LOCUS BC028129 3073 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hexokinase 3 (white cell), mRNA (cDNA clone MGC:40018
IMAGE:5211860), complete cds.
ACCESSION BC028129
VERSION BC028129.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3073)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3073)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: f Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504394.
FEATURES Location/Qualifiers
source 1..3073
/db_xref="H-InvDB:HIT000040454"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40018 IMAGE:5211860"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3073
/gene="HK3"
/gene_synonym="HKIII"
/gene_synonym="HXK3"
/db_xref="GeneID:3101"
/db_xref="HGNC:HGNC:4925"
/db_xref="MIM:142570"
CDS 93..2864
/gene="HK3"
/gene_synonym="HKIII"
/gene_synonym="HXK3"
/codon_start=1
/product="hexokinase 3 (white cell)"
/protein_id="AAH28129.1"
/db_xref="GeneID:3101"
/db_xref="HGNC:HGNC:4925"
/db_xref="MIM:142570"
/translation="MDSIGSSGLRQGEETLSCSEEGLPGPSDSSELVQECLQQFKVTR
AQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGDFVVLELGATGAS
LRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVNKQG
LQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIRRQGAYNIDVVA
VVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVSVEWGS
FSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLARCGVLFG
GCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHVCAAVC
TRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLLAPE
CDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKAM
AKGLRGEASSLRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTGVQITSEIY
SIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLN
WTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGL
IVGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGDDGSLAMLSTRFDASVDQASI
NPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIES
DSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRG
LEELAVSVGVDGTLYKLHPRFSSLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVA
CRLAQLTRV"
BASE COUNT 544 a 874 c 1013 g 642 t
ORIGIN
1 gggtgcctca tattgccaga caagagctca gacctgagga gagtgactag cttctctgtg
61 tcccaggtgg ccaccttcca ctgtggaagc tcatggactc cattgggtct tcagggttgc
121 ggcaggggga agaaaccctg agttgctctg aggagggctt gcccgggccc tcagacagct
181 cagagctggt gcaggagtgc ctgcagcagt tcaaggtgac aagggcacag ctacagcaga
241 tccaagccag cctcttgggt tccatggagc aggcgctgag gggacaggcc agccctgccc
301 ctgcggtccg gatgctgcct acatacgtgg ggtccacccc acatggcact gagcaaggag
361 acttcgtggt gctggagctg ggggccacag gggcctcact gcgtgttttg tgggtgactc
421 taactggcat tgaggggcat agggtggagc ccagaagcca ggagtttgtg atcccccaag
481 aggtgatgct gggtgctggc cagcagctct ttgactttgc tgcccactgc ctgtctgagt
541 tcctggatgc gcagcctgtg aacaaacagg gtctgcagct tggcttcagc ttctctttcc
601 cttgtcacca gacgggcttg gacaggagca ccctcatttc ctggaccaaa ggttttaggt
661 gcagtggtgt ggaaggccag gatgtggtcc agctgctgag agatgccatt cggaggcagg
721 gggcctacaa catcgacgtg gttgctgtgg tgaacgacac agtgggcacc atgatgggct
781 gtgagccggg ggtcaggccg tgtgaggttg ggctagttgt agacacgggc accaacgcgt
841 gttacatgga ggaggcacgg catgtggcag tgctggacga agaccggggc cgcgtctgcg
901 tcagcgtcga gtggggctcc ttcagcgatg atggggcgct gggaccagtg ctgaccacct
961 tcgaccatac cctggaccat gagtccctga atcctggtgc tcagaggttt gagaagatga
1021 tcggaggcct gtacctgggt gagctggtgc ggctggtgct ggctcacttg gcccggtgtg
1081 gggtcctctt tggtggctgc acctcccctg ccctgctgag ccaaggcagc atcctcctgg
1141 aacacgtggc tgagatggag gacccctcta ctggggcagc ccgtgtccat gctatcctgc
1201 aggacttggg cctgagccct ggggcttcgg atgttgagct tgtgcagcac gtctgtgcgg
1261 ccgtgtgcac gcgggctgcc cagctctgtg ctgccgccct ggccgctgtt ctctcctgcc
1321 tccagcacag ccgggagcaa caaacactcc aggttgctgt ggccaccgga ggccgagtgt
1381 gtgagcggca ccccaggttc tgcagcgtcc tgcaggggac agtgatgctc ctggccccgg
1441 aatgcgatgt ctccttaatc ccctctgtgg atggtggtgg ccggggagtg gcgatggtga
1501 ctgctgtggc tgcccgtctg gctgcccacc ggcgcctgct ggaggagacc ctggccccat
1561 tccggttgaa ccatgatcaa ctggctgcgg ttcaggcaca gatgcggaag gccatggcca
1621 aggggctccg aggggaggcc tcctcccttc gcatgctgcc cactttcgtc cgggccaccc
1681 ctgatggcag cgagcgaggg gatttcctgg ccctggacct cgggggcacg aacttccgtg
1741 tcctcctggt acgtgtgacc acaggcgtgc agatcaccag cgagatctac tccattcccg
1801 agactgtggc ccagggttct gggcagcagc tctttgacca catcgtggac tgcatcgtgg
1861 acttccagca gaagcagggc ctgagcgggc agagcctccc actgggtttt accttctcct
1921 tcccatgtag gcagcttggc ctagaccagg gcatcctcct gaactggacc aagggtttca
1981 aggcatcaga ctgcgagggc caagatgtcg tgagtctgtt gcgggaagcc atcactcgca
2041 gacaggcagt ggagctgaat gtggttgcca ttgtcaatga cacggtgggg accatgatgt
2101 cctgtggcta tgaggacccc cgttgcgaga taggcctcat tgtcggaacc ggcaccaatg
2161 cctgctacat ggaggagctc cggaatgtgg cgggcgtgcc tggggactca ggccgcatgt
2221 gcatcaacat ggagtggggc gcctttgggg acgatggctc tctggccatg ctcagcaccc
2281 gctttgatgc aagtgtggac caggcgtcca tcaaccccgg caagcagagg tttgaaaaga
2341 tgatcagcgg catgtacctg ggggagatcg tccgccacat ccttttacat ttaaccagcc
2401 ttggcgttct cttccggggc cagcagatcc agcgccttca gaccagggac atcttcaaga
2461 ccaagttcct ctctgagatc gaaagtgaca gcctggccct gcggcaggtc cgagccatcc
2521 tagaggatct ggggctaccc ctgacctcag atgacgccct gatggtgcta gaggtgtgcc
2581 aggctgtgtc ccagagggct gcccagctct gtggggcggg tgtagctgcc gtggtggaga
2641 agatccggga gaaccggggc ctggaagagc tggcagtgtc tgtgggggtg gatggaacgc
2701 tctacaagct gcacccgcgc ttctccagcc tggtggcggc cacagtgcgg gagctggccc
2761 ctcgctgtgt ggtcacgttc ctgcagtcag aggatgggtc cggcaaaggt gcggccctgg
2821 tcaccgctgt tgcctgccgc cttgcgcagt tgactcgtgt ctgaggaaac ctccaggctg
2881 aggaggtctc cgccgcagcc ttgctggagc cgggtcgggg tctgcctgtt tcccagccag
2941 gcccagccac ccaggactcc tgggacatcc catgtgtgac ccctctgcgg ccatttggcc
3001 ttgctccctg gctttccctg agagaagtag cactcaggtt agcaatatat atatataatt
3061 tatttaaaaa aaa
//