LOCUS BC028298 1280 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens retinol dehydrogenase 5 (11-cis/9-cis), mRNA (cDNA
clone MGC:24918 IMAGE:4942311), complete cds.
ACCESSION BC028298
VERSION BC028298.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1280)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1280)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: p Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50726951.
FEATURES Location/Qualifiers
source 1..1280
/db_xref="H-InvDB:HIT000040515"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24918 IMAGE:4942311"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1280
/gene="RDH5"
/db_xref="GeneID:5959"
/db_xref="HGNC:HGNC:9940"
/db_xref="MIM:601617"
CDS 143..1099
/gene="RDH5"
/codon_start=1
/product="retinol dehydrogenase 5 (11-cis/9-cis)"
/protein_id="AAH28298.1"
/db_xref="GeneID:5959"
/db_xref="HGNC:HGNC:9940"
/db_xref="MIM:601617"
/translation="MWLPLLLGALLWAVLWLLRDRQSLPASNALVFITGCDSGFGRLL
ALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKE
AGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVIN
ITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESL
EKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARH
PRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY"
BASE COUNT 275 a 377 c 359 g 269 t
ORIGIN
1 cagtagttag tgtgggaggc tgggaagact gggagcagtc tcttaaacaa aagcaaaaga
61 ataagcttcg ggcgctgtag tacctgccag ctttcgccac aggagcctag gctgccacct
121 gtaggtcact tgggctccag ctatgtggct gcctcttctg ctgggtgcct tactctgggc
181 agtgctgtgg ttgctcaggg accggcagag cctgcccgcc agcaatgccc ttgtcttcat
241 caccggctgt gactcaggct ttgggcgcct tctggcactg cagctggacc agagaggctt
301 ccgagtcctg gccagctgcc tgaccccctc cggggccgag gacctgcagc gggtggcctc
361 ctcccgcctc cacaccaccc tgttggatat cactgatccc cagagcgtcc agcaggcagc
421 caagtgggtg gagatgcacg ttaaggaagc agggcttttt ggtctggtga ataatgctgg
481 tgtggctggt atcatcggac ccacaccatg gctgacccgg gacgatttcc agcgggtgct
541 gaatgtgaac acaatgggtc ccatcggggt cacccttgcc ctgctgcctc tgctgcagca
601 agcccggggc cgggtgatca acatcaccag cgtcctgggt cgcctggcag ccaatggtgg
661 gggctactgt gtctccaaat ttggcctgga ggccttctct gacagcctga ggcgggatgt
721 agctcatttt gggatacgag tctccatcgt ggagcctggc ttcttccgaa cccctgtgac
781 caacctggag agtctggaga aaaccctgca ggcctgctgg gcacggctgc ctcctgccac
841 acaggcccac tatggggggg ccttcctcac caagtacctg aaaatgcaac agcgcatcat
901 gaacctgatc tgtgacccgg acctaaccaa ggtgagccga tgcctggagc atgccctgac
961 tgctcgacac ccccgaaccc gctacagccc aggttgggat gccaagctgc tctggctgcc
1021 tgcctcctac ctgccagcca gcctggtgga tgctgtgctc acctgggtcc ttcccaagcc
1081 tgcccaagca gtctactgaa tccagccttc cagcaagaga ttgtttttca aggacaagga
1141 ctttgattta tttctgcccc caccctggta ctgcctggtg cctgccacaa aataagcact
1201 aacaaaagtg tattgtttaa aaaataaaaa gaaggtgggc agaaatgtgc ccagtggaaa
1261 aaaaaaaaaa aaaaaaaaaa
//