LOCUS BC025989 4226 bp mRNA linear HUM 17-JUL-2006 DEFINITION Homo sapiens leucyl-tRNA synthetase 2, mitochondrial, mRNA (cDNA clone MGC:26121 IMAGE:4822546), complete cds. ACCESSION BC025989 VERSION BC025989.2 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 4226) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 4226) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (18-MAR-2002) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT On Aug 25, 2003 this sequence version replaced BC025989.1. Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: Miklos Palkovits, M.D., Ph.D. cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki Toshiyuki and Piero Carninci (RIKEN) cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Institute for Systems Biology http://www.systemsbiology.org contact: amadan@systemsbiology.org Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 33 Row: d Column: 7 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 41352689. FEATURES Location/Qualifiers source 1..4226 /db_xref="H-InvDB:HIT000040054" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:26121 IMAGE:4822546" /tissue_type="Testis" /clone_lib="NIH_MGC_97" /lab_host="DH10B" /note="Vector: pBluescriptR" gene 1..4226 /gene="LARS2" /gene_synonym="KIAA0028" /gene_synonym="LEURS" /gene_synonym="MGC26121" /db_xref="GeneID:23395" /db_xref="HGNC:HGNC:17095" /db_xref="MIM:604544" CDS 193..2904 /gene="LARS2" /gene_synonym="KIAA0028" /gene_synonym="LEURS" /gene_synonym="MGC26121" /codon_start=1 /product="leucyl-tRNA synthetase 2, mitochondrial" /protein_id="AAH25989.1" /db_xref="GeneID:23395" /db_xref="HGNC:HGNC:17095" /db_xref="MIM:604544" /translation="MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSAT GKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHV RVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQ LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANE QVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDC VGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMA LVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGL AYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLIS RQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPR CKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVM HLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVP VHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKT DALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVT THFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSE IWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVP QQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD" BASE COUNT 1082 a 1048 c 1138 g 958 t ORIGIN 1 gctgttttga caacatggcg gcgcccatgg tccgtggccc ggcagtgctc gcctaaaggt 61 ggagaacgag gagtagagga gccacaggcc agagcctgtg agcagatcca gacctacaga 121 taaaaaacat tatttaatct atctgggatt tactccggct tatgatttga gggccttctc 181 accttctgaa gaatggcttc tgtttggcag agattgggtt tttatgcctc tcttctgaaa 241 agacagctaa atggtgggcc agatgtcatc aagtgggaaa ggagagtaat tcccggatgt 301 accagaagca tctacagtgc cacgggaaag tggacaaaag agtatacatt gcagacaaga 361 aaggatgttg agaaatggtg gcatcaacga ataaaagaac aggcctccaa aatttcagaa 421 gctgataaat cgaagccaaa attttacgtg ctttccatgt tcccttatcc ttctggtaag 481 ctgcacatgg gccatgtgcg tgtctacacc atcagcgaca ccatagcacg gttccagaag 541 atgagaggga tgcaggtcat caaccccatg ggatgggatg cttttggatt gcctgctgaa 601 aatgccgcag tcgagaggaa tctacatcca caaagttgga cacaaagtaa tattaaacac 661 atgaggaaac agcttgatcg tctgggcctg tgtttcagct gggataggga aataactacg 721 tgtttgccag attactacaa gtggactcag tatctcttta ttaaactgta tgaggctggg 781 ctggcctatc aaaaggaggc cctggttaac tgggacccag tggatcaaac agtgcttgcc 841 aatgagcagg tggatgaaca tggctgttca tggcgttctg gagcaaaggt ggaacagaag 901 tacctcagac aatggtttat taagacaacc gcttatgcaa aggccatgca ggacgcgttg 961 gcagaccttc cagaatggta tggaataaaa ggcatgcaag cccactggat tggggactgt 1021 gtgggctgcc acctggactt cacattaaag gttcatgggc aagccacggg cgaaaagctg 1081 actgcctata cggccacccc tgaagccatt tatggcacct cccacgtggc catctcgccc 1141 agccacagac tcctacatgg gcacagctct ctgaaggaag ccttgaggat ggcccttgtc 1201 cctggcaaag attgcctcac gcctgtaatg gctgtgaaca tgctcaccca gcaggaggtc 1261 cctgtcgtta ttttggccaa agctgacttg gaaggctctc tggattcaaa aataggaatt 1321 cccagtacta gctcagagga caccatctta gcccaaaccc tgggcctggc ctactctgaa 1381 gtcattgaaa ctttgccaga tggcacagag agactgagca gctctgctga gttcacaggt 1441 atgacccggc aggatgcttt tctagccctg actcagaaag cccgggggaa gagagtgggt 1501 ggagacgtga caagtgataa actgaaagac tggctgattt cacggcagcg gtactggggc 1561 acaccaatcc ccattgtcca ctgcccagtc tgtggcccca cacctgtgcc cctggaggac 1621 ttgcctgtga ccctgcccaa catcgcatct ttcactggca agggaggccc cccactggcc 1681 atggcttcag agtgggtgaa ctgctcctgc ccaaggtgca agggagcagc caagagagag 1741 acagacacga tggatacctt tgttgattct gcttggtact acttcagata cactgaccct 1801 cataatccac acagcccttt taacacagca gtggccgatt actggatgcc tgtggatttg 1861 tacattggag ggaaagaaca tgccgtcatg cacttgttct atgcaagatt ctttagtcat 1921 ttttgccatg atcaaaaaat ggttaaacat agggagcctt ttcataagct gctggcccaa 1981 ggccttatca aggggcagac attccgccta ccatctggac agtatctaca gagagaggaa 2041 gtggatctca caggttccgt tcctgttcat gcaaaaacga aagagaagtt agaggtgacg 2101 tgggagaaga tgagtaagtc caaacacaac ggggtggacc cagaggaagt tgtggagcag 2161 tatgggatcg acacgattcg gctctacatc ctttttgctg cccctcctga gaaggatatc 2221 ttgtgggatg tgaaaactga tgctctccct ggggtgctga gatggcaaca acgactgtgg 2281 accttgacaa ctcggtttat tgaggccagg gcttctggga agtctcccca gcctcagctg 2341 ctgagtaaca aggagaaagc cgaggccagg aagctctggg agtacaagaa ctccgtcatc 2401 tctcaggtga ccacccattt cacagaggac ttctcactga attctgcaat ttctcagctg 2461 atgggactca gcaatgccct ctcgcaagcc tctcagagcg tcattctcca cagccccgag 2521 tttgaggatg ctttgtgtgc cctgatggtg atggctgctc cactggcccc tcatgtaacc 2581 tcagagatct gggcaggcct ggcgctggtg ccgaggaagc tctgtgccca ctacacttgg 2641 gatgccagtg tgctgctcca ggcatggcct gctgtggacc cggagttcct gcagcagcct 2701 gaggttgtcc agatggcagt tctgatcaac aataaagctt gtggcaaaat tcctgtgccc 2761 caacaagttg cccgggacca ggacaaagtc cacgaatttg ttcttcaaag cgagctgggt 2821 gtcaggcttt tgcaaggacg aagcatcaag aagtccttcc tttccccgag aactgccctc 2881 atcaacttcc tggtgcaaga ttgacagcca gtaggctgca gctaccacga gggcctctga 2941 ggaacctcct tccaggcctg ggatgagggg gcgatgtctg ctggcccagg ggaagggaaa 3001 agacaaatgt cttgactgtt gacctcggtc ctgtggcaga ctgcagtcaa cagtgtgcct 3061 ctgtagtgtg gcctggtgct ggggtgaagg tgagctgggc aaaggagaaa tatgagctac 3121 tgaggagggg gttggacatc ctgcccctca ccccccaccc acactgcagg tagaggaggc 3181 catctgatcc catgggaagc catcagagac actgctggtg ggagcaggaa ggagcagtgc 3241 ccctcgagca gccaggaagc ctgcggatct gggaaatggc tctgccttag gcgcttctcg 3301 ggaatttgag gccagcctga ggaactgcag gactcaggtg caatgtgcca gccacttgga 3361 actgctaact gagcctccag atggtagtga atggtctctt tgccttcagg ctggatgagg 3421 aagtcattta ggaaatgttc aaataaccaa tatgtggaaa tggacacagg gatcttctga 3481 agttgctttg aatcaaaagg caggcagtgc tggttcctct gcctgtgtcc ccaccactcc 3541 ccagctctgt catgcaggcc tgtcctcccc aaccccagct ggacgtgcct cccaggcctg 3601 ctgtggttct gacacacagg atcccaggca aggcaccact tcctcacatg aatgaggagc 3661 agcaagtcat aaccactccc ttgggtatac aatttgctgt gtagtgaagt ggaaccaggc 3721 tcaggctgct ggtcccaacc tcagagcccc accgcagccc agtagggatg cagcacgccc 3781 cagagggctc atgtgggccc cagatggcaa tgccaccatt gttgatgtga ctccagagcc 3841 agttattagg aagagcaagc tcaccacaga ggagtggaac tgaggccccc cagatgttgc 3901 ctccggtgtc caagccacag cggtctggct gttgggaaga tggccaggaa tggactcata 3961 ccattggcac attaggctaa tcctggtttt atgtgaagtc agcaattaag tgttcccact 4021 agaactgacc taagccactg attaatattt aatgagggaa ggtaggggag aatctagcca 4081 ttttataatg ccagaaatct atatatgtta tctgatgcca tttttctgaa gtagcctcac 4141 atgtggtccc cctgcagttc agcagttaac agatgacttt tttagtgtaa taaaatgttt 4201 atcatctacg aaaaaaaaaa aaaaaa //