LOCUS BC025269 1264 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens trimethyllysine hydroxylase, epsilon, mRNA (cDNA clone
MGC:39168 IMAGE:3689631), complete cds.
ACCESSION BC025269
VERSION BC025269.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1264)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1264)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: b Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8922624.
FEATURES Location/Qualifiers
source 1..1264
/db_xref="H-InvDB:HIT000039874"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39168 IMAGE:3689631"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1264
/gene="TMLHE"
/gene_synonym="FLJ10727"
/gene_synonym="TMLH"
/db_xref="GeneID:55217"
CDS 88..1218
/gene="TMLHE"
/gene_synonym="FLJ10727"
/gene_synonym="TMLH"
/codon_start=1
/product="TMLHE protein"
/protein_id="AAH25269.1"
/db_xref="GeneID:55217"
/translation="MWYHRLSHLHSRLQDLLKGGVIYPALPQPNFKSLLPLAVHWHHT
ASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDL
CIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIYQQA
QVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYG
RMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFY
AAEQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRLF
KEKQNTVNRQWNSSLQCDIPERILTYRHFVSGTSIEHRGSLI"
misc_feature 283..996
/gene="TMLHE"
/gene_synonym="FLJ10727"
/gene_synonym="TMLH"
/note="Gamma-BBH; Region: Gamma-butyrobetaine hydroxylase.
Members of this family are gamma-Butyrobetaine hydroxylase
enzymes EC:1.14.11.1"
/db_xref="CDD:pfam03322"
BASE COUNT 387 a 285 c 276 g 316 t
ORIGIN
1 ggcgggtgaa aggctgcctc ccgagactct ccttgcttgg aattctgccc actctgcgga
61 gttagcagtc acgacctcca gcacaggatg tggtaccaca gattgtccca cctacacagc
121 aggcttcagg acttgctgaa gggaggagtc atatatccgg cccttccaca gcccaacttc
181 aaaagcttac ttcctttagc tgtccattgg caccatacag cctccaagtc tctgacttgt
241 gcttggcagc aacatgaaga tcattttgag ctgaaatatg ctaataccgt gatgcgcttt
301 gattacgtct ggcttcgaga ccactgccgc tcagcatcgt gctacaactc taagactcac
361 cagcgcagcc tggatactgc cagtgtggat ttatgtatca agccaaagac cattcgtctg
421 gatgagacca cactcttttt cacttggcca gatggtcatg tgactaaata tgatttgaat
481 tggctggtga aaaacagcta tgaagggcag aaacaaaaag tcatccagcc tagaatacta
541 tggaatgctg aaatctacca gcaagcccaa gttccatcgg tagattgcca gagcttctta
601 gaaaccaacg agggactgaa gaagtttctg caaaactttc tgctctatgg aattgcattc
661 gtagaaaatg tccctcccac tcaagagcac acagagaagt tggcagaaag gatcagctta
721 atcagagaaa ccatttatgg gaggatgtgg tatttcactt cagacttctc cagaggtgac
781 actgcgtaca ccaagctagc tctggatcgg cacactgaca ctacctattt tcaagagccc
841 tgtggcattc aagtgtttca ttgtcttaaa catgaaggaa ctggtggcag gacactgcta
901 gtagatggat tctatgcagc agaacaggta cttcaaaagg cacctgagga atttgaactc
961 ctcagtaaag tgccattgaa gcatgaatat attgaagatg ttggagaatg tcacaaccac
1021 atgattggga ttgggccagt cttaaatatc tacccatgga ataaagagct gtatttgatc
1081 agattattca aagaaaaaca aaacacggtc aacaggcagt ggaactcctc actccaatgt
1141 gatattcctg agagaatatt gacttatcgt cacttcgtct ctgggacaag tattgaacat
1201 aggggaagcc ttatataaaa ttgttcaata aacaaaagat gtctttaaaa aaaaaaaaaa
1261 aaaa
//