LOCUS BC028024 2756 bp mRNA linear HUM 27-APR-2005
DEFINITION Homo sapiens hyperpolarization activated cyclic nucleotide-gated
potassium channel 3, mRNA (cDNA clone IMAGE:4156701), partial cds.
ACCESSION BC028024
VERSION BC028024.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2756)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2756)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: k Column: 11.
FEATURES Location/Qualifiers
source 1..2756
/db_xref="H-InvDB:HIT000040406"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4156701"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2756
/gene="HCN3"
/gene_synonym="KIAA1535"
/db_xref="GeneID:57657"
CDS <1..1354
/gene="HCN3"
/gene_synonym="KIAA1535"
/codon_start=2
/product="HCN3 protein"
/protein_id="AAH28024.2"
/db_xref="GeneID:57657"
/translation="HASAMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVE
QYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHM
PLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDTR
LTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMD
RLLRIGKKNSILQRKRSEPSPGSSGGIMEQHLVQHDRDMARGVRGRAPSTGAQLSGKP
VLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLV
PVRAGPWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQ
PSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLSANM
"
BASE COUNT 554 a 841 c 707 g 654 t
ORIGIN
1 ccacgcgtcc gccatgctca gcatgatcgt aggtgccaca tgctacgcca tgttcatcgg
61 ccatgccacg gcactcatcc agtccctgga ctcttcccgg cgtcagtacc aggagaagta
121 caagcaggtg gagcagtaca tgtccttcca caagctgcca gcagacacgc ggcagcgcat
181 ccacgagtac tatgagcacc gctaccaggg caagatgttc gatgaggaaa gcatcctggg
241 cgagctgagc gagccgcttc gcgaggagat cattaacttc acctgtcggg gcctggtggc
301 ccacatgccg ctgtttgccc atgccgaccc cagcttcgtc actgcagttc tcaccaagct
361 gcgctttgag gtcttccagc cgggggatct cgtggtgcgt gagggctccg tggggaggaa
421 gatgtacttc atccagcatg ggctgctcag tgtgctggcc cgcggcgccc gggacacacg
481 cctcaccgat ggatcctact ttggggagat ctgcctgcta actaggggcc ggcgcacagc
541 cagtgttcgg gctgacacct actgccgcct ttactcactc agcgtggacc atttcaatgc
601 tgtgcttgag gagttcccca tgatgcgccg ggcctttgag actgtggcca tggatcggct
661 gctccgcatc ggcaagaaga attccatact gcagcggaag cgctccgagc caagtccagg
721 cagcagtggt ggcatcatgg agcagcactt ggtgcaacat gacagagaca tggctcgggg
781 tgttcggggt cgggccccga gcacaggagc tcagcttagt ggaaagccag tactgtggga
841 gccactggta catgcgcccc ttcaggcagc tgctgtgacc tccaatgtgg ccattgccct
901 gactcatcag cggggccctc tgcccctctc ccctgactct ccagccaccc tccttgctcg
961 ctctgcttgg cgctcagcag gctctccagc ttccccgctg gtgcccgtcc gagctggccc
1021 atgggcatcc acctcccgcc tgcccgcccc acctgcccga accctgcacg ccagcctatc
1081 ccgggcaggg cgctcccagg tctccctgct gggtccccct ccaggaggag gtggacggcg
1141 gctaggacct cggggccgcc cactctcagc ctcccaaccc tctctgcctc agcgggcaac
1201 aggcgatggc tctcctgggc gtaagggatc aggaagtgag cggctgcctc cctcagggct
1261 cctggccaaa cctccaagga cagcccagcc ccccaggcca ccagtgcctg agccagccac
1321 accccggggt ctccagcttt ctgccaacat gtaaaacctt tgagtacatc cagccttagt
1381 tcttggggtg cagtagtatg tacccaaggg cagatgcctc ttggggaagg ccatggggac
1441 ctgaaacatt gccccatgga aatgtcgacc ctgtgcggac attccgcata ctgccatgaa
1501 gacggtctct gtgtcctcag ctcaagaatc ctgtagcttg tcccatcata atccattcac
1561 ccgttcatca tgtgtactga gcagctacca tgttcaaggt aatatgccag gcgctgtatg
1621 tctccactgc caagtagaag tgactcaaaa ccctctgaca aggatattcc cttggctatg
1681 gtcctgccag gtgcaggccc aggcccatga ccccaccttt actaagcaca agtacttgcc
1741 actgccatca ctgccaagta actagatgtc tctgtttccc tgccaatgat cctgcaggtt
1801 ctgcccggtc tggttatctt cctgttcctg tagcatagcc aggcactgcc aatcatctgt
1861 gcccccattg ctgtcagcag atgtcttggg tcctgagtgt gggtatccac ttttacccgc
1921 tcactgccac ctgtggacac tctgtgtcta ccctctgagt gggaacatac ttctaagttc
1981 cctgcagtct ctgtcctgtg gtagaccatc tttttgtaaa ctgcgagctt cctcttccct
2041 gtaccctctg ccccagtcgt gaccccctaa aagttaaggg gtagttggca cctccttatt
2101 aatatgccag cctagatccc ccccggtgga ggggcaaatg gctgaatcct tgtgtgatat
2161 ttttttcttc gcttgtttat ttattcattt atttaattgt atttattcat ttactaactt
2221 tatgtgttac caattaattt tgtttaccca ttcctttatc catccctccc ctccttttca
2281 ggtaaggaga caggaggagt aggaggaggc agggcctctc catgccagcc tctgtggtcc
2341 ttgcccaaac ccatcagcgc aatacttgaa ccttctccca ggtaggggca ggaggagcca
2401 catgagagag ggagaaggac cgtgtttacc tttagagttt tgttttgttt tttccttctg
2461 agtttgctgt tggtgcagga ataagggaaa ggcccaaggt atccaagcct ggggaagggc
2521 aggccagcca gcacctctgc cttctcaggg acaagagtag tcctttacca ccctcactct
2581 gcctgtcccc tctcctactc tacagcatta aagactgtgg gaccaggacc ctaagtctcc
2641 tttccttctg ggtggggagt tctggggttc ttggtgtgtg ggagaagttt tataattgct
2701 tccaaacagc tgggtttaaa tataaaatag acacactcaa aaaaaaaaaa aaaaaa
//