LOCUS BC025699 2183 bp mRNA linear HUM 08-DEC-2006
DEFINITION Homo sapiens SMAD family member 2, mRNA (cDNA clone MGC:34440
IMAGE:5221801), complete cds.
ACCESSION BC025699
VERSION BC025699.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2183)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2183)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: k Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51173729.
FEATURES Location/Qualifiers
source 1..2183
/db_xref="H-InvDB:HIT000039967"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34440 IMAGE:5221801"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2183
/gene="SMAD2"
/gene_synonym="hMAD-2"
/gene_synonym="hSMAD2"
/gene_synonym="JV18"
/gene_synonym="JV18-1"
/gene_synonym="MADR2"
/gene_synonym="MGC22139"
/gene_synonym="MGC34440"
/db_xref="GeneID:4087"
/db_xref="HGNC:HGNC:6768"
/db_xref="MIM:601366"
CDS 107..1510
/gene="SMAD2"
/gene_synonym="hMAD-2"
/gene_synonym="hSMAD2"
/gene_synonym="JV18"
/gene_synonym="JV18-1"
/gene_synonym="MADR2"
/gene_synonym="MGC22139"
/gene_synonym="MGC34440"
/codon_start=1
/product="SMAD family member 2"
/protein_id="AAH25699.1"
/db_xref="GeneID:4087"
/db_xref="HGNC:HGNC:6768"
/db_xref="MIM:601366"
/translation="MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKA
VKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLY
SFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIP
ETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCS
IAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGR
GVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA
LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
KVLTQMGSPSVRCSSMS"
BASE COUNT 714 a 425 c 466 g 578 t
ORIGIN
1 ccgcggcggc ggagaagcag ctcgccagcc agcagcccgc cagccgccgg gaggttcgat
61 acaagaggct gttttcctag cgtggcttgc tgcctttggt aagaacatgt cgtccatctt
121 gccattcacg ccgccagttg tgaagagact gctgggatgg aagaagtcag ctggtgggtc
181 tggaggagca ggcggaggag agcagaatgg gcaggaagaa aagtggtgtg agaaagcagt
241 gaaaagtctg gtgaagaagc taaagaaaac aggacgatta gatgagcttg agaaagccat
301 caccactcaa aactgtaata ctaaatgtgt taccatacca agcacttgct ctgaaatttg
361 gggactgagt acaccaaata cgatagatca gtgggataca acaggccttt acagcttctc
421 tgaacaaacc aggtctcttg atggtcgtct ccaggtatcc catcgaaaag gattgccaca
481 tgttatatat tgccgattat ggcgctggcc tgatcttcac agtcatcatg aactcaaggc
541 aattgaaaac tgcgaatatg cttttaatct taaaaaggat gaagtatgtg taaaccctta
601 ccactatcag agagttgaga caccagtttt gcctccagta ttagtgcccc gacacaccga
661 gatcctaaca gaacttccgc ctctggatga ctatactcac tccattccag aaaacactaa
721 cttcccagca ggaattgagc cacagagtaa ttatattcca gaaacgccac ctcctggata
781 tatcagtgaa gatggagaaa caagtgacca acagttgaat caaagtatgg acacaggctc
841 tccagcagaa ctatctccta ctactctttc ccctgttaat catagcttgg atttacagcc
901 agttacttac tcagaacctg cattttggtg ttcgatagca tattatgaat taaatcagag
961 ggttggagaa accttccatg catcacagcc ctcactcact gtagatggct ttacagaccc
1021 atcaaattca gagaggttct gcttaggttt actctccaat gttaaccgaa atgccacggt
1081 agaaatgaca agaaggcata taggaagagg agtgcgctta tactacatag gtggggaagt
1141 ttttgctgag tgcctaagtg atagtgcaat ctttgtgcag agccccaatt gtaatcagag
1201 atatggctgg caccctgcaa cagtgtgtaa aattccacca ggctgtaatc tgaagatctt
1261 caacaaccag gaatttgctg ctcttctggc tcagtctgtt aatcagggtt ttgaagccgt
1321 ctatcagcta actagaatgt gcaccataag aatgagtttt gtgaaagggt ggggagcaga
1381 ataccgaagg cagacggtaa caagtactcc ttgctggatt gaacttcatc tgaatggacc
1441 tctacagtgg ttggacaaag tattaactca gatgggatcc ccttcagtgc gttgctcaag
1501 catgtcataa agcttcacca atcaagtccc atgaaaagac ttaatgtaac aactcttctg
1561 tcatagcatt gtgtgtggtc cctatggact gtttactatc caaaagttca agagagaaaa
1621 cagcacttga ggtctcatca attaaagcac cttgtggaat ctgtttccta tatttgaata
1681 ttagatggga aaattagtgt ctagaaatac tctcccatta aagaggaaga gaagatttta
1741 aagacttaat gatgtcttat tgggcataaa actgagtgtc ccaaaggttt attaataaca
1801 gtagtagtta tgtgtacagg taatgtatca tgatccagta tcacagtatt gtgctgttta
1861 tatacatttt tagtttgcat agatgaggtg tgtgtgtgcg ctgcttcttg atctaggcaa
1921 acctttataa agttgcagta cctaatctgt tattcccact tctctgttat ttttgtgtgt
1981 cttttttaat atataatata tatcaagatt ttcaaattat ttagaagcag attttcctgt
2041 agaaaaacta atttttctgc cttttaccaa aaataaactc ttgggggaag aaaagtggaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaaaaaaaa aaa
//