LOCUS BC025295 2487 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sorbitol dehydrogenase, mRNA (cDNA clone MGC:39247
IMAGE:5428022), complete cds.
ACCESSION BC025295
VERSION BC025295.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2487)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2487)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: o Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147623.
FEATURES Location/Qualifiers
source 1..2487
/db_xref="H-InvDB:HIT000039887"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39247 IMAGE:5428022"
/tissue_type="Brain, astrocytoma, grade IV"
/clone_lib="NIH_MGC_98"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2487
/gene="SORD"
/gene_synonym="SORD1"
/db_xref="GeneID:6652"
/db_xref="HGNC:HGNC:11184"
/db_xref="MIM:182500"
CDS 79..1152
/gene="SORD"
/gene_synonym="SORD1"
/codon_start=1
/product="sorbitol dehydrogenase"
/protein_id="AAH25295.1"
/db_xref="GeneID:6652"
/db_xref="HGNC:HGNC:11184"
/db_xref="MIM:182500"
/translation="MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGI
CGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPREN
DEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSV
GIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGA
DLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLG
SEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEA
FETFKKGLGLKIMLKCDPSDQNP"
BASE COUNT 651 a 576 c 625 g 635 t
ORIGIN
1 ccctcggctg ggtagcgcca ccagagcgac caaacgtccc gcgccttcca ggccgcactc
61 cagagccaaa agagctccat ggcggcggcg gccaagccca acaacctttc cctggtggtg
121 cacggaccgg gggacttgcg cctggagaac tatcctatcc ctgaaccagg cccaaatgag
181 gtcttgctga ggatgcattc tgttggaatc tgtggctcag atgtccacta ctgggagtat
241 ggtcgaattg ggaattttat tgtgaaaaag cccatggtgc tgggacatga agcttcggga
301 acagtcgaaa aagtgggatc atcggtaaag cacctaaaac caggtgatcg tgttgccatc
361 gagcctggtg ctccccgaga aaatgatgaa ttctgcaaga tgggccgata caatctgtca
421 ccttccatct tcttctgtgc cacgcccccc gatgacggga acctctgccg gttctataag
481 cacaatgcag ccttttgtta caagcttcct gacaatgtca cctttgagga aggcgccctg
541 atcgagccac tttctgtggg gatccatgcc tgcaggagag gcggagttac cctgggacac
601 aaggtccttg tgtgtggagc tgggccaatc gggatggtca ctttgctcgt ggccaaagca
661 atgggagcag ctcaagtagt ggtgactgat ctgtctgcta cccgattgtc caaagccaag
721 gagattgggg ctgatttagt cctccagatc tccaaggaga gccctcagga aatcgccagg
781 aaagtagaag gtcagctggg gtgcaagccg gaagtcacca tcgagtgcac gggggcagag
841 gcctccatcc aggcgggcat ctacgccact cgctctggtg ggaccctcgt gcttgtgggg
901 ctgggctctg agatgaccac cgtaccccta ctgcatgcag ccatccggga ggtggatatc
961 aagggcgtgt ttcgatactg caacacgtgg ccagtggcga tttcgatgct tgcgtccaag
1021 tctgtgaatg taaaacccct cgtcacccat aggtttcctc tggagaaagc tctggaggcc
1081 tttgaaacat ttaaaaaggg attggggttg aaaatcatgc tcaagtgtga ccccagtgac
1141 cagaatccct gatgttaatg ggctctgccc tcatccccac agtcttggga tctcagggca
1201 caatggctgg acatgggtgg gctctgatgc agaactttct cttttgaatg ttaagaataa
1261 ctaatacaat tcattgtgaa cagaagtcct taagcagagg aattggtgtg ccttaaagat
1321 acaatctggg atagtttggg ggaacttgta gccagaatgc cctgttcatg ctgagcaaag
1381 ttcagcaagt agagcagagt ttggcaggca ggtgccagga actccccttc ttcctggagt
1441 gccttcattg aggaaggaaa tctggccctt gggtttcctg gttccactgc tactgaccca
1501 gaggggaatg agggctgagt tatgaaaaga taacttcatg aagacttaac tggcccagaa
1561 gctgattttc atgaaaatct gccactcagg gtctgggatg aaggcttgtc agcacttcca
1621 gtttagaacg caatgtttct agagacatat tggctgtttg ttttgatgat aaaaggagaa
1681 taagaaaagg catcactttc ctggatccag gataattttt aaaccaatca aatgaaaaaa
1741 acaaacaaac aaaaaaggaa atgtcatgtg aggttaaacc agtttgcatt cccctaatgt
1801 ggaaaaagta agaggactac tcagcactgt ttgaagattg cctcttctac agcttctgag
1861 aattgtgtta tttcacttgc caagtgaagg accccctccc caacatgccc cagcccaccc
1921 ctaagcatgg tcccttgtca ccaggcaacc aggaaactgc tacttgtgga cctcaccaga
1981 gaccaggagg gtttggttag ctcacaggac ttcccccacc ccagaagatt agcatcccat
2041 actagactca tactcaactc aactaggctc atactcaatt gatggttatt agacaattcc
2101 atttctttct ggttattata aacagaaaat ctttcctctt ctcattacca gtaaaggctc
2161 ttggtatctt tctgttggaa tgatttctat gaacttgtct tattttaatg gtgggttttt
2221 tttctggtaa gatttagacc taaatcgcat catgccaact tgtgactttg agactattca
2281 tcaagaatga ggatatagta gccatgacat agcttgagct atagccttta attccttact
2341 ttggctatgg gtggagggtg agtttgaaga ggttctgatt ttcttgtaac ctgggaaagc
2401 catgaccttg tgcccgattc tttcagattg ctttgggtaa taaatattgg tggtggtatc
2461 tgaaaaaaaa aaaaaaaaaa aaaaaaa
//