LOCUS BC025258 3515 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens T-box 3, mRNA (cDNA clone MGC:39139 IMAGE:5458526),
complete cds.
ACCESSION BC025258
VERSION BC025258.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3515)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3515)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: p Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47419906.
FEATURES Location/Qualifiers
source 1..3515
/db_xref="H-InvDB:HIT000039867"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39139 IMAGE:5458526"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_47"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3515
/gene="TBX3"
/gene_synonym="TBX3-ISO"
/gene_synonym="XHL"
/db_xref="GeneID:6926"
/db_xref="HGNC:HGNC:11602"
/db_xref="MIM:601621"
CDS 391..2622
/gene="TBX3"
/gene_synonym="TBX3-ISO"
/gene_synonym="XHL"
/codon_start=1
/product="T-box 3"
/protein_id="AAH25258.1"
/db_xref="GeneID:6926"
/db_xref="HGNC:HGNC:11602"
/db_xref="MIM:601621"
/translation="MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPAL
TLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDD
PKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADD
CRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHG
FTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPET
EFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENG
TSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDA
AKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLG
AEERRSPVREGTAPAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAPGLA
GQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAA
AQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVH
RHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPA
SVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRS
ASP"
BASE COUNT 770 a 1047 c 914 g 784 t
ORIGIN
1 gcagggctgg agtgtctatt tcgagctcag cggcagggct cgggcgcgag tcgagaccct
61 gctcgctcct ctcgcttctg aaaccgacgt tcaggagcgg ctttttaaaa acgcaaggca
121 caaggacggt cacccgcgcg actatgtttg ctgatttttc gccttgccct ctttaaaagc
181 ggcctcccat tctccaaaag acacttcccc tcctcccttt gaagtgcatt agttgtgatt
241 tctgcctcct tttctttttt ctttcttttt tgttttgctt tttcccccct tttgaattat
301 gtgctgctgt taaacaacaa caaaaaaaca acaaaacaca gcagctgcgg acttgtcccc
361 ggctggagcc cagcgccccg cctggagtgg atgagcctct ccatgagaga tccggtcatt
421 cctgggacaa gcatggccta ccatccgttc ctacctcacc gggcgccgga cttcgccatg
481 agcgcggtgc tgggtcacca gccgccgttc ttccccgcgc tgacgctgcc tcccaacggc
541 gcggcggcgc tctcgctgcc gggcgccctg gccaagccga tcatggatca attggtgggg
601 gcggccgaga ccggcatccc gttctcctcc ctggggcccc aggcgcatct gaggcctttg
661 aagaccatgg agcccgaaga agaggtggag gacgacccca aggtgcacct ggaggctaaa
721 gaactttggg atcagtttca caagcggggc accgagatgg tcattaccaa gtcgggaagg
781 cgaatgtttc ctccatttaa agtgagatgt tctgggctgg ataaaaaagc caaatacatt
841 ttattgatgg acattatagc tgctgatgac tgtcgttata aatttcacaa ttctcggtgg
901 atggtggctg gtaaggccga ccccgaaatg ccaaagagga tgtacattca cccggacagc
961 cccgctactg gggaacagtg gatgtccaaa gtcgtcactt tccacaaact gaaactcacc
1021 aacaacattt cagacaaaca tggatttact ttggccttcc caagtgatca cgctacgtgg
1081 caggggaatt atagttttgg tactcagact atattgaact ccatgcacaa ataccagccc
1141 cggttccaca ttgtaagagc caatgacatc ttgaaactcc cttatagtac atttcggaca
1201 tacttgttcc ccgaaactga attcatcgct gtgactgcat accagaatga taagataacc
1261 cagttaaaaa tagacaacaa cccttttgca aaaggtttcc gggacactgg aaatggccga
1321 agagaaaaaa gaaaacagct caccctgcag tccatgaggg tgtttgatga aagacacaaa
1381 aaggagaatg ggacctctga tgagtcctcc agtgaacaag cagctttcaa ctgcttcgcc
1441 caggcttctt ctccagccgc ctccactgta gggacatcga acctcaaaga tttatgtccc
1501 agcgagggtg agagcgacgc cgaggccgag agcaaagagg agcatggccc cgaggcctgc
1561 gacgcggcca agatctccac caccacgtcg gaggagccct gccgtgacaa gggcagcccc
1621 gcggtcaagg ctcacctttt cgctgctgag cggccccggg acagcgggcg gctggacaaa
1681 gcgtcgcccg actcacgcca tagccccgcc accatctcgt ccagcactcg cggcctgggc
1741 gcggaggagc gcaggagccc ggttcgcgag ggcacagcgc cggccaaggt ggaagaggcg
1801 cgcgcgctcc cgggcaagga ggccttcgcg ccgctcacgg tgcagacgga cgcggccgcc
1861 gcgcacctgg cccagggccc cctgcctggc ctcggcttcg ccccgggcct ggcgggccaa
1921 cagttcttca acgggcaccc gctcttcctg caccccagcc agtttgccat ggggggcgcc
1981 ttctccagca tggcggccgc tggcatgggt cccctcctgg ccacggtttc tggggcctcc
2041 accggtgtct cgggcctgga ttccacggcc atggcctctg ccgctgcggc gcagggactg
2101 tccggggcgt ccgcggccac cctgcccttc cacctccagc agcacgtcct ggcctctcag
2161 ggcctggcca tgtccccttt cggaagcctg ttcccttacc cctacacgta catggccgca
2221 gcggcggccg cctcctctgc ggcagcctcc agctcggtgc accgccaccc cttcctcaat
2281 ctgaacacca tgcgcccgcg gctgcgctac agcccctact ccatcccggt gccggtcccg
2341 gacggcagca gtctgctcac caccgccctg ccctccatgg cggcggccgc ggggcccctg
2401 gacggcaaag tcgccgccct ggccgccagc ccggcctcgg tggcagtgga ctcgggctct
2461 gaactcaaca gccgctcctc cacgctctcc tccagctcca tgtccttgtc gcccaaactc
2521 tgcgcggaga aagaggcggc caccagcgaa ctgcagagca tccagcggtt ggttagcggc
2581 ttggaagcca agccggacag gtcccgcagc gcgtccccgt agacccgtcc cagacacgtc
2641 ttttcattcc agtccagttc aggctgccgt gcactttgtc ggatataaaa taaaccacgg
2701 gcccgccatg gcgttagccc ttccttttgc agttgcgtct gggaaggggc cccggactcc
2761 ctcgagagaa tgtgctagag acagcccctg tcttcttggc gtggtttata tgtccgggat
2821 ctggatcaga ttctgggggc tcagaaacgt cggttgcatt gagctactgg gggtaggagt
2881 tccaacattt atgtccagag caacttccag caaggctggt ctgggtctct gcccaccagg
2941 cggggaggtg ttcaaagaca tctccctcag tgcggattta tatatatatt tttccttcac
3001 tgtgtcaagt ggaaacaaaa acaaaatctt tcaaaaaaaa aatccggaca agtgaacaca
3061 ttaacatgat tctgtttgtg cagattaaaa actttatagg gacttgcatt atcggttctc
3121 aataaattac tgagcagctt tgtttgggga gggaagtccc taccatcctt gtttagtcta
3181 tattaagaaa atctgtgtct ttttaatatt cttgtgatgt tttcagagcc gctgtaggtc
3241 tcttcttgca tgtccacagt aatgtatttg tggtttttat tttgaacgct tgcttttaga
3301 gagaaaacaa tatagccccc tacccttttc ccaatccttt gccctcaaat cagtgaccca
3361 agggaggggg ggatttaaag ggaaggagtg ggcaaaacac ataaaatgaa tttattatat
3421 ctaagctctg tagcaggatt catgtcgttc tttgacagtt ctttctcttt cctgtatatg
3481 caataacaag gttttaaaaa aaaaaaaaaa aaaaa
//