LOCUS BC027870 1632 bp mRNA linear HUM 24-FEB-2004
DEFINITION Homo sapiens PDZ and LIM domain 3, mRNA (cDNA clone MGC:36764
IMAGE:5205215), complete cds.
ACCESSION BC027870
VERSION BC027870.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1632)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1632)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: g Column: 12.
FEATURES Location/Qualifiers
source 1..1632
/db_xref="H-InvDB:HIT000040327"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:36764 IMAGE:5205215"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1632
/gene="PDLIM3"
/gene_synonym="ALP"
/db_xref="GeneID:27295"
/db_xref="MIM:605889"
CDS 52..1002
/gene="PDLIM3"
/gene_synonym="ALP"
/codon_start=1
/product="PDLIM3 protein"
/protein_id="AAH27870.1"
/db_xref="GeneID:27295"
/db_xref="MIM:605889"
/translation="MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLC
PGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFK
INLESEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALH
GQLRGLIPSSPQNEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDD
RPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN
LNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA"
misc_feature 52..297
/gene="PDLIM3"
/gene_synonym="ALP"
/note="PDZ; Region: PDZ domain, PSD95(post synaptic
density protein) DlgA (Drosophila disc large tumor
suppressor) ZO1, a mammalian tight junction protein
domain"
/db_xref="CDD:cd00136"
misc_feature 460..537
/gene="PDLIM3"
/gene_synonym="ALP"
/note="ZM; Region: ZASP-like motif"
/db_xref="CDD:smart00735"
misc_feature 787..939
/gene="PDLIM3"
/gene_synonym="ALP"
/note="LIM; Region: LIM domain. This family represents two
copies of the LIM structural domain"
/db_xref="CDD:pfam00412"
BASE COUNT 513 a 378 c 380 g 361 t
ORIGIN
1 ggctgccctg cgcggggaca ctcagagccc ggtgggcggg aggaaggcgg catgccccag
61 acggtgatcc tcccgggccc tgcgccctgg ggcttcaggc tctcaggggg catagacttc
121 aaccagcctt tggtcatcac caggattaca ccaggaagca aggcggcagc tgccaacctg
181 tgtcctggag atgtcatcct ggctattgac ggctttggga cagagtccat gactcatgct
241 gatgcgcagg acaggattaa agcagcagct caccagctgt gtctcaaaat tgacagggga
301 gaaactcact tatggtctcc acaagtatct gaagatggga aagcccatcc tttcaaaatc
361 aacttagaat cagaaccaca ggaattcaaa cccattggta ccgcgcacaa cagaagggcc
421 cagccttttg ttgcagctgc aaacattgat gacaaaagac aggtagtgag cgcttcctat
481 aactcgccaa ttgggctcta ttcaactagc aatatacaag atgcgcttca cggacagctg
541 cggggtctca ttcctagctc acctcaaaac gagcccacag cctcggtgcc ccccgagtcg
601 gacgtgtacc ggatgctcca cgacaatcgg aatgagccca cacagcctcg ccagtcgggc
661 tccttcagag tgctccaggg aatggtggac gatggctctg atgaccgtcc ggctggaacg
721 cggagtgtga gagctccggt gacgaaagtc catggcggtt caggcggggc acagaggatg
781 ccgctctgtg acaaatgtgg gagtggcata gttggtgctg tggtgaaggc gcgggataag
841 taccggcacc ctgagtgctt cgtgtgtgcc gactgcaacc tcaacctcaa gcaaaagggc
901 tactttttca tagaagggga gctgtactgc gaaacccacg caagagcccg cacaaagccc
961 ccagagggct atgacacggt cactctgtat cccaaagctt aagtctctgc aggcgtggca
1021 cgcacgcacg cacccaccca cgcgcactta cacgagaaga cattcatggc tttgggcaga
1081 aggattgtgc agattgtcaa ctccaaatct aaagtcaagg ctttagacct ttatcctatt
1141 gtttattgag gaaaaggaat gggaggcaaa tgcctgctat gtgaaaaaaa catacactta
1201 gctatgtttt gcaactcttt ttggggctag caataatgat atttaaagca ataatttttt
1261 gtatgtcata ctccacaatt tacatgtata ttacagccat caaacacata aacatcaaga
1321 tatttgaagg actctaattg tctttccttg acaagttgat tttgcaattg tggtaaatag
1381 caaataacaa tcttgtattc taacataatc tgcagttgtc tgtatgtgtt ttaactatta
1441 cagtgcatgt tagggagaaa ttccctgaat ttctttagtt ttgtattcaa acaattatgc
1501 cactcgatgc aacaaacata ataaatacat aaaagattta aaaaaaaaaa aaaaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 aaaaaaaaaa aa
//