LOCUS BC024287 1421 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 4-hydroxyphenylpyruvate dioxygenase, mRNA (cDNA clone
MGC:39261 IMAGE:5087393), complete cds.
ACCESSION BC024287
VERSION BC024287.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1421)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1421)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CGAP (Stanford)
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: m Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38016938.
FEATURES Location/Qualifiers
source 1..1421
/db_xref="H-InvDB:HIT000039806"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39261 IMAGE:5087393"
/tissue_type="Liver, hepatocellular carcinoma"
/clone_lib="NIH_MGC_100"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..1421
/gene="HPD"
/db_xref="GeneID:3242"
/db_xref="HGNC:HGNC:5147"
/db_xref="MIM:609695"
CDS 23..1204
/gene="HPD"
/codon_start=1
/product="4-hydroxyphenylpyruvate dioxygenase"
/protein_id="AAH24287.1"
/db_xref="GeneID:3242"
/db_xref="HGNC:HGNC:5147"
/db_xref="MIM:609695"
/translation="MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEP
LAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVED
CDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGY
EAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVH
TEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIIT
AIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQ
IFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVPG
M"
BASE COUNT 364 a 412 c 387 g 258 t
ORIGIN
1 ggaggtttga ctaagatcaa tcatgacgac ttacagtgac aaaggggcaa agcctgagag
61 aggccgattc ctccacttcc actctgtgac cttctgggtt ggcaacgcca agcaggccgc
121 gtcattctac tgcagcaaga tgggctttga acctctagcc tacaggggcc tggagaccgg
181 ttcccgggag gtggtcagcc atgtaatcaa acaagggaag attgtgtttg tcctctcctc
241 agcgctcaac ccctggaaca aagagatggg cgatcacctg gtgaaacacg gtgacggagt
301 gaaggacatt gcgttcgagg tggaagattg tgactacatc gtgcagaaag cacgggaacg
361 gggcgccaaa atcatgcggg agccctgggt agagcaagac aagtttggga aggtgaagtt
421 tgctgtgctg cagacgtatg gggacaccac acacaccctg gtggagaaga tgaactacat
481 cggccaattc ttgcctggat atgaggcccc agcgttcatg gaccccctac ttcctaaact
541 gcccaaatgc agtctggaga tgatcgacca cattgtggga aaccagcctg atcaggagat
601 ggtgtccgcc tccgaatggt acctgaaaaa cctgcagttc caccgcttct ggtccgtgga
661 tgacacgcag gtgcacacgg aatatagctc tctgcgatcc attgtggtgg ccaactatga
721 agagtccatc aagatgccca tcaatgagcc agcgcctggc aagaagaagt cccagatcca
781 ggaatatgtg gactataacg ggggcgctgg ggtccagcac atcgctctca agaccgaaga
841 catcatcaca gcgattcgcc acttgagaga gagaggcctg gagttcttat ctgttccctc
901 cacgtactac aaacaactgc gggagaagct gaagacggcc aagatcaagg tgaaggagaa
961 cattgatgcc ctggaggagc tgaaaatcct ggtggactac gacgagaaag gctacctcct
1021 gcagatcttc accaaaccgg tgcaggaccg gcccacgctc ttcctggaag tcatccagcg
1081 ccacaaccac cagggttttg gagccggcaa cttcaactca ctgttcaagg ctttcgagga
1141 ggagcagaac ctgcggggta acctcaccaa catggagacc aatggggtgg tgcccggcat
1201 gtaagccccg cccaccccac ggaggccaca gccacacagc cacgccccct gattctggaa
1261 ctcgcccaac ttccctactg gctgctcccc ttgggtcccg cccaccagcg gactcggccc
1321 ccaaggctcc gcccacactg accacgcccc tcggcggggc cgccctctgc tccagccctc
1381 ccgattaaag cgtgccccgg tccaaaaaaa aaaaaaaaaa a
//