LOCUS BC027711 4234 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 23,
mRNA (cDNA clone IMAGE:4111514), partial cds.
ACCESSION BC027711
VERSION BC027711.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4234)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4234)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC027711.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: c Column: 17.
FEATURES Location/Qualifiers
source 1..4234
/db_xref="H-InvDB:HIT000091369"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4111514"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..4234
/gene="PTPN23"
/gene_synonym="DKFZP564F0923"
/gene_synonym="HD-PTP"
/gene_synonym="HDPTP"
/gene_synonym="KIAA1471"
/db_xref="GeneID:25930"
/db_xref="MIM:606584"
CDS <1..3965
/gene="PTPN23"
/gene_synonym="DKFZP564F0923"
/gene_synonym="HD-PTP"
/gene_synonym="HDPTP"
/gene_synonym="KIAA1471"
/codon_start=3
/product="PTPN23 protein"
/protein_id="AAH27711.2"
/db_xref="GeneID:25930"
/db_xref="MIM:606584"
/translation="DFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKL
VPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIP
PQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEA
VGQAGAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLD
QVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVT
TDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQK
WNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLL
DRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSA
TPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPA
PAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATT
TVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSS
GIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY
PYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPS
TRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGA
AAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLR
QLQQELEAFRGQLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYD
SNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVML
VSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRS
LVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFAL
LYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGV
PPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASL
PGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLE
LLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRATRPSDDPLSLLDPLWTLNKT
"
misc_feature 2625..3416
/gene="PTPN23"
/gene_synonym="DKFZP564F0923"
/gene_synonym="HD-PTP"
/gene_synonym="HDPTP"
/gene_synonym="KIAA1471"
/note="PTPc; Region: Protein tyrosine phosphatase,
catalytic domain"
/db_xref="CDD:smart00194"
BASE COUNT 832 a 1522 c 1131 g 749 t
ORIGIN
1 acgacttcat ttaccatgag gctgtcccag cattggacac ccttcagcct gtaaaaggag
61 cccccttggt gaagcccttg ccagtgaacc ccacagaccc agctgttaca ggccctgaca
121 tctttgccaa actggtaccc atggctgccc acgaggcctc gtcactgtac agtgaggaga
181 aggccaagct gctccgggag atgatggcca agattgagga caagaatgag gtcctggacc
241 agttcatgga ttcaatgcag ttggatcccg agacggtgga caaccttgat gcctacagcc
301 acatcccacc ccagctcatg gagaagtgcg cggctctcag cgtccggccc gacactgtca
361 ggaaccttgt acagtccatg caagtgctgt caggtgtgtt cacggatgtg gaggcttccc
421 tgaaggacat cagagatctg ttggaggagg atgagctgct agagcagaag tttcaggagg
481 cggtgggcca ggcaggggcc atctccatca cctccaaggc tgagctggca gaggtgaggc
541 gagaatgggc caagtacatg gaagtccatg agaaggcctc cttcaccaac agtgagctgc
601 accgtgccat gaacctgcac gtcggcaacc tgcgcctgct cagcgggccg cttgaccagg
661 tccgggctgc cctgcccaca ccggccctct ccccagagga caaggccgtg ctgcaaaacc
721 taaagcgcat cctggctaag gtgcaggaga tgcgggacca gcgcgtgtcc ctggagcagc
781 agctgcgtga gcttatccag aaagatgaca tcactgcctc gctggtcacc acagaccact
841 cagagatgaa gaagttgttc gaggagcagc tgaaaaagta tgaccagctg aaggtgtacc
901 tggagcagaa cctggccgcc caggaccgtg tcctctgtgc actgacagag gccaacgtgc
961 agtacgcagc cgtgcggcgg gtactcagcg acttggacca aaagtggaac tccacgctgc
1021 agaccctggt ggcctcgtat gaagcctatg aggacctgat gaagaagtcg caggagggca
1081 gggacttcta cgcagatctg gagagcaagg tggctgctct gctggagcgc acgcagtcca
1141 cctgccaggc ccgcgaggct gcccgccagc agctcctgga cagggagctg aagaagaagc
1201 cgccgccacg gcccacagcc ccaaagccgc tgctgccccg cagggaggag agtgaggcag
1261 tggaagcagg agacccccct gaggagctgc gcagcctccc ccctgacatg gtggctggcc
1321 cacgactgcc tgacaccttc ctgggaagtg ccaccccgct ccactttcct cccagcccct
1381 tccccagctc cacaggccca ggaccccact atctctcagg ccccttgccc cctggtacct
1441 actcgggccc cacccagctg atacagccca gggccccagg gccccatgca atgcccgtag
1501 cacctgggcc tgccctctac ccagcccctg cctacacacc ggagctgggc cttgtgcccc
1561 gatcctcccc acagcatggc gtggtgagca gtccctatgt gggggtaggg ccggccccac
1621 cagttgcagg tctcccctcg gccccacctc ctcaattctc aggccccgag ttggccatgg
1681 cggttcggcc agccaccacc acagtagata gcatccaggc gcccatcccc agccacacag
1741 ccccacggcc aaaccccacc cctgctcctc ccccgccctg cttccctgtg cccccaccgc
1801 agccactgcc cacgccttac acctaccctg caggggctaa gcaacccatc ccagcacagc
1861 accacttctc ttctgggatc cccgcaggtt ttccagcccc aaggattggg ccccagcccc
1921 agccccatcc tcagccccat ccttcacaag cgtttgggcc tcagccccca cagcagcccc
1981 ttccactcca gcatccacat ctcttcccac cccaggcccc aggactccta cccccacaat
2041 ccccctaccc ctatgcccct cagcctgggg tcctggggca gccgccaccc cccctacaca
2101 cccagctcta cccaggtccc gctcaagacc ctctgccagc ccactcaggg gctctgcctt
2161 tccccagccc tgggccccct cagcctcccc atcccccact ggcatatggt cctgcccctt
2221 ctaccagacc catgggcccc caggcagccc ctcttaccat tcgagggccc tcgtctgctg
2281 gccagtccac ccctagtccc cacctggtgc cttcacctgc cccatctcca gggcctggtc
2341 cggtaccccc tcgcccccca gcagcagaac cacccccttg cctgcgccga ggcgccgcag
2401 ctgcagacct gctctcctcc agcccggaga gccagcatgg cggcactcag tctcctgggg
2461 gtgggcagcc cctgctgcag cccaccaagg tggatgcagc tgagggtcgt cggccgcagg
2521 ccctgcggct gattgagcgg gacccctatg aacatcctga gaggctgcgg cagttgcagc
2581 aggagctgga ggcctttcgg ggtcagctgg gggatgtggg agctctggac actgtctggc
2641 gagagctgca agatgcgcag gaacatgatg cccgaggccg ttccatcgcc attgcccgct
2701 gctactcact gaagaaccgg caccaggatg tcatgcccta tgacagtaac cgtgtggtgc
2761 tgcgctcagg caaggatgac tacatcaatg ccagctgcgt ggaggggctc tccccatact
2821 gccccccgct agtggcaacc caggccccac tgcctggcac agctgctgac ttctggctca
2881 tggtccatga gcagaaagtg tcagtcattg tcatgctggt ttctgaggct gagatggaga
2941 agcaaaaagt ggcacgctac ttccccaccg agaggggcca gcccatggtg cacggtgccc
3001 tgagcctggc attgagcagc gtccgcagca ccgaaaccca tgtggagcgc gtgctgagcc
3061 tgcagttccg agaccagagc ctcaagcgct ctcttgtgca cctgcacttc cccacttggc
3121 ctgagttagg cctgcccgac agccccagca acttgctgcg cttcatccag gaggtgcacg
3181 cacattacct gcatcagcgg ccgctgcaca cgcccatcat tgtgcactgc agctctggtg
3241 tgggccgcac gggagccttt gcactgctct atgcagctgt gcaggaggtg gaggctggga
3301 acggaatccc tgagctgcct cagctggtgc ggcgcatgcg gcagcagaga aagcacatgc
3361 tgcaggagaa gctgcacctc aggttctgct atgaggcagt ggtgagacac gtggagcagg
3421 tcctgcagcg ccatggtgtg cctcctccat gcaaaccctt ggccagtgca agcatcagcc
3481 agaagaacca ccttcctcag gactcccagg acctggtcct cggtggggat gtgcccatca
3541 gctccatcca ggccaccatt gccaagctca gcattcggcc tcctgggggg ttggagtccc
3601 cggttgccag cttgccaggc cctgcagagc ccccaggcct cccgccagcc agcctcccag
3661 agtctacccc aatcccatct tcctccccac cccccctttc ctccccacta cctgaggctc
3721 cccagcctaa ggaggagccg ccagtgcctg aagcccccag ctcggggccc ccctcctcct
3781 ccctggaatt gctggcctcc ttgaccccag aggccttctc cctggacagc tccctgcggg
3841 gcaaacagcg gatgagcaag cataactttc tgcaggccca taacgggcaa gggctgcggg
3901 ccacccggcc ctctgacgac cccctcagcc ttctggatcc actctggaca ctcaacaaga
3961 cctgaacagg ttttgcctac ctggtcctta cactacatca tcatcatctc atgcccacct
4021 gcccacaccc agcagagctt ctcagtgggc acagtctctt actcccattt ctgctgcctt
4081 tggccctgcc tggcccagcc tgcacccctg tggggtggaa atgtactgca ggctctgggt
4141 caggttctgc tcctttatgg gacccgacat ttttcagctc tttgctattg aaataataaa
4201 ccaccctgtt ctgtgaaaaa aaaaaaaaaa aaaa
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