LOCUS BC025665 2805 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens polycystic kidney disease 2-like 1, mRNA (cDNA clone
MGC:34317 IMAGE:5200440), complete cds.
ACCESSION BC025665
VERSION BC025665.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2805)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2805)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: c Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33598943.
FEATURES Location/Qualifiers
source 1..2805
/db_xref="H-InvDB:HIT000039945"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34317 IMAGE:5200440"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2805
/gene="PKD2L1"
/gene_synonym="PCL"
/db_xref="GeneID:9033"
/db_xref="HGNC:HGNC:9011"
/db_xref="MIM:604532"
CDS 81..2498
/gene="PKD2L1"
/gene_synonym="PCL"
/codon_start=1
/product="polycystic kidney disease 2-like 1"
/protein_id="AAH25665.1"
/db_xref="GeneID:9033"
/db_xref="HGNC:HGNC:9011"
/db_xref="MIM:604532"
/translation="MNAVGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTG
PLQPQPKKPEDEPQETAYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLR
ELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDF
AQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFRE
DILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPG
SRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSW
QIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLV
VILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAW
IKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFST
FIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSE
VKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFTNT
LRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRS
IVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLER
KGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEVPYKREEEALEERRLSRGE
IPTLQRS"
BASE COUNT 723 a 719 c 742 g 621 t
ORIGIN
1 ggctgggctg tgcctctgct ccctcttcct ctagctgaga gtgggcacct ggggtaccgg
61 gcccccccac ctcattcccc atgaatgctg tgggaagtcc tgaggggcag gagctgcaaa
121 agctggggag tggagcctgg gacaaccccg cctacagtgg tcccccttcc ccacacggga
181 cgctgagagt ctgcaccatc tccagcacgg ggcctctcca gccccaaccc aagaagcctg
241 aagatgaacc ccaggagacg gcatacagga cccaggtgtc cagctgctgc ctccatatct
301 gtcaaggcat cagaggactt tggggaacaa ccctgactga gaacacagct gagaaccggg
361 aactttatat caagaccacc ctgagggagc tgttggtata tattgtgttc ctggtggaca
421 tctgtctact gacctatgga atgacaagct ccagtgctta ttactacacc aaagtgatgt
481 ctgagctctt cttacatact ccatcagaca ctggagtctc ctttcaggcc atcagcagca
541 tggcggactt ctgggatttt gcccagggcc cactactgga cagtttgtat tggaccaaat
601 ggtacaacaa ccagagcctg ggccatggct cccactcctt catctactat gagaacatgc
661 tgctgggggt tccgaggctg cggcagctaa aggtccgcaa tgactcctgt gtggtgcatg
721 aagacttccg ggaggacatt ctgagctgct atgatgtcta ctctccagac aaagaagaac
781 aactcccctt tgggcccttc aatggcacag cgtggacata ccactcgcag gatgagttgg
841 ggggcttctc ccactggggc aggctcacaa gctacagcgg aggtggctac tacctggacc
901 ttccaggatc ccgacagggt agtgcagagg ctctccgggc ccttcaggag gggctgtggc
961 tggacagggg cactcgagtg gtgttcatcg acttctcagt ctacaatgcc aatatcaatc
1021 ttttctgtgt cctgaggctg gtggtggagt ttccagctac aggaggtgcc atcccatcct
1081 ggcaaatccg cacagtcaag ctgatccgct atgtcagcaa ctgggacttc tttatcgttg
1141 gctgtgaggt catcttctgc gtcttcatct tctactatgt ggtggaagag atcctggagc
1201 tccacattca ccggcttcgc tacctcagca gcatctggaa catactggac ctggtggtca
1261 tcttgctctc cattgtggct gtgggcttcc acatattccg aaccctcgag gtgaatcggc
1321 tcatggggaa gctcctgcag cagccaaaca cgtatgcaga ctttgagttc ctcgccttct
1381 ggcagacaca gtacaacaac atgaatgctg tcaacctctt cttcgcctgg atcaagatat
1441 tcaagtacat cagcttcaac aaaaccatga cccagctctc ctccacgctg gcccgctgtg
1501 ccaaggacat cctgggcttc gccgtcatgt tcttcattgt tttcttcgcc tatgcccaac
1561 tcggctacct gcttttcggg acccaagtgg aaaactttag cactttcatc aagtgcattt
1621 tcactcagtt ccggataatc ctcggggact ttgactacaa tgctatcgac aatgccaacc
1681 gcatcctggg ccctgcctac tttgtcacct atgtcttctt cgtcttcttc gtgctcctga
1741 acatgttcct ggccatcatc aatgacacat attcagaggt caaggaggag ctggctggac
1801 agaaggatga gctgcaactt tctgacctcc tgaaacaggg ctacaacaag accctactaa
1861 gactgcgtct gaggaaggag agggtttcgg atgtgcagaa ggtcctgcag ggtggggagc
1921 aggagatcca gtttgaggat ttcaccaaca ccttaaggga actgggacac gcagagcatg
1981 aaatcactga gctcacggcc accttcacca agtttgacag agatgggaat cgtattctgg
2041 atgagaagga acaggaaaaa atgcgacagg acctggagga agagagggtg gccctcaaca
2101 ctgagattga gaaactaggc cgatctattg tgagcagccc acaaggcaaa tcgggtccag
2161 aggctgccag agcaggaggc tgggtttcag gagaagaatt ctacatgctc acaaggagag
2221 ttctgcagct ggagactgtc ctggaaggag tagtgtccca gattgatgct gtaggctcaa
2281 agctgaaaat gctggagagg aaggggtggc tggctccctc cccaggcgtg aaggaacaag
2341 ctatttggaa gcacccgcag ccagccccag ctgtgacccc agacccctgg ggagtccagg
2401 gtgggcagga gagtgaggtt ccctataaaa gagaagagga agccttagag gagaggagac
2461 tctcccgtgg tgagattcca acgttgcaga ggagttaagt gtgaggcact cccggagcaa
2521 agtctatgaa ggatcttctg caagaggctg cctcctggtc cactgaacct ggaaactgag
2581 tgggctttaa ccaggagata aaaatggagc ctgaagggaa tcaggcaagg aaatgaactc
2641 aggattcaga gatctttgaa ttaatatgtg gtgggttctg acattattct tccataagac
2701 catgtgggtt tccatggtgg ctatcaataa aactccttag gaaaaaaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//