LOCUS BC028237 2175 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens growth differentiation factor 10, mRNA (cDNA clone
MGC:39897 IMAGE:5245100), complete cds.
ACCESSION BC028237
VERSION BC028237.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2175)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2175)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11641417.
FEATURES Location/Qualifiers
source 1..2175
/db_xref="H-InvDB:HIT000040505"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39897 IMAGE:5245100"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2175
/gene="GDF10"
/gene_synonym="BMP3B"
/db_xref="GeneID:2662"
/db_xref="MIM:601361"
CDS 429..1295
/gene="GDF10"
/gene_synonym="BMP3B"
/codon_start=1
/product="GDF10 protein"
/protein_id="AAH28237.1"
/db_xref="GeneID:2662"
/db_xref="MIM:601361"
/translation="MALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGV
PRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAA
QATGPLQDNELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMA
ASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGA
CEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKV
YPNMSVDTCACR"
misc_feature 984..1292
/gene="GDF10"
/gene_synonym="BMP3B"
/note="TGFB; Region: Transforming growth factor-beta
(TGF-beta) family"
/db_xref="CDD:smart00204"
BASE COUNT 546 a 640 c 572 g 417 t
ORIGIN
1 gggccaggga cgaccctgtc agctgcagcc ccagaggtcc ggggcgcgca gccgggtccc
61 ctcgagggcg cagccggccg ccccgccccg cccctcgaag cagccgggcc gggcgcgcag
121 tgggctacaa actttcgcag cgcgagtccg ccaaggcagc gcgccgactc gggctcggct
181 cggctctgcg ctgctccgga cggctgtgac cgctggccgg gggctcgggc caccggtacc
241 cacggaccgc gcgcccgggt gcctgctccg ctaagcccct cgccccgcgc ggacctcggt
301 atccagcgcc ctgctgcccg ggctctcccc gcgcgcccta ctgccgcgag gtcagtccgc
361 agcctccggt gcgccagcgc tcgccttcct cctcctggac ttcgaccctt tgccgccctc
421 accacgccat ggccctggcg cccccaccgc gcggcctgtg gcaggccaag gacatctccc
481 ccatcgtcaa ggcggcccgc cgggatggcg agctgctcct ctccgcccag ctggattctg
541 aggagaggga cccgggggtg ccccggccca gcccctatgc gccctacatc ctagtctatg
601 ccaacgatct ggccatctcg gagcccaaca gcgtggcagt gacgctgcag agatacgacc
661 ccttccctgc cggagacccc gagccccgcg cagcccccaa caactcagcg gacccccgcg
721 tgcgccgagc cgcgcaggcc actgggcccc tccaggacaa cgagctgccg gggctggatg
781 agaggccgcc gcgcgcccac gcacagcact tccacaagca ccagctgtgg cccagcccct
841 tccgggcgct gaaaccccgg ccagggcgca aagaccgcag gaagaagggc caggaggtgt
901 tcatggccgc ctcgcaggtg ctggactttg acgagaagac gatgcagaaa gcccggagga
961 agcagtggga tgagccgagg gtgtgctccc ggaggtacct gaaggtggac ttcgcagaca
1021 tcggctggaa tgaatggata atctcaccga aatcttttga tgcctactac tgcgcgggag
1081 catgtgagtt ccccatgcct aagatcgttc gtccatccaa ccatgccacc atccagagca
1141 ttgtcagggc tgtgggcatc atccctggca tcccagagcc ctgctgtgtt cccgataaga
1201 tgaactccct tggggtcctc ttcctggatg agaatcggaa tgtggttctg aaggtgtacc
1261 ccaacatgtc cgtggacacc tgtgcctgcc ggtgagacca ctccagggtg gaaagaagcc
1321 acgcccagca gagctgcctt ctcggagcct tctgcaacca ggacttgtgg tgcagctgca
1381 gacacagagc acagctcatg ggcaacatca ctggggccca gagagagctg tccgccagtg
1441 catcattagg gggtctttca ttgctagtga ctagcccctt aaatgccagc ctgagtacct
1501 gaaggaatct gggaatttgc cctggcctga aagtggccca tcattcatac ccactgttct
1561 gaaggcttga aaacaaaaca tatccacaac attggcttga tgtgatcatc atctcataac
1621 tgagcaagaa gactatgcaa atcttagggc gctcgctccc tgcacacgga aagaactctg
1681 tttaaatgct cagttcagaa cactttgggc cacatagtga ttttggaaaa caggataatc
1741 gtggtgtaaa tgagtgtttc ctttcaaagt ccactgcaga gcttttatcc atatggtatg
1801 cacatgtagc caatattggt ttctttttct taatatatat attttatttt aaaacaacaa
1861 aaagggaggg cattgacacc attccccaca gagatagtca tgctgagtgt gggttgttta
1921 aacatgcata ttgaaataac acatatagta acgtgggaat actaaaaaat aaccaagatt
1981 ttatattttt gtaaattata ctttctatac tgtagattgt gtatgttatg tgtttttatg
2041 gaaagctaat aaattaaagg tacagtggta tcttgaaaaa aaaaaaaaaa aaaaaaaaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaaa
//