LOCUS BC024285 2312 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens growth factor receptor-bound protein 10, mRNA (cDNA
clone MGC:39227 IMAGE:4590330), complete cds.
ACCESSION BC024285
VERSION BC024285.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2312)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2312)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: e Column: 24.
FEATURES Location/Qualifiers
source 1..2312
/db_xref="H-InvDB:HIT000039805"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39227 IMAGE:4590330"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2312
/gene="GRB10"
/gene_synonym="GRB-IR"
/gene_synonym="IRBP"
/gene_synonym="KIAA0207"
/gene_synonym="MEG1"
/gene_synonym="RSS"
/db_xref="GeneID:2887"
/db_xref="HGNC:HGNC:4564"
/db_xref="MIM:601523"
CDS 310..1920
/gene="GRB10"
/gene_synonym="GRB-IR"
/gene_synonym="IRBP"
/gene_synonym="KIAA0207"
/gene_synonym="MEG1"
/gene_synonym="RSS"
/codon_start=1
/product="growth factor receptor-bound protein 10"
/protein_id="AAH24285.1"
/db_xref="GeneID:2887"
/db_xref="HGNC:HGNC:4564"
/db_xref="MIM:601523"
/translation="MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQ
VSPRQRVQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLP
PSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHL
GLERCLEDHELVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGS
QTQLLQNFLNSSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQ
LLADLEDSNIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMT
AFRLLKYGMLLYQNYRIPQQRKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAE
AQSAALEEGHAWRKRSTRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIK
QQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSD
LIQLVDFYQLNKGVLPCKLKHHCIRVAL"
BASE COUNT 614 a 611 c 623 g 464 t
ORIGIN
1 gagccgcgcg cggcagcttt ggcgctgacc acaatgctga gcaggaagca gcagctgcag
61 gcccagtgac tggtagctca gtgaccagca gcccagtgac cggcagccag gtcctcacct
121 gggtcctctc agtgaagcca gggtggccgc cccagcagac agtgctacag agccaactcc
181 tgacaggaca aggtggagca gacacctcgc agtcaacaag acccggcagg accaggactc
241 cccgcacagt ctgaccgact tgcgaatcac caggaggatg atgtggacct ggaagccctg
301 gtgaacgata tgaatgcatc cctggagagc ctgtactcgg cctgcagcat gcagtcagac
361 acggtgcccc tcctgcagaa tggccagcat gcccgcagcc agcctcgggc ttcaggccct
421 cctcggtcca tccagccaca ggtgtcccca aggcagaggg tgcagcgctc ccagcctgtg
481 cacatcctcg ctgtcaggcg ccttcaggag gaagaccagc agtttagaac ctcatctctg
541 ccggccatcc ccaatccttt tcctgaactc tgtggccctg ggagcccccc tgtgctcacg
601 ccgggttctt tacctccgag ccaggccgcc gcaaagcagg atgttaaagt ctttagtgaa
661 gatgggacaa gcaaagtggt ggagattcta gcagacatga cagccagaga cctgtgccaa
721 ttgctggttt acaaaagtca ctgtgtggat gacaacagct ggacactagt ggagcaccac
781 ccgcacctag gattagagag gtgcttggaa gaccatgagc tggtggtcca ggtggagagt
841 accatggcca gtgagagtaa atttctattc aggaagaatt acgcaaaata cgagttcttt
901 aaaaatccca tgaatttctt cccagaacag atggttactt ggtgccagca gtcaaatggc
961 agtcaaaccc agcttttgca gaattttctg aactccagta gttgtcctga aattcaaggg
1021 tttttgcatg tgaaagagct gggaaagaaa tcatggaaaa agctgtatgt gtgtttgcgg
1081 agatctggcc tttattgctc caccaaggga acttcaaagg aacccagaca cctgcagctg
1141 ctggccgacc tggaggacag caacatcttc tccctgatcg ctggcaggaa gcagtacaac
1201 gcccctacag accacgggct ctgcataaag ccaaacaaag tcaggaatga aactaaagag
1261 ctgaggttgc tctgtgcaga ggacgagcaa accaggacgt gctggatgac agcgttcaga
1321 ctcctcaagt atggaatgct cctttaccag aattaccgaa tccctcagca gaggaaggcc
1381 ttgctgtccc cgttctcgac gccagtgcgc agtgtctccg agaactccct cgtggcaatg
1441 gatttttctg ggcaaacagg acgcgtgata gagaatccgg cggaggccca gagcgcagcc
1501 ctggaggagg gccacgcctg gaggaagcga agcacacgga tgaacatcct aggtagccaa
1561 agtcccctcc acccttctac cctaagtaca gtgattcaca ggacacagca ctggtttcac
1621 gggaggatct ccagggagga atcccacagg atcattaaac agcaagggct cgtggatggg
1681 ctttttctcc tccgtgacag ccagagtaat ccaaaggcat ttgtactcac actgtgtcat
1741 caccagaaaa ttaaaaattt ccagatctta ccttgcgagg acgacgggca gacgttcttc
1801 agcctagatg acgggaacac caaattctct gacctgatcc agctggttga cttttaccag
1861 ctgaacaaag gagtcctgcc ttgcaaactc aagcaccact gcatccgagt ggccttatga
1921 ccgcagatgt cctctcggct gaagactgga ggaagtgaac actggagtga agaagcggtc
1981 tgtgcgttgg tgaagaacac acatcgattc tgcacctggg gacccagagc gagatgggtt
2041 tgttcggtgc cagccgacca agattgacta gtttgttgga cttaaacgac gatttgctgc
2101 tgtgaaccca gcagggtcgc ctccctctgc gtcggccaaa ttggggaggg catggaagat
2161 ccagcggaaa gttgaaaata aactggaatg atcatcttgg cttgggccgc ttaggaacaa
2221 gaaccggaga gaagtgattg gaaatgaact cttgccctgg aataatcttg acaattaaaa
2281 ctgatatgtt taaaaaaaaa aaaaaaaaaa aa
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