LOCUS BC028364 3471 bp mRNA linear HUM 16-FEB-2007
DEFINITION Homo sapiens F-box and WD repeat domain containing 10, mRNA (cDNA
clone MGC:26596 IMAGE:4827344), complete cds.
ACCESSION BC028364
VERSION BC028364.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3471)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3471)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC028364.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 34 Row: a Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40353211.
FEATURES Location/Qualifiers
source 1..3471
/db_xref="H-InvDB:HIT000040537"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26596 IMAGE:4827344"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3471
/gene="FBXW10"
/gene_synonym="Fbw10"
/gene_synonym="HREP"
/gene_synonym="SM25H2"
/gene_synonym="SM2SH2"
/db_xref="GeneID:10517"
/db_xref="HGNC:HGNC:1211"
/db_xref="MIM:604596"
CDS 220..3405
/gene="FBXW10"
/gene_synonym="Fbw10"
/gene_synonym="HREP"
/gene_synonym="SM25H2"
/gene_synonym="SM2SH2"
/codon_start=1
/product="FBXW10 protein"
/protein_id="AAH28364.1"
/db_xref="GeneID:10517"
/db_xref="HGNC:HGNC:1211"
/db_xref="MIM:604596"
/translation="MENLESRLKNAPYFRCEKGTDSIPLCRKCETCVLAWKIFSTKEW
FCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVV
KSSLNQMLDKTVEQKMKEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLF
LREENNISGLNQDITDVCFSPEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHLLG
AASNPEEPWRNSLRCISEMNRLFSGKGDITKPGYDPCNLLVDLDDIRDLSSGFSKYLD
FIRYLPIHLSKYILSMLGCMRGFPRHLPSWPSSGVSGSIFFFPGMLDRHTLNKCASVS
QHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGKSMR
VKHPKWKLRTKNEYNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNRVIHYS
GGDLIAVSSNRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRY
WDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLKTFRHKDPI
LATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGL
VMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLKA
NGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQYAVEKTKQKKNKEKEEEKEENS
LMEILSKCNIQVHSPRESVSSKQTVIQELLPGKPPKSRVLLKPAKFSSDDVEKAQKQG
QLETPGKLPSHPKKKSWKIPMSPDQFLLTVSALQHAHNSGEFAYPCRPQTEITDVWGP
SISYPRKVLNFKGKSIQRAVDRLRLSNPPIDVKRTSIPLEIQKLQPNLKISLHSPRVQ
STIPQPMIIRSRFSGSLKGGDQVTSSIERAVCSTGPLTSMQVIKPNRMLAPQVGTATL
SLKKERPRIYTALDPFRVNTEFVLLTVKEEKEHQEAKMKEYQARESTGVVDPGKVSKA
AWIRKIKGLPIDNFTKQGKTAAPELGQNVFI"
BASE COUNT 1005 a 806 c 845 g 815 t
ORIGIN
1 gtttccaagg aggtctgtac aaaaagccag acttctgctg gcagttactg agagagatag
61 gctttccatc catggcagcc atttactttt gctctgggag acgtttgtaa tagaaaaggc
121 acaactgggg tatttattca ttccccccgt tcctctagtg tttggtggcg ttgccgttgc
181 aagtgcgcag ggctaaaatg aactggttat cttaggatca tggaaaacct ggaatcaagg
241 ctcaagaatg ccccctattt tcgttgtgag aagggaaccg attccatccc tctatgccgg
301 aagtgtgaga cgtgtgtctt agcctggaag atcttctcta ccaaagagtg gttctgcagg
361 atcaatgaca tatcacagag gaggtttcta gttggcattc tgaagcagtt aaatagctta
421 tatttgttac actatttcca aaatatcctt cagaccacac agggaaagga tttcatctat
481 aacaggtccc ggatcaacct cagcaagaaa gaggggaaag ttgtgaagtc ctccttgaac
541 caaatgttgg ataaaacagt agaacagaag atgaaagaga tcttgtactg gtttgcgaac
601 agcacccagt ggaccaaggc gaattatact ctcttactgc tgcagatgtg caaccccaaa
661 ttactgctca ctgctgccaa tgtgatcaga gtcctgtttc tgagagagga gaacaatatc
721 tcagggctca atcaagacat cacagatgtg tgtttttccc ctgagaaaga ccacagctcc
781 aagtctgcga cctcacaagt ctattggaca gccaaaactc agcacacatc ccttcctttg
841 tccaaagccc cagaaaatga acacttgctt ggggcagcat ctaaccctga ggaaccatgg
901 aggaattcac tccggtgtat atccgaaatg aataggctgt tttctggaaa aggagacata
961 accaagccag ggtacgatcc ctgcaatcta ttggttgacc tggatgacat cagagacctg
1021 tcttctgggt tcagcaaata cctagacttc atccgttacc tgcccatcca cctctccaag
1081 tacattctaa gtatgctggg gtgtatgagg ggatttccca gacacctccc atcttggccc
1141 agttctgggg tttctgggtc catctttttt tttccaggaa tgctggatag acacaccctg
1201 aacaagtgcg cctctgtgag ccagcactgg gccgccatgg ctcaacaggt caagatggac
1261 ttgtcagcgc acggcttcat tcagaaccag attaccttct tgcaggggtc ctacacaaga
1321 ggaattgatc ctaattatgc caataaggtt tctatcccag ttcctaaaat ggtagatgac
1381 gggaagagca tgcgtgtgaa acatccgaag tggaagctga gaacgaagaa tgagtacaac
1441 ctgtggactg cataccagaa cgaggaaacg cagcaggtcc tgatagagga gagaaatgtt
1501 ttctgtggga cctacaatgt tcgcattctc tctgacacgt gggatcaaaa ccgagtcatc
1561 cactattccg ggggagatct gatagctgtg tcatctaatc gaaagatcca tcttctggac
1621 atcatacaag tgaaagcgat acccgttgaa ttccgaggcc atgctgggag tgtccgggcc
1681 ctcttcctgt gtgaggagga aaactttctc ctaagcggga gctatgacct aagtatcaga
1741 tactgggatc tgaaaagtgg ggtttgcaca cgaatcttcg gtggtcacca ggggactatc
1801 acttgcatgg acttgtgtaa gaacaggctc gtatctggag gaagagattg ccaggtaaaa
1861 gtatgggatg tagacacagg gaagtgcctg aagacgttta gacacaaaga ccccatcttg
1921 gccaccagga tcaatgatac ctacattgtg agcagctgtg agcgagggct ggtgaaagtg
1981 tggcacattg ccatggccca gttggtaaag actctcagtg gccatgaggg agccgtgaaa
2041 tgcctgttct ttgaccagtg gcatctcctc tcaggaagta ctgatggcct ggtcatggcc
2101 tggagcatgg tggggaagta cgagcgctgc ctgatggcct tcaagcatcc caaggaggtg
2161 ctcgacgtgt ccctcctctt cctccgggtc atcagcgcct gtgcagatgg caagatccga
2221 atttacaatt tcctcaacgg gaactgtatg aaggtgttaa aagccaatgg cagaggtgat
2281 cctgtgctgt ccttctttat tcagggcaac aggatggtgg tcaacacaga gagcaatgtt
2341 ctcatgttcc agtttgagca cataaagtgg cagtatgccg tggaaaaaac gaaacaaaag
2401 aagaataagg agaaagagga ggaaaaagaa gaaaatagtc tcatggaaat tctctctaag
2461 tgtaatattc aggttcacag cccaagagag tctgtatcca gtaaacaaac tgtgatccaa
2521 gagctcctac caggcaaacc tcccaagtcc cgagtactcc tgaagccggc caagttctct
2581 tcagatgatg tggagaaagc acaaaaacaa ggacaattgg aaactcctgg aaaactgccc
2641 agtcacccaa agaaaaagtc ttggaaaatc cctatgtcac ctgaccaatt cctcctgact
2701 gttagcgccc tgcagcacgc ccataattcc ggggaatttg cctatccctg taggccccaa
2761 acagaaatta ctgatgtctg gggaccttca atttcatacc caaggaaggt cttgaatttc
2821 aaaggaaaat caatccaacg tgcagttgat cggttgagat tgagcaatcc tcctatagat
2881 gtgaaacgaa ccagtattcc ccttgaaatc cagaaactgc agcccaactt gaagatctct
2941 ttgcacagtc ctagagtcca gtccaccata ccccagccca tgattatccg ctccaggttc
3001 tctggcagct taaagggtgg agaccaagtg accagttcaa ttgaaagggc tgtgtgcagt
3061 acgggtcccc tgaccagtat gcaggtcatt aaaccaaacc gcatgctagc tccacaagtg
3121 ggcacagcca ccctgtctct taagaaagaa cggcctcgca tctatacagc ccttgatcct
3181 tttagagtga acactgagtt cgtgctgttg accgtgaagg aggagaagga gcaccaggaa
3241 gccaagatga aggaatatca ggccagggag tccactggag tggttgatcc aggaaaagtc
3301 agcaaagctg catggatcag gaagatcaaa ggcctgccta ttgataattt cacgaagcaa
3361 gggaaaacag cggcccctga acttggacaa aatgtattta tctaaaccag ccttgggaaa
3421 ttacaatgtt ttacaataaa cagaaagcca agcggaaaaa aaaaaaaaaa a
//