaacatcgt agccatctgg gggaggatgt agcctcacac catcgcaaag
2101 gaccagggac acagctaact aacttattca gctttgggcc gatgggggtg ggggggggtc
2161 tttcagtgaa tatttttatt aaactctact gtggacaaaa aaaaaaaaaa aaaaaaaaaa
//