LOCUS       BC027917                 556 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens defensin, alpha 3, neutrophil-specific, mRNA (cDNA
            clone MGC:34189 IMAGE:5226993), complete cds.
ACCESSION   BC027917
VERSION     BC027917.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-APR-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Life Technologies, Inc.
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 49 Row: n Column: 3
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 12621915.
FEATURES             Location/Qualifiers
     source          1..556
                     /db_xref="H-InvDB:HIT000040353"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:34189 IMAGE:5226993"
                     /tissue_type="Pancreas, Spleen, adult pooled"
                     /clone_lib="NIH_MGC_120"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     gene            1..556
                     /gene="DEFA3"
                     /gene_synonym="HNP-3"
                     /gene_synonym="HNP3"
                     /gene_synonym="HP-3"
                     /db_xref="GeneID:1668"
                     /db_xref="HGNC:HGNC:2762"
                     /db_xref="MIM:604522"
     CDS             73..357
                     /gene="DEFA3"
                     /gene_synonym="HNP-3"
                     /gene_synonym="HNP3"
                     /gene_synonym="HP-3"
                     /codon_start=1
                     /product="defensin, alpha 3, neutrophil-specific"
                     /protein_id="AAH27917.1"
                     /db_xref="GeneID:1668"
                     /db_xref="HGNC:HGNC:2762"
                     /db_xref="MIM:604522"
                     /translation="MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVV
                     VSLAWDESLAPKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC"
BASE COUNT          194 a          131 c          120 g          111 t
ORIGIN      
        1 gacctgggac agaggactgc tgtctgccct ctctggtcac cctgcctagc tagaggatct
       61 gtgaccccag ccatgaggac cctcgccatc cttgctgcca ttctcctggt ggccctgcag
      121 gcccaggctg agccactcca ggcaagagct gatgaggttg ctgcagcccc ggagcagatt
      181 gcagcggaca tcccagaagt ggttgtttcc cttgcatggg acgaaagctt ggctccaaag
      241 catccaggct caaggaaaaa catggactgc tattgcagaa taccagcgtg cattgcagga
      301 gaacgtcgct atggaacctg catctaccag ggaagactct gggcattctg ctgctgagct
      361 tgcagaaaaa gaaaaatgag ctcaaaattt gctttgagag ctacagggaa ttgctattac
      421 tcctgtacct tctgctcaat ttcctttcct catctcaaat aaatgccttg ttacaagaaa
      481 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      541 aaaaaaaaaa aaaaaa
//