LOCUS BC027984 2208 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glycogen synthase kinase 3 alpha, mRNA (cDNA clone
MGC:40141 IMAGE:3903896), complete cds.
ACCESSION BC027984
VERSION BC027984.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2208)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2208)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: a Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 49574531.
FEATURES Location/Qualifiers
source 1..2208
/db_xref="H-InvDB:HIT000040392"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40141 IMAGE:3903896"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2208
/gene="GSK3A"
/db_xref="GeneID:2931"
/db_xref="HGNC:HGNC:4616"
/db_xref="MIM:606784"
CDS 139..1590
/gene="GSK3A"
/codon_start=1
/product="glycogen synthase kinase 3 alpha"
/protein_id="AAH27984.1"
/db_xref="GeneID:2931"
/db_xref="HGNC:HGNC:4616"
/db_xref="MIM:606784"
/translation="MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPG
GTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTT
VVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRE
LQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPI
LYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPN
VSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIK
VLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRL
SPLEACAHSFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAG
TTTLTPSSQALTETPTSSDWQSTDATPTLTNSS"
BASE COUNT 446 a 724 c 624 g 414 t
ORIGIN
1 ccacgcgtcc gagccggagc ccaagccaga gcggcgcggc ctggaagagg ccagggcccg
61 ggggaggcgg cggcagcggc ggcggctggg gcagcccggg cagcccgagc cccgcagcct
121 gggcctgtgc tcggcgccat gagcggcggc gggccttcgg gaggcggccc tgggggctcg
181 ggcagggcgc ggactagctc gttcgcggag cccggcggcg gaggcggagg aggcggcggc
241 ggccccggag gctcggcctc cggcccaggc ggcaccggcg gcggaaaggc atctgtcggg
301 gccatgggtg ggggcgtcgg ggcctcgagc tccgggggtg gacccggcgg cagcggcgga
361 ggaggcagcg gaggccccgg cgcaggcact agcttcccgc cgcccggggt gaagctgggc
421 cgtgacagcg ggaaggtgac cacagtcgta gccactctag gccaaggccc agagcgctcc
481 caagaagtgg cttacacgga catcaaagtg attggcaatg gctcatttgg ggtcgtgtac
541 caggcacggc tggcagagac cagggaacta gtcgccatca agaaggttct ccaggacaag
601 aggttcaaga accgagagct gcagatcatg cgtaagctgg accactgcaa tattgtgagg
661 ctgagatact ttttctactc cagtggcgag aagaaagacg agctttacct aaatctggtg
721 ctggaatatg tgcccgagac agtgtaccgg gtggcccgcc acttcaccaa ggccaagttg
781 accatcccta tcctctatgt caaggtgtac atgtaccagc tcttccgcag cttggcctac
841 atccactccc agggcgtgtg tcaccgcgac atcaagcccc agaacctgct ggtggaccct
901 gacactgctg tcctcaagct ctgcgatttt ggcagtgcaa agcagttggt ccgaggggag
961 cccaatgtct cctacatctg ttctcgctac taccgggccc cagagctcat ctttggagcc
1021 actgattaca cctcatccat cgatgtttgg tcagctggct gtgtactggc agagctcctc
1081 ttgggccagc ccatcttccc tggggacagt ggggtggacc agctggtgga gatcatcaag
1141 gtgctgggaa caccaacccg ggaacaaatc cgagagatga accccaacta cacggagttc
1201 aagttccctc agattaaagc tcacccctgg acaaaggtgt tcaaatctcg aacgccgcca
1261 gaggccatcg cgctctgctc tagcctgctg gagtacaccc catcctcaag gctctcccca
1321 ctagaggcct gtgcgcacag cttctttgat gaactgcgat gtctgggaac ccagctgcct
1381 aacaaccgcc cacttccccc tctcttcaac ttcagtgctg gtgaactctc catccaaccg
1441 tctctcaacg ccattctcat ccctcctcac ttgaggtccc cagcgggcac taccaccctc
1501 accccgtcct cacaagcttt aactgagact ccgaccagct cagactggca gtcgaccgat
1561 gccacaccta ccctcactaa ctcctcctga gggccccacc aagcaccctt ccacttccat
1621 ctgggagccc caagaggggc tgggaagggg ggccatagcc catcaagctc ctgccctggc
1681 tgggccccta gactagaggg cagaggtaaa tgagtccctg tccccacctc cagtccctcc
1741 ctcaccagcc tcacccctgt ggtgggcttt ttaagaggat tttaactggt tgtggggagg
1801 gaagagaagg acagggtgtt ggggggatga ggacctccta cccccttggc cccctcccct
1861 cccccagacc tccacctcct ccagaccccc tcccctcctg tgtcccttgt aaatagaacc
1921 agcccagccc gtctcctctt cccttccctg gcccccgggt gtaaatagat tgttataatt
1981 tttttcttaa agaaaacgtc gattcgcacc gtccaacctg gccccgcccc tcctacagct
2041 gtaactcccc tcctgtcctc tgcccccaag gtctactccc tcctcacccc accctggagg
2101 gccaggggag tggagagagc tcctgatgtc ttagtttcca cagtaaggtt tgcctgtgta
2161 cagacctccg ttcaataaat tattggcatg aaaaaaaaaa aaaaaaaa
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