LOCUS BC027942 3748 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens T-box 5, mRNA (cDNA clone MGC:35581 IMAGE:5204163),
complete cds.
ACCESSION BC027942
VERSION BC027942.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3748)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3748)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: f Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18201895.
FEATURES Location/Qualifiers
source 1..3748
/db_xref="H-InvDB:HIT000040369"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:35581 IMAGE:5204163"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3748
/gene="TBX5"
/db_xref="GeneID:6910"
/db_xref="HGNC:HGNC:11604"
/db_xref="MIM:601620"
CDS 496..2052
/gene="TBX5"
/codon_start=1
/product="T-box 5"
/protein_id="AAH27942.1"
/db_xref="GeneID:6910"
/db_xref="HGNC:HGNC:11604"
/db_xref="MIM:601620"
/translation="MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQA
AFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYIL
LMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKL
TNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQ
NHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSS
ESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT
DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPS
LEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQL
GEGMFQHQTSVAHQPVVRQCGPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGV
GMVPEWSDNS"
BASE COUNT 1072 a 961 c 834 g 881 t
ORIGIN
1 ttcagagaga gagagagagg gagagagagt gagagagact gactcttacc tcgaatccgg
61 gaactttaat cctgaaagct gcgctcagaa aggacttcga ccattcactg ggcttccaac
121 tttccctccc tgggggtgta aaggaggagc ggggcactga gattatatgg ttgccggtgc
181 tcttggaggc tattttgtgt tctttggcgc ttgccaactg ggaagtattt agggagagca
241 agcgcacagc agaggaggtg tgtgttggag gtgggcagtc gccgcggagg ctccagcggt
301 aggtgcgccc tagtaggcag cagtagccgc tattctgggt aagcagtaaa ccccgcataa
361 accccggagc caccatgcct gctcccccgc ctcaccgccg gcttccctgc taggagcagc
421 agaggatgtg gtgaatgcac cggcttcacc gaacgagagc agaaccttgc gcgggcacag
481 ggccctgggc gcaccatggc cgacgcagac gagggctttg gcctggcgca cacgcctctg
541 gagcctgacg caaaagacct gccctgcgat tcgaaacccg agagcgcgct cggggccccc
601 agcaagtccc cgtcgtcccc gcaggccgcc ttcacccagc agggcatgga gggaatcaaa
661 gtgtttctcc atgaaagaga actgtggcta aaattccacg aagtgggcac ggaaatgatc
721 ataaccaagg ctggaaggcg gatgtttccc agttacaaag tgaaggtgac gggccttaat
781 cccaaaacga agtacattct tctcatggac attgtacctg ccgacgatca cagatacaaa
841 ttcgcagata ataaatggtc tgtgacgggc aaagctgagc ccgccatgcc tggccgcctg
901 tacgtgcacc cagactcccc cgccaccggg gcgcattgga tgaggcagct cgtctccttc
961 cagaaactca agctcaccaa caaccacctg gacccatttg ggcatattat tctaaattcc
1021 atgcacaaat accagcctag attacacatc gtgaaagcgg atgaaaataa tggatttggc
1081 tcaaaaaata cagcgttctg cactcacgtc tttcctgaga ctgcgtttat agcagtgact
1141 tcctaccaga accacaagat cacgcaatta aagattgaga ataatccctt tgccaaagga
1201 tttcggggca gtgatgacat ggagctgcac agaatgtcaa gaatgcaaag taaagaatat
1261 cccgtggtcc ccaggagcac cgtgaggcaa aaagtggcct ccaaccacag tcctttcagc
1321 agcgagtctc gagctctctc cacctcatcc aatttggggt cccaatacca gtgtgagaat
1381 ggtgtttccg gcccctccca ggacctcctg cctccaccca acccataccc actgccccag
1441 gagcatagcc aaatttacca ttgtaccaag aggaaagagg aagaatgttc caccacagac
1501 catccctata agaagcccta catggagaca tcacccagtg aagaagattc cttctaccgc
1561 tctagctatc cacagcagca gggcctgggt gcctcctaca ggacagagtc ggcacagcgg
1621 caagcttgca tgtatgccag ctctgcgccc cccagcgagc ctgtgcccag cctagaggac
1681 atcagctgca acacgtggcc aagcatgcct tcctacagca gctgcaccgt caccaccgtg
1741 cagcccatgg acaggctacc ctaccagcac ttctccgctc acttcacctc ggggcccctg
1801 gtccctcggc tggctggcat ggccaaccat ggctccccac agctgggaga gggaatgttc
1861 cagcaccaga cctccgtggc ccaccagcct gtggtcaggc agtgtgggcc tcagactggc
1921 ctgcagtccc ctggcaccct tcagccccct gagttcctct actctcatgg cgtgccaagg
1981 actctatccc ctcatcagta ccactctgtg cacggagttg gcatggtgcc agagtggagc
2041 gacaatagct aaagtgaggc ctgcttcaca acagacattt cctagagaaa gagagagaga
2101 gaggagaaag agagagaagg agagagacag tagccaagag aaccccacag acaagatttt
2161 tcatttcacc caatgttcac atctgcactc aaggtcgctg gatgctgatc taatcagtag
2221 cttgaaacca caattttaaa aatgtgactt tcttgttttg tctcaaaact taaaaaaaca
2281 aacacaaaaa gatgagtccc accccccact accaccacac ccatcaacca gccacattca
2341 cgctactccc cagatctctt cccccattcc ttcttttggg ctctagaaag tcttgcctca
2401 ttgagtgttt ttccctagtg cgtagttgga gtctgtccct gtcttggtgt taatgttgac
2461 attgttatat aataaatgat aatatatttt tttctttcaa ttttcttaat gggacccagt
2521 cccttatttg gggggaggtc tgaggcaagt atatttcaaa atatgtactt gcgggattcc
2581 cttcaagtaa accatccctg aaacctaaat tcacgtttcc ccttgactaa gaaaagcacc
2641 tacctctgcc atgtgatgtt tctgaaaagc ctctgtatgt ccccatttgc tttggttttg
2701 tcctgccttc tccaatatca cgtgctcagt tttgcctcta cttacccatg gagtcaggat
2761 aacactgacg ctccctggca tcctatctta ctcagcccta ccatcttgcc agctctgtct
2821 ttccagctgt ctgtcgctaa aacgtggcct atagcttccc ttccggaaag cttgctttga
2881 aaaacttaaa aagcccccgt ttacatgtag gcaggactgt gataacagtg caagctctgt
2941 gttgacaaga gttgtggaca aaaagccaaa ataaatattc ttcctgatta aaaaaatttt
3001 ttttgaaaaa aacaaggcca gccccaacct tccaaacctc catcaccaac aacccaaact
3061 ggatgtcaag caaaatgcac aattcctaca gaagaggcaa gacacagtca ccaatgatat
3121 ctcgccaaag aaaccacgcc cacaccaatg ccgacacaaa actgtgttta ctgaaagccg
3181 aaaacagtat taaaaaaagt gtgtaagtaa agtgttatgg tagggttctt cagatgtaat
3241 attttactgg tactatttat ttataaatag gaattctaat taagtaataa catgaaatga
3301 aacccagcat aggagctggc caagagcttt taattttatt gatactcaaa accaagtttg
3361 tgtttttttg tttttttttg tttttttcct ctttcgaatg tgctttgctt tttttgatta
3421 aaaagaattt ttttttcctt ttttataaac agaccctaat aaagagaaca gggtaagatg
3481 tgaggctgag tgtgtttaag tacgtgagag agtgtgagtg tgtttgtaag tgagtgtccc
3541 tatgcgatta tgtctcttta cgttgctaag gggggagggt gaggattaag tactcgtgcc
3601 ttatatttgt gtgccaatta atgcctaata aataccatgt gcttaaacaa gtaaaaaaaa
3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3721 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//