LOCUS BC028292 3001 bp mRNA linear HUM 30-MAR-2004
DEFINITION Homo sapiens podocan, mRNA (cDNA clone MGC:24995 IMAGE:4938380),
complete cds.
ACCESSION BC028292
VERSION BC028292.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3001)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3001)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: o Column: 11.
FEATURES Location/Qualifiers
source 1..3001
/db_xref="H-InvDB:HIT000050942"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24995 IMAGE:4938380"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3001
/gene="PODN"
/gene_synonym="MGC24995"
/gene_synonym="PCAN"
/gene_synonym="SLRR5A"
/db_xref="GeneID:127435"
CDS 769..1977
/gene="PODN"
/gene_synonym="MGC24995"
/gene_synonym="PCAN"
/gene_synonym="SLRR5A"
/codon_start=1
/product="PODN protein"
/protein_id="AAH28292.1"
/db_xref="GeneID:127435"
/translation="MFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPP
GAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVL
LHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNAL
ERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKL
RLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRL
RSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDST
PNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEE
EEEEEEEETR"
misc_feature 835..1386
/gene="PODN"
/gene_synonym="MGC24995"
/gene_synonym="PCAN"
/gene_synonym="SLRR5A"
/note="LRR_RI; Region: Leucine-rich repeats (LRRs),
ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29
residue sequence motifs present in many proteins that
participate in protein-protein interactions and have
different functions and cellular locations. LRRs
correspond to structural units consisting of a beta strand
(LxxLxLxxN/CxL conserved pattern) and an alpha helix. This
alignment contains 12 strands corresponding to 11 full
repeats, consistent with the extent observed in the
subfamily acting as Ran GTPase Activating Proteins
(RanGAP1)"
/db_xref="CDD:cd00116"
BASE COUNT 649 a 986 c 828 g 538 t
ORIGIN
1 gcccgagccc gcggagcgca gctgagactg ggggagcgcg ttcggcctgt ggggcgccgc
61 tcggcgccgg ggcgcagcag gttccgtcag ccctggcgcc caggcgcatc tgactcggca
121 ccccctgcag gcaccatggc ccagagccgg gtgctgctgc tcctgctgct gctgccgcca
181 cagctgcacc tgggacctgt gcttgccgtg agggccccag gatttggccg aagtggcggc
241 cacagcctga gccccgaaga gaacgaattt gcggaggagg agccggtgct ggtactgagc
301 cctgaggagc ccgggcctgg cccagccgcg gtcagctgcc cccgagactg tgcctgttcc
361 caggagggcg tcgtggactg tggcggtatt gacctgcgtg agttcccggg ggacctgcct
421 gagcacacca accacctatc tctgcagaac aaccagctgg aaaagatcta ccctgaggag
481 ctctcccggc tgcaccggct ggagacgctg aacctgcaaa acaaccgcct gacttcccga
541 gggctcccag agaaggcgtt tgagcatctg accaacctca attacctgta cttggccaat
601 aacaagctga ccttggcacc ccgcttcctg ccaaacgccc tgatcagtgt ggactttgct
661 gccaactatc tcaccaagat ctatgggctc acctttggcc agaagccaaa cttgaggtct
721 gtgtacctgc acaacaacaa gctggcagac gccgggctgc cggacaacat gttcaacggc
781 tccagcaacg tcgaggtcct catcctgtcc agcaacttcc tgcgccacgt gcccaagcac
841 ctgccgcctg ccctgtacaa gctgcacctc aagaacaaca agctggagaa gatccccccg
901 ggggccttca gcgagctgag cagcctgcgc gagctatacc tgcagaacaa ctacctgact
961 gacgagggcc tggacaacga gaccttctgg aagctctcca gcctggagta cctggatctg
1021 tccagcaaca acctgtctcg ggtcccagct gggctgccgc gcagcctggt gctgctgcac
1081 ttggagaaga acgccatccg gagcgtggac gcgaatgtgc tgacccccat ccgcagcctg
1141 gagtacctgc tgctgcacag caaccagctg cgggagcagg gcatccaccc actggccttc
1201 cagggcctca agcggttgca cacggtgcac ctgtacaaca acgcgctgga gcgcgtgccc
1261 agtggcctgc ctcgccgcgt gcgcaccctc atgatcctgc acaaccagat cacaggcatt
1321 ggccgcgaag actttgccac cacctacttc ctggaggagc tcaacctcag ctacaaccgc
1381 atcaccagcc cacaggtgca ccgcgacgcc ttccgcaagc tgcgcctgct gcgctcgctg
1441 gacctgtcgg gcaaccggct gcacacgctg ccacctgggc tgcctcgaaa tgtccatgtg
1501 ctgaaggtca agcgcaatga gctggctgcc ttggcacgag gggcgctggc gggcatggct
1561 cagctgcgtg agctgtacct caccagcaac cgactgcgca gccgagccct gggcccccgt
1621 gcctgggtgg acctcgccca tctgcagctg ctggacatcg ccgggaatca gctcacagag
1681 atccccgagg ggctccccga gtcacttgag tacctgtacc tgcagaacaa caagattagt
1741 gcggtgcccg ccaatgcctt cgactccacg cccaacctca aggggatctt tctcaggttt
1801 aacaagctgg ctgtgggctc cgtggtggac agtgccttcc ggaggctgaa gcacctgcag
1861 gtcttggaca ttgaaggcaa cttagagttt ggtgacattt ccaaggaccg tggccgcttg
1921 gggaaggaaa aggaggagga ggaagaggag gaggaggagg aagaggaaac aagatagtga
1981 caaggtgatg cagatgtgac ctaggatgat ggaccgccgg actcttttct gcagcacacg
2041 cctgtgtgct gtgagccccc cactctgccg tgctcacaca gacacaccca gctgcacaca
2101 tgaggcatcc cacatgacac gggctgacac agtctcatat ccccacccct tcccacggcg
2161 tgtcccacgg ccagacacat gcacacacat cacaccctca aacacccagc tcagccacac
2221 acaactaccc tccaaaccac cacagtctct gtcacacccc cactaccgct gccacgccct
2281 ctgaatcatg cagggaaggg tctgcccctg ccctggcaca cacaggcacc cattccctcc
2341 ccctgctgac atgtgtatgc gtatgcatac acaccacaca cacacacatg cacaagtcat
2401 gtgcgaacag ccctccaaag cctatgccac agacagctct tgccccagcc agaatcagcc
2461 atagcagctc gccgtctgcc ctgtccatct gtccgtccgt tccctggaga agacacaagg
2521 gtatccatgc tctgtggcca ggtgcctgcc accctctgga actcacaaaa gctggctttt
2581 attcctttcc catcctatgg ggacaggagc cttcaggact gctggcctgg cctggcccac
2641 cctgctcctc caggtgctgg gcagtcactc tgctaagagt ccctccctgc cacgccctgg
2701 caggacacag gcacttttcc aatgggcaag cccagtggag gcaggatggg agagccccct
2761 gggtgctgct ggggccttgg ggcaggagtg aagcagaggt gatggggctg ggctgagcca
2821 gggaggaagg acccagctgc acctaggaga cacctttgtt cttcaggcct gtgggggaag
2881 ttccgggtgc ctttattttt tattcttttc taaggaaaaa aatgataaaa atctcaaagc
2941 tgatttttct tgttatagaa aaactaatat aaaagcatta tccctaaaaa aaaaaaaaaa
3001 a
//