LOCUS BC027720 2722 bp mRNA linear HUM 09-JUN-2008 DEFINITION Homo sapiens leucine rich repeat neuronal 4, mRNA (cDNA clone MGC:20770 IMAGE:4588586), complete cds. ACCESSION BC027720 VERSION BC027720.2 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2722) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 2722) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT On Aug 19, 2003 this sequence version replaced BC027720.1. Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: DCTD/DTP cDNA Library Preparation: Rubin Laboratory cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: National Institutes of Health Intramural Sequencing Center (NISC), Gaithersburg, Maryland; Web site: http://www.nisc.nih.gov/ Contact: nisc_mgc@nhgri.nih.gov Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B., Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S., Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P., Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R., Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C., McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W., Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L., Young,A., Zhang,L.-H. and Green,E.D. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAL Plate: 30 Row: l Column: 14 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 34303942. FEATURES Location/Qualifiers source 1..2722 /db_xref="H-InvDB:HIT000040305" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:20770 IMAGE:4588586" /tissue_type="Kidney, renal cell adenocarcinoma" /clone_lib="NIH_MGC_14" /lab_host="DH10B-R" /note="Vector: pOTB7" gene 1..2722 /gene="LRRN4" /gene_synonym="dJ1056H1.1" /gene_synonym="NLRR4" /db_xref="GeneID:164312" /db_xref="HGNC:HGNC:16208" CDS 207..2429 /gene="LRRN4" /gene_synonym="dJ1056H1.1" /gene_synonym="NLRR4" /codon_start=1 /product="leucine rich repeat neuronal 4" /protein_id="AAH27720.1" /db_xref="GeneID:164312" /db_xref="HGNC:HGNC:16208" /translation="MRQTLPLLLLTVLRPSWADPPQEKVPLFRVTQQGPWGSSGSNAT DSPCEGLPAADATALTLANRNLERLPGCLPRTLRSLDASHNLLRALSTSELGHLEQLQ VLTLRHNRIAALRWGPGGPAGLHTLDLSYNQLAALLPCTGPALSSLRALALAGNPLRA LQPRAFACFPALQLLNLSCTALGRGAQGGIAEAAFAGEDGAPLVTLEVLDLSGTFLER VESGWIRDLPKLTSLYLRKMPRLTTLEGDIFKMTPNLQQLDCQDSPALASVATHIFQD TPHLQVLLFQNCNLSSFPPWTLDSSQVLSINLFGNPLTCSCDLSWLLTDAKRTVLSRA ADTMCAPAAGSSGPFSASLSLSQLPGVCQSDQSTTLGASHPPCFNRSTYAQGTTVAPS AAPATRPAGDQQSVSKAPNVGSRTIAAWPHSDAREGTAPSTTNSVAGHSNSSVFPRAA STTRTQHRGEHAPELVLEPDISAASTPLASKLLGPFPTSWDRSISSPQPGQRTHATPQ APNPSLSEGEIPVLLLDDYSEEEEGRKEEVGTPHQDVPCDYHPCKHLQTPCAELQRRW RCRCPGLSGEDTIPDPPRLQGVTETTDTSALVHWCAPNSVVHGYQIRYSAEGWAGNQS VVGVIYATARQHPLYGLSPGTTYRVCVLAANRAGLSQPRSSGWRSPCAAFTTKPSFAL LLSGLCAASGLLLASTVVLSACLCRRGQTLGLQRCDTHLVAYKNPAFDDYPLGLQTVS " BASE COUNT 544 a 949 c 773 g 456 t ORIGIN 1 gagcaatggg aaagactgga gtatctcagt ccctctcagt ggatgggggt tgtgggagag 61 aggcagctgg gagacaggcc tccctctgga gttcatagct gagttgctgt ccaaatcagt 121 ggtccctaga atctataaaa caaaactgag aacttcagag gtgcatccag agaagccaca 181 ctccaaaagg accacttcca gacgccatgc ggcaaaccct accgctgctg ctgctgacgg 241 tgctgcgccc cagctgggca gaccctcccc aggagaaggt cccgctcttc cgggtcactc 301 agcagggccc ctgggggagc agtggcagca acgccaccga ctcgccctgc gaggggctgc 361 ccgccgcgga tgcgacggcc ttgaccctgg cgaaccgcaa cctggagcgc ctgcccggct 421 gcctaccgcg cacactgcgc agcctcgacg ccagccacaa cctgctgcgc gccctgagca 481 cttccgagct cggccacctg gagcagctgc aggtgctgac cctgcgccac aaccgcatcg 541 ccgcgctgcg ctggggcccg ggtgggccgg cggggctgca caccctggac ctcagctaca 601 accagctggc cgctctgctg ccgtgcaccg ggcccgcgct gagcagcctc cgcgccctgg 661 cgctcgccgg gaatccgctg cgggcgctgc agccccgggc cttcgcctgc ttccccgcgc 721 tgcaactcct caacctctcc tgcaccgcgc tgggtcgcgg agcccagggg ggcatcgccg 781 aggcggcgtt cgctggagag gatggcgcgc ccctggtcac gctcgaagtc ctggatctca 841 gcggcacgtt ccttgaacgg gttgagtcag ggtggatcag agacctgccg aagctcacat 901 ccctctacct gaggaagatg cctcggctga cgaccctgga gggggacatt ttcaagatga 961 cccccaacct gcagcagctg gactgtcagg actccccagc acttgcttct gtcgccacac 1021 acatctttca agatactcca catctacagg tccttctgtt ccagaactgc aacttgagtt 1081 ccttccctcc ttggaccctg gattcctccc aggtcctatc gatcaacctc tttggcaacc 1141 ccctcacttg cagttgtgac ttgtcttggc tcctcacgga tgcaaagaga actgtcctaa 1201 gcagggcagc agacactatg tgcgcgccag ctgcgggatc cagcggcccc ttctcagcct 1261 ccctgtcact ctcccagctg cccggagtgt gccagtccga ccaaagcacc actctcgggg 1321 cttcacaccc accttgcttc aaccgctcca cctacgcaca gggtaccacc gtcgcgccca 1381 gcgcagcccc cgccacccgg cctgcgggag accagcagag tgtctccaag gcccctaacg 1441 tgggctctcg cacgatagct gcatggccgc acagcgatgc acgggagggg actgccccct 1501 ccacgaccaa ctctgtagca ggtcacagca actccagcgt tttccccagg gctgccagca 1561 ccaccaggac ccagcaccga ggagaacatg cccccgagct tgtccttgag cctgatatct 1621 cagctgcctc caccccactg gccagcaagc tcctgggccc cttccctacc tcgtgggacc 1681 gcagcataag ctcgcctcag cccggccaga ggacacacgc cacaccccaa gcccccaacc 1741 cgagtctttc cgagggcgag attccagtct tgctgctgga cgactacagt gaggaggagg 1801 aagggaggaa ggaggaggtg ggaacgcctc accaggacgt cccctgtgat taccatccct 1861 gcaagcacct gcagaccccg tgcgcggagc tgcagaggcg gtggcggtgc cggtgccccg 1921 gcctcagcgg ggaagacacc atcccagacc cgcccaggct gcagggggtg acggagacca 1981 cggacacgtc ggcgctggtc cactggtgtg cccccaactc ggtagtgcat gggtaccaga 2041 tccgctactc tgcggagggc tgggcgggga accagtcggt ggtgggggtc atctacgcca 2101 cggcccggca gcaccctctg tacgggctgt cgccgggcac cacctaccgc gtgtgcgtgc 2161 tggcggccaa cagggcgggc ttgagccagc cacggtcttc gggctggagg agcccgtgcg 2221 ccgccttcac caccaagccc agcttcgcgc tcctgctctc tgggctgtgc gccgccagcg 2281 gcctgttgct cgccagcacc gtggtgctgt ccgcatgtct ctgcaggcgg ggccagacgc 2341 tgggcctgca gcgctgcgac acgcacctgg tggcctacaa aaacccggcc tttgatgatt 2401 acccgctggg gctccagacc gtcagttagc ccagcttctg ggataacgcg tctcatcgaa 2461 ctggatctga gcgcaaaaag gaagacacag acggtcaaaa acgaccccat ccgctcctag 2521 ggtttctaat tcccgtgaag ccagaatgcc ttgagcacac atggaacttg ccacactgag 2581 tgtctgggtc caaggaactg ctgccctccc ttccttctac ttaactctgt tcccagaaac 2641 ctgatggtca atgccagatc gctccccact gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2701 aaaaataaaa aaaaaaaaaa aa //