LOCUS BC028691 3815 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 4 (importin alpha 3), mRNA (cDNA
clone MGC:26508 IMAGE:4838709), complete cds.
ACCESSION BC028691
VERSION BC028691.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3815)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3815)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC028691.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: o Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27477125.
FEATURES Location/Qualifiers
source 1..3815
/db_xref="H-InvDB:HIT000040608"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26508 IMAGE:4838709"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3815
/gene="KPNA4"
/gene_synonym="IPOA3"
/gene_synonym="MGC12217"
/gene_synonym="MGC26703"
/gene_synonym="QIP1"
/gene_synonym="SRP3"
/db_xref="GeneID:3840"
/db_xref="HGNC:HGNC:6397"
/db_xref="MIM:602970"
CDS 252..1817
/gene="KPNA4"
/gene_synonym="IPOA3"
/gene_synonym="MGC12217"
/gene_synonym="MGC26703"
/gene_synonym="QIP1"
/gene_synonym="SRP3"
/codon_start=1
/product="karyopherin alpha 4 (importin alpha 3)"
/protein_id="AAH28691.1"
/db_xref="GeneID:3840"
/db_xref="HGNC:HGNC:6397"
/db_xref="MIM:602970"
/translation="MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEH
LLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSD
RNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVP
LFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLR
NVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQ
IQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPAL
LTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAI
SNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIG
NLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPEAIQGGTFGF
NSSANVPTEGFQF"
BASE COUNT 1217 a 680 c 830 g 1088 t
ORIGIN
1 tccgtcgcct tgccgccgcc cggccccaca gttgtctttg ccggagctgc agtcgcgctg
61 gggttagggc gggggggcgg gcggggagag gagaaggccg cggcggaggc aggtgagagg
121 aggaaggaag cggcggcgcg gcgggcacag cagctcaggc ggcggcccgg ttcctgggag
181 tgtcggtgcg gcgcgttggt tggggcggat cccgcggggc ccgggcgggg gaaggagtca
241 ccggcccggc catggcggac aacgagaaac tggacaacca acggctcaag aatttcaaga
301 acaaaggccg cgacttggag actatgagaa gacaacgaaa tgaagttgta gttgaattaa
361 ggaagaataa aagagatgaa catctcttaa agagaaggaa tgtaccacat gaagatatct
421 gtgaagactc tgatatagat ggtgattata gagtgcaaaa tacctctcta gaagctattg
481 ttcaaaatgc ttcaagtgat aaccaaggaa ttcaattaag tgcagttcaa gctgctagga
541 agcttttgtc cagtgatcga aatccaccaa ttgatgactt aataaaatct ggaatattgc
601 ccattttagt ccattgtctt gaaagagatg acaatccttc tttacagttt gaagctgcat
661 gggctttgac aaacattgca tctggaactt ctgaacaaac tcaagcagta gttcagtcca
721 atgctgtgcc acttttcctg aggcttctcc attcacccca tcagaatgtc tgtgagcaag
781 cagtgtgggc attgggaaat atcataggtg atgggcccca gtgtagagat tatgtcataa
841 gtcttggagt tgtgaaacct ttactttcct tcataagtcc atctattcct ataacattct
901 taagaaatgt tacttgggtt atggtcaact tatgtcgcca caaagaccca ccaccaccaa
961 tggaaaccat tcaggagatt cttccagccc tttgtgtttt aattcatcac acagatgtaa
1021 atatactggt agacacagtc tgggccctct cttaccttac tgatgctggc aatgaacaaa
1081 tacagatggt aatagactct ggaatagttc ctcatttggt tcctctgctc agccaccagg
1141 aagttaaagt tcagactgct gcacttagag ctgtgggcaa cattgttact ggaactgatg
1201 agcaaacaca agtagttttg aactgtgatg ctctttcaca cttcccagca ctcctgacac
1261 atcccaaaga gaaaattaat aaagaagcag tgtggttcct ctccaacatc actgcaggaa
1321 atcagcagca ggtacaggca gtaattgatg ccaatcttgt accaatgata atacaccttt
1381 tggataaggg ggattttggc actcaaaaag aagctgcttg ggccataagt aacttaacaa
1441 ttagtggaag gaaagatcaa gtggcttacc ttatccaaca aaatgttatc ccaccttttt
1501 gcaacttgct gactgtaaaa gatgcacaag ttgtgcaagt agtactcgat ggactaagta
1561 atatattaaa aatggctgaa gatgaggcag aaaccatagg caatcttata gaagaatgtg
1621 gagggctgga gaaaattgaa caacttcaaa atcatgaaaa tgaagacatc tacaaattgg
1681 cctatgagat cattgatcag ttcttctctt cagatgatat tgatgaagac cctagccttg
1741 ttccagaggc aattcaaggc ggaacatttg gtttcaattc atctgccaat gtaccaacag
1801 aagggttcca gttttagaaa gatgttgtgg aagttaggta caatgcagca ctgagatata
1861 tatatatata tgtgtgtgtg tatatatata tatatataca tatatataaa aaggtttgat
1921 ccatcaagct tggctcatgg gatctgctgc tgcattaaat cgggaaagaa aatgtgaaga
1981 tttcatttgg aatcacagaa aatgcccaaa tgaggtcaag atggcgagtg ggtgcgagtg
2041 agaatgagtg gcaaaatgta atgaaaactt tacatgaatg cttatttagg ttgttcaaag
2101 taaaaagggc tacaggtcac agatcgtcag tgcctgagaa agaacattga cttactctat
2161 atcaattgag gggaaagtgc agtaccgtca tcttcaagcc ttgtaagcat aaaagagaat
2221 aggctgccca tataagtcaa aggaaaatga gcccaggcct tgctatgaag cagtgtgtga
2281 atggacaatg ttgaatgaat gtctggctca gtgatggaga gccaggttca tctttgaaat
2341 ctagggctct tcactcatga agcagactcc tagtcctgga gtgactgtgt acgagagcgt
2401 ggttgtggtg ctgtatgtga acgcatgcaa gcttgattca ccttcagggg gctgataacc
2461 tagtaaatca tcaaaatgag atcataagtg ttaatgtaca ctggacatga aaacaaagac
2521 tggtttagca gcagacattg gtttactctg cagcctgtgt tttctgtttc cccctttccc
2581 acctccttcc ccccacccaa tccttttttt tttctttttt gcttttcttt tctttttttt
2641 tagtttttat ttactttacc tagtatgcct ttttttagtt gcttctcaag tcagaaaact
2701 tttcaggaag gtttccctgt gcatttgcac cagatgaatg tttgatgcta tgaaaagctt
2761 tccatatcat caaaactaat ttgtgtagat ttttgcatga aaaaaatcat aaatttccct
2821 caaaatagac tgtgttgcag tacacaagtt gccataatag tataaaacag taaaatgtgc
2881 ttaaaaggcc atccttttca ttttcagaga taacataaag atctttgcat gaggtaaatc
2941 tacagcatag ttcattttta gattttgttg agtcctgtaa agaagaagaa gaaaaaagtt
3001 tcagttgtgg tagaataccg tgctgtgttt aaatgttact tgttttcaaa ctttgttttc
3061 tatgaaaatg atatggaaac ttctaaaatg gaatttggtg catatgtact gctgaataaa
3121 gaccgatgaa gaggtttgag tagatgtaca aatcaagtaa tggtttgaac acctttaata
3181 atatgcctaa tctgttcaat tgttttagaa tctttttatc ttagatgtag gcagccatga
3241 acaatctatt ttgagccact ttagggagaa aactttgtat ttttaaaact tgcataaaag
3301 ttatgcaagt ggtttttata aattggaata atacctcagt tttgaggtta tgcacactaa
3361 attaaatgtg acataaatta atttgtaaaa aaagaactct ttataaggtg gctcattgta
3421 ggaaatcctg tgccttcccc tttgagcaca agtgttgcat gaacaacagt ttgctataag
3481 aaacatacca gattagccac cattagcatc tatatctact ttgtgtttaa aaatcaactg
3541 gtaattctga aacactgtag aatggataaa aattattttg tgatcataac tctttgttga
3601 actagagtat ttttgcagca ttccttgtca tcagaaacat ggttaaagtt taaaactaga
3661 agcagcagaa aactagcttg taaaatttat ccaagtagag tgcaggctag gctgtcttgg
3721 ggaaataaac attaaaactt aaagcaatgt tttaaaaaaa aaaaaaaaaa aaaaaaaaaa
3781 aaaaaaaaaa aaaaaaaaag aaaaaaaaaa aaaaa
//