LOCUS BC027930 1951 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens death effector domain containing 2, mRNA (cDNA clone
MGC:35529 IMAGE:5199772), complete cds.
ACCESSION BC027930
VERSION BC027930.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1951)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1951)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: b Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31377621.
FEATURES Location/Qualifiers
source 1..1951
/db_xref="H-InvDB:HIT000040360"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:35529 IMAGE:5199772"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1951
/gene="DEDD2"
/gene_synonym="FLAME-3"
/db_xref="GeneID:162989"
/db_xref="HGNC:HGNC:24450"
CDS 69..1049
/gene="DEDD2"
/gene_synonym="FLAME-3"
/codon_start=1
/product="death effector domain containing 2"
/protein_id="AAH27930.1"
/db_xref="GeneID:162989"
/db_xref="HGNC:HGNC:24450"
/translation="MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELEL
LAFLLDEAPGAAGGLARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHL
ARKRRRPVSPERYSYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRS
RGRPSGGARRRRRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVA
SRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALR
GVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS"
BASE COUNT 402 a 602 c 588 g 359 t
ORIGIN
1 cgcccaggag tcatcggacg ccagaatctg gccgggttct gagcttgttc cgcctccctc
61 ccccgggaat ggcgctatcc gggtcgaccc cggccccgtg ctgggaggag gatgagtgcc
121 tggactacta cgggatgctg tcgcttcacc gtatgttcga ggtggtgggc gggcaactga
181 ccgagtgcga gctggagctc ctggcctttc tgctggatga ggctcctggc gccgccggag
241 gcttagcccg ggcccgcagc ggcctagagc tcctgctgga gctggagcgc cgcgggcagt
301 gcgacgagag caacctgcgg ctgctggggc aactcctgcg cgtgctggcc cgccacgacc
361 tgctgccgca cctggcgcgc aagcggcgcc ggccagtgtc tccagaacgc tatagctatg
421 gcacctccag ctcttcaaag aggacagagg gtagctgccg tcgccgtcgg cagtcaagca
481 gttctgcaaa ttctcagcag ggtcagtggg agacaggctc ccccccaacc aagcggcagc
541 ggcggagtcg gggccggccc agtggtggtg ccagacggcg gcggagaggg gccccagccg
601 caccccagca gcagtcagag cccgccagac cttcctctga aggcaaagtg acctgtgaca
661 tccggctccg ggttcgagca gagtactgcg agcatgggcc agccttggag cagggcgtgg
721 catcccggcg gccccaggcg ctggcgcggc agctggacgt gtttgggcag gccaccgcag
781 tgctgcgctc aagggacctg ggctccgtgg tttgtgacat caagttctca gagctctcct
841 atctggacgc cttctggggc gactacctga gtggtgccct gctgcaggcc ctgcggggcg
901 tgttcctgac tgaggccctg cgagaggctg tgggccggga ggctgttcgc ctgctggtca
961 gtgtggatga ggctgactat gaggctggcc ggcgccgcct gttgctgatg gaggaggaag
1021 gggggcggcg cccgacagag gcctcctgat ccaggactgg caggattgat cccacctcca
1081 agtctccggg ccaccttctc ctgggaggac gaccatctct acccctagag gactgtcact
1141 ctagcatctt tgaggactgc gacaggaccg ggacagcagg ccccttgaca gcccctccca
1201 caggatgtgg gctctgaggc ctaaaccatt tccagctgag tttccttccc agactcctcc
1261 tacccccagg tgtgccccct tagcctccgg aggcgggggc tgggcctgta tctcagaagg
1321 gaggggcaca gctacacact caccaaaggc ccccctgcac attgtatctc tgatcttggg
1381 ctgtctgcac tgtcacaggt gcacacactc gctcatgctc acactgcccc tgctgagatc
1441 ttccctgggc ctctgccctg gcctgcttcc cagcacacac ttctttggcc taagggcttc
1501 tctctcagga cctctaattt gaccacaacc aacctgggct tcagccacat cagtgggcac
1561 tggagctggg gtgcacatgg ggcctgctca ccttgcccac acatctccag ccagccaggg
1621 ccctgcccag cttcaattta cagacctgac tctcctcacc ttcccccctg ctgtccagag
1681 ctgaacatag acttgcactt ggatgtcacc tggagtgtca catgggagtg ttatggcagc
1741 atcataccaa ggcctactgt tgcacatggg gccaaaacca gtaaacagcc accttcttgg
1801 aaagggaatg caaaggcttt gggggtgatg gaaaagacct tttacaaatg ataccaatta
1861 aactgccctg gaaagggcat aggtgggaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1921 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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