LOCUS       BC025989                4226 bp    mRNA    linear   HUM 17-JUL-2006
DEFINITION  Homo sapiens leucyl-tRNA synthetase 2, mitochondrial, mRNA (cDNA
            clone MGC:26121 IMAGE:4822546), complete cds.
ACCESSION   BC025989
VERSION     BC025989.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4226)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 4226)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 25, 2003 this sequence version replaced BC025989.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
            cDNA Library Preparation: Michael J. Brownstein (NHGRI) &  Shiraki
            Toshiyuki and Piero Carninci (RIKEN)
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 33 Row: d Column: 7
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 41352689.
FEATURES             Location/Qualifiers
     source          1..4226
                     /db_xref="H-InvDB:HIT000040054"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:26121 IMAGE:4822546"
                     /tissue_type="Testis"
                     /clone_lib="NIH_MGC_97"
                     /lab_host="DH10B"
                     /note="Vector: pBluescriptR"
     gene            1..4226
                     /gene="LARS2"
                     /gene_synonym="KIAA0028"
                     /gene_synonym="LEURS"
                     /gene_synonym="MGC26121"
                     /db_xref="GeneID:23395"
                     /db_xref="HGNC:HGNC:17095"
                     /db_xref="MIM:604544"
     CDS             193..2904
                     /gene="LARS2"
                     /gene_synonym="KIAA0028"
                     /gene_synonym="LEURS"
                     /gene_synonym="MGC26121"
                     /codon_start=1
                     /product="leucyl-tRNA synthetase 2, mitochondrial"
                     /protein_id="AAH25989.1"
                     /db_xref="GeneID:23395"
                     /db_xref="HGNC:HGNC:17095"
                     /db_xref="MIM:604544"
                     /translation="MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSAT
                     GKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHV
                     RVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQ
                     LDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANE
                     QVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDC
                     VGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMA
                     LVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGL
                     AYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLIS
                     RQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPR
                     CKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVM
                     HLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVP
                     VHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKT
                     DALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVT
                     THFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSE
                     IWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVP
                     QQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD"
BASE COUNT         1082 a         1048 c         1138 g          958 t
ORIGIN      
        1 gctgttttga caacatggcg gcgcccatgg tccgtggccc ggcagtgctc gcctaaaggt
       61 ggagaacgag gagtagagga gccacaggcc agagcctgtg agcagatcca gacctacaga
      121 taaaaaacat tatttaatct atctgggatt tactccggct tatgatttga gggccttctc
      181 accttctgaa gaatggcttc tgtttggcag agattgggtt tttatgcctc tcttctgaaa
      241 agacagctaa atggtgggcc agatgtcatc aagtgggaaa ggagagtaat tcccggatgt
      301 accagaagca tctacagtgc cacgggaaag tggacaaaag agtatacatt gcagacaaga
      361 aaggatgttg agaaatggtg gcatcaacga ataaaagaac aggcctccaa aatttcagaa
      421 gctgataaat cgaagccaaa attttacgtg ctttccatgt tcccttatcc ttctggtaag
      481 ctgcacatgg gccatgtgcg tgtctacacc atcagcgaca ccatagcacg gttccagaag
      541 atgagaggga tgcaggtcat caaccccatg ggatgggatg cttttggatt gcctgctgaa
      601 aatgccgcag tcgagaggaa tctacatcca caaagttgga cacaaagtaa tattaaacac
      661 atgaggaaac agcttgatcg tctgggcctg tgtttcagct gggataggga aataactacg
      721 tgtttgccag attactacaa gtggactcag tatctcttta ttaaactgta tgaggctggg
      781 ctggcctatc aaaaggaggc cctggttaac tgggacccag tggatcaaac agtgcttgcc
      841 aatgagcagg tggatgaaca tggctgttca tggcgttctg gagcaaaggt ggaacagaag
      901 tacctcagac aatggtttat taagacaacc gcttatgcaa aggccatgca ggacgcgttg
      961 gcagaccttc cagaatggta tggaataaaa ggcatgcaag cccactggat tggggactgt
     1021 gtgggctgcc acctggactt cacattaaag gttcatgggc aagccacggg cgaaaagctg
     1081 actgcctata cggccacccc tgaagccatt tatggcacct cccacgtggc catctcgccc
     1141 agccacagac tcctacatgg gcacagctct ctgaaggaag ccttgaggat ggcccttgtc
     1201 cctggcaaag attgcctcac gcctgtaatg gctgtgaaca tgctcaccca gcaggaggtc
     1261 cctgtcgtta ttttggccaa agctgacttg gaaggctctc tggattcaaa aataggaatt
     1321 cccagtacta gctcagagga caccatctta gcccaaaccc tgggcctggc ctactctgaa
     1381 gtcattgaaa ctttgccaga tggcacagag agactgagca gctctgctga gttcacaggt
     1441 atgacccggc aggatgcttt tctagccctg actcagaaag cccgggggaa gagagtgggt
     1501 ggagacgtga caagtgataa actgaaagac tggctgattt cacggcagcg gtactggggc
     1561 acaccaatcc ccattgtcca ctgcccagtc tgtggcccca cacctgtgcc cctggaggac
     1621 ttgcctgtga ccctgcccaa catcgcatct ttcactggca agggaggccc cccactggcc
     1681 atggcttcag agtgggtgaa ctgctcctgc ccaaggtgca agggagcagc caagagagag
     1741 acagacacga tggatacctt tgttgattct gcttggtact acttcagata cactgaccct
     1801 cataatccac acagcccttt taacacagca gtggccgatt actggatgcc tgtggatttg
     1861 tacattggag ggaaagaaca tgccgtcatg cacttgttct atgcaagatt ctttagtcat
     1921 ttttgccatg atcaaaaaat ggttaaacat agggagcctt ttcataagct gctggcccaa
     1981 ggccttatca aggggcagac attccgccta ccatctggac agtatctaca gagagaggaa
     2041 gtggatctca caggttccgt tcctgttcat gcaaaaacga aagagaagtt agaggtgacg
     2101 tgggagaaga tgagtaagtc caaacacaac ggggtggacc cagaggaagt tgtggagcag
     2161 tatgggatcg acacgattcg gctctacatc ctttttgctg cccctcctga gaaggatatc
     2221 ttgtgggatg tgaaaactga tgctctccct ggggtgctga gatggcaaca acgactgtgg
     2281 accttgacaa ctcggtttat tgaggccagg gcttctggga agtctcccca gcctcagctg
     2341 ctgagtaaca aggagaaagc cgaggccagg aagctctggg agtacaagaa ctccgtcatc
     2401 tctcaggtga ccacccattt cacagaggac ttctcactga attctgcaat ttctcagctg
     2461 atgggactca gcaatgccct ctcgcaagcc tctcagagcg tcattctcca cagccccgag
     2521 tttgaggatg ctttgtgtgc cctgatggtg atggctgctc cactggcccc tcatgtaacc
     2581 tcagagatct gggcaggcct ggcgctggtg ccgaggaagc tctgtgccca ctacacttgg
     2641 gatgccagtg tgctgctcca ggcatggcct gctgtggacc cggagttcct gcagcagcct
     2701 gaggttgtcc agatggcagt tctgatcaac aataaagctt gtggcaaaat tcctgtgccc
     2761 caacaagttg cccgggacca ggacaaagtc cacgaatttg ttcttcaaag cgagctgggt
     2821 gtcaggcttt tgcaaggacg aagcatcaag aagtccttcc tttccccgag aactgccctc
     2881 atcaacttcc tggtgcaaga ttgacagcca gtaggctgca gctaccacga gggcctctga
     2941 ggaacctcct tccaggcctg ggatgagggg gcgatgtctg ctggcccagg ggaagggaaa
     3001 agacaaatgt cttgactgtt gacctcggtc ctgtggcaga ctgcagtcaa cagtgtgcct
     3061 ctgtagtgtg gcctggtgct ggggtgaagg tgagctgggc aaaggagaaa tatgagctac
     3121 tgaggagggg gttggacatc ctgcccctca ccccccaccc acactgcagg tagaggaggc
     3181 catctgatcc catgggaagc catcagagac actgctggtg ggagcaggaa ggagcagtgc
     3241 ccctcgagca gccaggaagc ctgcggatct gggaaatggc tctgccttag gcgcttctcg
     3301 ggaatttgag gccagcctga ggaactgcag gactcaggtg caatgtgcca gccacttgga
     3361 actgctaact gagcctccag atggtagtga atggtctctt tgccttcagg ctggatgagg
     3421 aagtcattta ggaaatgttc aaataaccaa tatgtggaaa tggacacagg gatcttctga
     3481 agttgctttg aatcaaaagg caggcagtgc tggttcctct gcctgtgtcc ccaccactcc
     3541 ccagctctgt catgcaggcc tgtcctcccc aaccccagct ggacgtgcct cccaggcctg
     3601 ctgtggttct gacacacagg atcccaggca aggcaccact tcctcacatg aatgaggagc
     3661 agcaagtcat aaccactccc ttgggtatac aatttgctgt gtagtgaagt ggaaccaggc
     3721 tcaggctgct ggtcccaacc tcagagcccc accgcagccc agtagggatg cagcacgccc
     3781 cagagggctc atgtgggccc cagatggcaa tgccaccatt gttgatgtga ctccagagcc
     3841 agttattagg aagagcaagc tcaccacaga ggagtggaac tgaggccccc cagatgttgc
     3901 ctccggtgtc caagccacag cggtctggct gttgggaaga tggccaggaa tggactcata
     3961 ccattggcac attaggctaa tcctggtttt atgtgaagtc agcaattaag tgttcccact
     4021 agaactgacc taagccactg attaatattt aatgagggaa ggtaggggag aatctagcca
     4081 ttttataatg ccagaaatct atatatgtta tctgatgcca tttttctgaa gtagcctcac
     4141 atgtggtccc cctgcagttc agcagttaac agatgacttt tttagtgtaa taaaatgttt
     4201 atcatctacg aaaaaaaaaa aaaaaa
//